Colchicine

ATP binding cassette subfamily B member 1 ; Homo sapiens







108 Article(s)
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51 10764626 Low-level doxorubicin resistance in benzo[a]pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution. 2000 Apr 15 1
52 10841824 Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism. 2000 Jun 7 1
53 10861470 Differential expression of sphingolipids in MRP1 overexpressing HT29 cells. 2000 Jul 15 3
54 10974159 Monitoring interactions at ATP-dependent drug efflux pumps. 2000 Nov 1
55 11321524 P-glycoprotein, glutathione and glutathione S-transferase increase in a colon carcinoma cell line by colchicine. 2000 Dec 4
56 9891078 Studies of human MDR1-MDR2 chimeras demonstrate the functional exchangeability of a major transmembrane segment of the multidrug transporter and phosphatidylcholine flippase. 1999 Feb 4
57 10079321 Visualization of multidrug resistance in vivo. 1999 Mar 1
58 9551613 Efficient transduction of human hematopoietic cells with the human multidrug resistance gene 1 via SV40 pseudovirions. 1998 Mar 20 1
59 9619779 P-glycoprotein is more efficient at limiting uptake than inducing efflux of colchicine and vinblastine in HL-60 cells. 1998 May 3
60 9667638 Influence of exogenous RAR alpha gene on MDR1 expression and P-glycoprotein function in human and rodent cell lines. 1998 Jun 2
61 9677321 Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation. 1998 Aug 1 1
62 9776981 Construction and characterization of single-transcript tricistronic retroviral vectors using two internal ribosome entry sites. 1998 Jan 1
63 9848464 Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? 1998 Nov 2
64 10021886 [The causes of treatment ineffectiveness in acute myelogenous leukemia--the role of blast resistance to cytotoxic drugs]. 1998 1
65 10367565 Induction of P-glycoprotein functional activity and multidrug resistance by a soluble factor(s) produced by some mammalian cells. 1998 2
66 9220975 Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human MDR1/P-glycoprotein. 1997 Jul 22 1
67 9256153 Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter. 1997 Jun 15 1
68 9287159 Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts. 1997 Sep 16 1
69 9405384 Identification of residues in the drug-binding site of human P-glycoprotein using a thiol-reactive substrate. 1997 Dec 19 1
70 8567633 Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein. 1996 Jan 26 1
71 8599208 Bicistronic and two-gene retroviral vectors for using MDR1 as a selectable marker and a therapeutic gene. 1996 Mar 1 2
72 8676093 The multidrug resistance phenotype confers immunological resistance. 1996 Jun 1 1
73 8784446 Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)]metal(III) cations. 1996 Aug 30 3
74 8934230 Complete restoration of glucocerebrosidase deficiency in Gaucher fibroblasts using a bicistronic MDR retrovirus and a new selection strategy. 1996 Nov 10 2
75 8938483 Markedly altered colchicine kinetics in a fatal intoxication: examination of contributing factors. 1996 Nov 1
76 8973548 Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport. 1996 Dec 1 2
77 8980113 Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins. 1996 Dec 9 2
78 7670142 Development of drug resistance is reduced with idarubicin relative to other anthracyclines. 1995 Jun 1
79 7822320 Membrane topology of a cysteine-less mutant of human P-glycoprotein. 1995 Jan 13 1
80 7896810 Mutation of glycine 185 to valine alters the ATPase function of the human P-glycoprotein expressed in Sf9 cells. 1995 Mar 24 2
81 8525161 [Colchicine: recent data on pharmacokinetics and clinical pharmacology]. 1995 3
82 8527864 Influence of exogenous ras and p53 on P-glycoprotein function in immortalized rodent fibroblasts. 1995 3
83 7865904 P-glycoprotein mediates profound resistance to bisantrene. 1994 2
84 7872686 Effects of vinblastine, colchicine, and verapamil on rhodamine 123 accumulation in human P-glycoprotein-positive leukemia cells. 1994 Nov-Dec 1
85 7904476 N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells. 1994 Jan 11 1
86 7909435 Drugs transported by P-glycoprotein inhibit a 40 pS outwardly rectifying chloride channel. 1994 Apr 15 1
87 7947814 Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein. 1994 Nov 29 1
88 7901214 Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein. 1993 Nov 15 1
89 7903407 Effect of multidrug-resistant P-glycoprotein gene expression on chloroaluminum tetrasulfonate phthalocyanine concentration. 1993 1
90 7912874 [Expression of human multidrug resistance gene (mdr1) cDNA in murine ES cells and in chimeric mice]. 1993 Dec 1
91 1356264 Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis. 1992 Sep 15 1
92 1611154 Double minute chromosomes carrying the human multidrug resistance 1 and 2 genes are generated from the dimerization of submicroscopic circular DNAs in colchicine-selected KB carcinoma cells. 1992 May 2
93 1653364 Effect of recombinant fibroblast interferon and recombinant immune interferon on growth and the antigenic phenotype of multidrug-resistant human glioblastoma multiforme cells. 1991 Sep 18 2
94 1676033 Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MRD1 gene expression. 1991 Mar 2
95 1967551 Binding of an optically pure photoaffinity analogue of verapamil, LU-49888, to P-glycoprotein from multidrug-resistant human leukemic cell lines. 1990 Feb 15 1
96 1968359 Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA. 1990 Mar 15 2
97 1976255 Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein. 1990 Sep 6
98 2568832 P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance. 1989 Jul 14 1
99 2569930 Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells. 1989 Sep 15 1
100 2570611 Biosynthesis, processing and half-life of P-glycoprotein in a human multidrug-resistant KB cell. 1989 Sep 15 1