Daunorubicin

ATP binding cassette subfamily B member 1 ; Homo sapiens







226 Article(s)
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151 9570100 Enzymatic synthesis of [4-methoxy-11C]daunorubicin for functional imaging of P-glycoprotein with PET. 1998 Jul 1
152 9592977 P-glycoprotein (PGP), and not lung resistance-related protein (LRP), is a negative prognostic factor in secondary leukemias. 1998 Apr 1
153 9744556 Kinetic analysis in living cells of the inhibition of the P-glycoprotein-mediated efflux of anthracyclines by vinca alkaloids. 1998 Jul 3 1
154 9753037 Decreased activity of the multidrug resistance P-glycoprotein in acquired aplastic anaemia: possible pathophysiologic implications. 1998 Sep 2
155 8960067 Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. 1997 Jan 10 1
156 9001418 A novel energy dependent mechanism reducing daunorubicin accumulation in acute myeloid leukemia. 1997 Jan 1
157 9029025 P-glycoprotein (PGP) and lung resistance-related protein (LRP) expression and function in leukaemic blast cells. 1997 Feb 1
158 9063374 Idarubicin monotherapy in multiply pretreated leukemia patients: response in relation to P-glycoprotein expression. 1997 Feb 1
159 9163728 Isolation and characterization of daunorubicin-resistant AML-2 sublines. 1997 Apr 30 1
160 9180292 The combined effects of IL-3 and PSC 833 on daunorubicin- and mitoxantrone cytotoxicity in two growth factor-dependent leukemic cell lines. 1997 May 2
161 9252419 Localization of the iodomycin binding site in hamster P-glycoprotein. 1997 Aug 15 1
162 9353133 P-glycoprotein-independent decrease in drug accumulation by phorbol ester treatment of tumor cells. 1997 Oct 1 6
163 9376262 Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain. 1997 3
164 9639738 [The relationship between multi-drug resistance gene expression and drug resistance of ovarian carcinoma]. 1997 Aug 1
165 9815696 A patient with adrenocortical carcinoma: characterization of its biological activity and drug resistance profile. 1997 Mar 1
166 8558937 Expression of multidrug resistance-associated protein (MRP) mRNA in blast cells from acute myeloid leukemia (AML) patients. 1996 Jan 1
167 8616077 Levels of mdr1 and mrp mRNA in leukaemic cell populations from patients with acute myelocytic leukaemia are heterogenous and inversely correlated to cellular daunorubicin accumulation. 1996 Mar 1
168 8643093 Relation among the resistance factor, kinetics of uptake, and kinetics of the P-glycoprotein-mediated efflux of doxorubicin, daunorubicin, 8-(S)-fluoroidarubicin, and idarubicin in multidrug-resistant K562 cells. 1996 Mar 2
169 8676093 The multidrug resistance phenotype confers immunological resistance. 1996 Jun 1 1
170 8688320 Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas. 1996 Jul 2
171 8774266 Modulation of multidrug resistance gene (mdr-1) with antisense oligodeoxynucleotides. 1996 Jul 1
172 8862011 Anthracycline drugs and MDR expression in human leukemia. 1996 1
173 8913319 Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells. 1996 Aug 2
174 9081366 Modulation of P-glycoprotein mediated drug accumulation in multidrug resistant CCRF VCR-1000 cells by chemosensitisers. 1996 May 1
175 9816184 Sensitive and rapid bioassay for analysis of P-glycoprotein-inhibiting activity of chemosensitizers in patient serum. 1996 Feb 2
176 9816222 Cyclosporin A and PSC 833 prevent up-regulation of MDR1 expression by anthracyclines in a human multidrug-resistant cell line. 1996 Apr 1
177 7475279 Discordant P-glycoprotein antigen expression and transport function in acute myeloid leukemia. 1995 Nov 2
178 7499263 Volume-sensitive chloride channel activity does not depend on endogenous P-glycoprotein. 1995 Nov 17 1
179 7575653 Behavior of N-acylated daunorubicins in MDR1 gene transfected and parental cells. 1995 Sep 7 2
180 7587719 Influence of S9788, a new modulator of multidrug resistance, on the cellular accumulation and subcellular distribution of daunorubicin in P-glycoprotein-expressing MCF7 human breast adenocarcinoma cells. 1995 Aug 1 1
181 7656812 [Reduced intracellular drug accumulation related to overexpression of P-glycoprotein cannot explain the complete drug resistance in MDR cell variant K562/Dox]. 1995 Mar 1
182 7670142 Development of drug resistance is reduced with idarubicin relative to other anthracyclines. 1995 Jun 1
183 7734315 Rapid up-regulation of mdr1 expression by anthracyclines in a classical multidrug-resistant cell line. 1995 May 6
184 7769842 Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cell lines. 1995 May 2
185 7794760 Circumvention of P-glycoprotein-mediated drug resistance in human leukaemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833. 1995 Jun 2
186 8586906 Modulation of daunorubicin intracellular accumulation in P-glycoprotein expressing MCF-7 human breast adenocarcinoma cells by thermosensitive-liposome encapsulation and hyperthermia. 1995 Nov-Dec 2
187 8835287 Differential interactions of cytochalasins with P-glycoprotein. 1995 1
188 7727866 [Methods for diagnosing MDR: immunohistochemistry versus molecular biology]. 1994 Dec 1
189 7909435 Drugs transported by P-glycoprotein inhibit a 40 pS outwardly rectifying chloride channel. 1994 Apr 15 1
190 7909520 The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate. 1994 Apr 1 4
191 7912204 Cooperative P-glycoprotein mediated daunorubicin transport into DNA-loaded plasma membrane vesicles. 1994 Jun 13 1
192 7912556 Comparative evaluation of S9788, verapamil, and cyclosporine A in K562 human leukemia cell lines and in P-glycoprotein-expressing samples from patients with hematologic malignancies. 1994 Jul 1 1
193 7913494 Enhanced transepithelial flux of cimetidine by Madin-Darby canine kidney cells overexpressing human P-glycoprotein. 1994 Jul 1
194 7914421 Reversion of multidrug resistance in the P-glycoprotein-positive human pancreatic cell line (EPP85-181RDB) by introduction of a hammerhead ribozyme. 1994 Aug 2
195 7914424 Daunorubicin pharmacokinetics and the correlation with P-glycoprotein and response in patients with acute leukaemia. 1994 Aug 3
196 7914749 Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes--first experience with their reversal. 1994 1
197 7927929 Daunorubicin efflux against a concentration gradient in non-P-glycoprotein multidrug-resistant lung-cancer cells. 1994 Oct 15 1
198 7977168 A phase II trial of DaunoXome, liposome-encapsulated daunorubicin, in patients with metastatic adenocarcinoma of the colon. 1994 Dec 1
199 7986198 Comparison of mechanisms responsible for resistance to idarubicin and daunorubicin in multidrug resistant LoVo cell lines. 1994 Nov 16 4
200 7905300 Atypical multi-drug resistance (MDR): low sensitivity of a P-glycoprotein-expressing human T lymphoblastoid MDR cell line to classical P-glycoprotein-directed resistance-modulating agents. 1993 Dec 4