Tacrolimus

ATP binding cassette subfamily B member 1 ; Homo sapiens







227 Article(s)
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1 34993577 Tacrolimus induces remission in refractory and relapsing lupus nephritis by decreasing P-glycoprotein expression and function on peripheral blood lymphocytes. 2022 Jan 7 4
2 35132839 Flat Pattern Peaks of Tacrolimus Absorption and Associated Pharmacogenomic Variants in Kidney Transplantation Recipients. 2022 Feb 7 1
3 35487881 Effects of ABCB1 DNA methylation in donors on tacrolimus blood concentrations in recipients following liver transplantation. 2022 Apr 29 8
4 35536394 The pharmacokinetics of tacrolimus in peripheral blood mononuclear cells and limited sampling strategy for estimation of exposure in renal transplant recipients. 2022 May 10 2
5 32803289 Diltiazem on tacrolimus exposure and dose sparing in Chinese pediatric primary nephrotic syndrome: impact of CYP3A4, CYP3A5, ABCB1, and SLCO1B3 polymorphisms. 2021 Jan 2
6 33962777 Impact of Clotrimazole Fungal Prophylaxis on Tacrolimus Exposure in Kidney Transplant Recipients: A Retrospective Study. 2021 Jun 1
7 34104149 Influence of ABCB1 gene polymorphism on concentration to dose ratio and adverse effects of tacrolimus in Pakistani liver transplant recipients. 2021 May-Jun 6
8 34269803 Genetic variants associated with cytomegalovirus infection after allogeneic hematopoietic cell transplantation. 2021 Oct 28 1
9 34285488 Clinical Evaluation of the Efficacy and Safety of Co-Administration of Wuzhi Capsule and Tacrolimus in Adult Chinese Patients with Myasthenia Gravis. 2021 2
10 34483924 Case Report: Low Hematocrit Leading to Tacrolimus Toxicity. 2021 1
11 34620272 Tacrolimus and herbs interactions: a review. 2021 Oct 1 1
12 34735949 Computational validation of ABCB1 gene polymorphism and its effect on tacrolimus dose concentration/levels in renal transplant individuals of South India. 2021 Dec 1
13 31441337 Clinical Controversy in Transplantation: Tacrolimus Versus Cyclosporine in Statin Drug Interactions. 2020 Feb 1
14 31756280 Clinically significant drug-drug interaction between tacrolimus and fluconazole in stable renal transplant recipient and literature review. 2020 Apr 1
15 31922058 Melding Pharmacogenomic Effect of MDR1 and CYP3A5 Gene Polymorphism on Tacrolimus Dosing in Renal Transplant Recipients in Northern India. 2020 Jan 3
16 32013193 Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients. 2020 Jan 29 3
17 32453653 Effects of CYP3A5, ABCB1 and POR*28 polymorphisms on pharmacokinetics of tacrolimus in the early period after renal transplantation. 2020 Dec 1
18 32657689 CYP3A5 polymorphisms and their effects on tacrolimus exposure in an ethnically diverse South African renal transplant population. 2020 Jan 29 1
19 32712713 Flucloxacillin decreases tacrolimus blood trough levels: a single-center retrospective cohort study. 2020 Dec 1
20 32849848 Beyond Single Nucleotide Polymorphisms: CYP3A5367 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White Renal Transplant Recipients. 2020 9
21 32888708 Effect of ABCB1 3435C>T Genetic Polymorphism on Pharmacokinetic Variables of Tacrolimus in Adult Renal Transplant Recipients: A Systematic Review and Meta-analysis. 2020 Oct 9
22 30471066 Conversion from Twice-Daily Prograf® to Once-Daily Advagraf® in Multi-ethnic Asian Adult Renal Transplant Recipients With or Without Concomitant Use of Diltiazem: Impact of CYP3A5 and MDR1 Genetic Polymorphisms on Tacrolimus Exposure. 2019 Aug 2
23 30489455 Effect of tacrolimus dispositional genetics on acute rejection in the first 2 weeks and estimated glomerular filtration rate in the first 3 months following kidney transplantation. 2019 Jan 6
24 30597277 Effect of CYP3A4, CYP3A5, and ABCB1 Polymorphisms on Intravenous Tacrolimus Exposure and Adverse Events in Adult Allogeneic Stem Cell Transplant Patients. 2019 Apr 3
25 30713247 Optimization of Individual Pharmacotherapy Based on Multiple Evaluations of Patient Data. 2019 3
26 30979494 Gene Polymorphism of Tacrolimus-Metabolizing Enzymes Associated With Impaired Absorption of Tacrolimus Following Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report. 2019 Apr 4
27 31003147 Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases. 2019 Jun 3
28 31423060 Influence of CYP3A5 and ABCB1 Polymorphism on Tacrolimus Drug Dosing in South Indian Renal Allograft Recipients. 2019 Jul-Aug 5
29 31454358 Retraction: Association of MDR1 Gene SNPs and Haplotypes with the Tacrolimus Dose Requirements in Han Chinese Liver Transplant Recipients. 2019 1
30 31588879 Impact of CYP3A4/5 and ABCB1 polymorphisms on tacrolimus exposure and response in pediatric primary nephrotic syndrome. 2019 Oct 1
31 31710427 Effect of CYP3A5 and ABCB1 Gene Polymorphisms on Tacrolimus Blood Concentration in Renal Transplant Recipients. 2019 Nov 1 2
32 28094348 Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant. 2018 Jan 1
33 29055041 The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study. 2018 Jan 4
34 29603629 CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. 2018 Sep 1
35 29615122 Effect of CYP3 A4, CYP3 A5 and ABCB1 gene polymorphisms on the clinical efficacy of tacrolimus in the treatment of nephrotic syndrome. 2018 Apr 3 1
36 29621269 Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation. 2018 2
37 29689130 A donor and recipient candidate gene association study of allograft loss in renal transplant recipients receiving a tacrolimus-based regimen. 2018 Dec 1
38 29775201 Tacrolimus Population Pharmacokinetics and Multiple CYP3A5 Genotypes in Black and White Renal Transplant Recipients. 2018 Sep 1
39 29920787 Genotypes associated with tacrolimus pharmacokinetics impact clinical outcomes in lung transplant recipients. 2018 Aug 2
40 29991328 CYP3A5 and ABCB1 polymorphisms in living donors do not impact clinical outcome after kidney transplantation. 2018 Jul 1 1
41 30166405 Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers. 2018 Nov 1
42 30251601 Influence of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics/Pharmacodynamics of Tacrolimus in Pediatric Patients. 2018 3
43 27378609 Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype. 2017 Dec 1
44 28135009 ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis. 2017 Sep 4
45 28214069 [Pharmacokinetic drug interaction between miconazole mucoadhesive tablet and tacrolimus: About 3 case-reports in transplant patients]. 2017 Sep 1
46 28655393 The role of single nucleotide polymorphisms of CYP3A and ABCB1 on tacrolimus predose concentration in kidney transplant recipients. 2017 Supplement 1 1
47 28736028 Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms. 2017 Jul - Aug 3
48 29279557 Effectiveness of Measuring Genetic Polymorphisms in Metabolizing Enzymes of Tacrolimus within One Medical Facility. 2017 1
49 26705892 The importance of MDR1 gene polymorphisms for tacrolimus dosage. 2016 Feb 15 3
50 26784512 Donor ABCB1 3435 C>T genetic polymorphisms influence early renal function in kidney transplant recipients treated with tacrolimus. 2016 Feb 2