Valproic Acid

ATP binding cassette subfamily B member 1 ; Homo sapiens







16 Article(s)
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1 32054883 Downregulation of peripheral PTGS2/COX-2 in response to valproate treatment in patients with epilepsy. 2020 Feb 13 2
2 30963442 Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling. 2019 Oct 4
3 28961159 In Vitro Assessment of the Effect of Antiepileptic Drugs on Expression and Function of ABC Transporters and Their Interactions with ABCC2. 2017 Sep 29 2
4 27450623 Interactions between non-vitamin K oral anticoagulants and antiepileptic drugs. 2016 Oct 2
5 24477677 Marked differences in the effect of antiepileptic and cytostatic drugs on the functionality of P-glycoprotein in human and rat brain capillary endothelial cell lines. 2014 Jun 1
6 21316268 Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsy. 2011 Jun 2
7 21388909 Association between ABCB1 polymorphism and response to sodium valproate treatment in Malaysian epilepsy patients. 2011 Mar 3
8 21530324 Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy. 2011 Sep 2
9 20417680 Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients. 2010 Sep 1
10 18165917 Association of MDR1 C3435T polymorphism with bipolar disorder in patients treated with valproic acid. 2009 Mar 2
11 19458058 Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. 2009 Jun 1 1
12 17392393 Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways. 2007 Jul 3
13 17671692 The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells. 2007 Sep 1
14 16894351 The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver. 2006 Oct 3
15 15116123 Valproic acid inhibits proliferation and induces apoptosis in acute myeloid leukemia cells expressing P-gp and MRP1. 2004 Jul 5
16 12954800 Interaction of antiepileptic drugs with human P-glycoprotein in vitro. 2003 Oct 1