| 1 |
34780792 | Overview of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1): Functions, regulation, and structural insights of inhibitors. | 2022 Jan 5 |
2 |
| 2 |
33770316 | Design and development of novel inhibitors of aldo-ketoreductase 1C1 as potential lead molecules in treatment of breast cancer. | 2021 Aug |
2 |
| 3 |
32872468 | Aldo-Keto Reductase 1C1 (AKR1C1) as the First Mutated Gene in a Family with Nonsyndromic Primary Lipedema. | 2020 Aug 29 |
1 |
| 4 |
31333491 | Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism. | 2019 |
4 |
| 5 |
26573806 | Stromal markers AKR1C1 and AKR1C2 are prognostic factors in primary human breast cancer. | 2016 Jun |
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| 6 |
25463305 | Important roles of the AKR1C2 and SRD5A1 enzymes in progesterone metabolism in endometrial cancer model cell lines. | 2015 Jun 5 |
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| 7 |
24390875 | Gender-specific association of variants in the AKR1C1 gene with dimensional anxiety in patients with panic disorder: additional evidence for the importance of neurosteroids in anxiety? | 2014 Oct |
1 |
| 8 |
23183084 | Progestin effects on expression of AKR1C1-AKR1C3, SRD5A1 and PGR in the Z-12 endometriotic epithelial cell line. | 2013 Feb 25 |
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| 9 |
22064385 | Interleukin 1β regulates progesterone metabolism in human cervical fibroblasts. | 2012 Mar |
2 |
| 10 |
22245609 | Expression of human aldo-keto reductase 1C2 in cell lines of peritoneal endometriosis: potential implications in metabolism of progesterone and dydrogesterone and inhibition by progestins. | 2012 May |
1 |
| 11 |
22419909 | Enzymes of the AKR1B and AKR1C Subfamilies and Uterine Diseases. | 2012 |
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| 12 |
21050889 | Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1). | 2011 May |
1 |
| 13 |
21182831 | Progestins as inhibitors of the human 20-ketosteroid reductases, AKR1C1 and AKR1C3. | 2011 May 30 |
5 |
| 14 |
21232532 | Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. | 2011 May 30 |
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| 15 |
21521174 | Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway. | 2011 Jul 1 |
2 |
| 16 |
20727920 | Human 20α-hydroxysteroid dehydrogenase (AKR1C1)-dependent biotransformation with recombinant fission yeast Schizosaccharomyces pombe. | 2010 Oct 1 |
2 |
| 17 |
21217827 | Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses. | 2010 Dec 31 |
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| 18 |
18762229 | Disturbed estrogen and progesterone action in ovarian endometriosis. | 2009 Mar 25 |
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| 19 |
18930784 | Aberrant pre-receptor regulation of estrogen and progesterone action in endometrial cancer. | 2009 Mar 25 |
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| 20 |
18984031 | Progesterone metabolism in adipose cells. | 2009 Jan 27 |
1 |
| 21 |
19007763 | Derivatives of pyrimidine, phthalimide and anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1. | 2009 Mar 16 |
1 |
| 22 |
19320734 | Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival. | 2009 Jul |
1 |
| 23 |
18770491 | AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes. | 2008 Oct |
1 |
| 24 |
18045204 | A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase. | 2007 Nov |
2 |
| 25 |
16962702 | Phytoestrogens as inhibitors of the human progesterone metabolizing enzyme AKR1C1. | 2006 Oct 19 |
2 |
| 26 |
15212687 | Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma. | 2004 Jun 22 |
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| 27 |
15492289 | Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling. | 2004 Oct 15 |
4 |
| 28 |
12604236 | Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone. | 2003 Feb 1 |
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| 29 |
12899831 | Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids. | 2003 Aug 15 |
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| 30 |
11995921 | Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines. | 2002 Apr |
1 |
| 31 |
11306084 | Engineering steroid hormone specificity into aldo-keto reductases. | 2001 Jan 30 |
1 |
| 32 |
10672042 | Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes. | 2000 Feb |
4 |