propargylglycine

cystathionine gamma-lyase ; Homo sapiens







36 Article(s)
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1 31594422 Vasodilator effects of sulforaphane in cerebral circulation: A critical role of endogenously produced hydrogen sulfide and arteriolar smooth muscle KATP and BK channels in the brain. 2020 Oct 1
2 31089421 Endogenous CSE/Hydrogen Sulfide System Regulates the Effects of Glucocorticoids and Insulin on Muscle Protein Synthesis. 2019 2
3 31160338 S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine γ-lyase-dependent hydrogen sulfide synthesis. 2019 Jul 12 3
4 28552745 A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery. 2017 Aug 2
5 27061011 High homocysteine levels prevent via H2 S the CoCl2 -induced alteration of lymphocyte viability. 2016 Aug 1
6 27150157 Endogenous Hydrogen Sulfide Enhances Cell Proliferation of Human Gastric Cancer AGS Cells. 2016 2
7 27313828 S-Propargyl-cysteine Exerts a Novel Protective Effect on Methionine and Choline Deficient Diet-Induced Fatty Liver via Akt/Nrf2/HO-1 Pathway. 2016 2
8 27440715 Hydrogen sulfide contributes to hypoxic inhibition of airway transepithelial sodium absorption. 2016 Sep 1 1
9 24750035 Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone. 2015 Mar 2
10 25543188 Sirtuin 6 is essential for sodium sulfide-mediated cytoprotective effect in ischemia/reperfusion-stimulated brain endothelial cells. 2015 Mar 2
11 25822632 Hydrogen sulfide promotes adipogenesis in 3T3L1 cells. 2015 1
12 26192364 Involvement of hydrogen sulfide in perivascular and hypoxia-induced inhibition of endothelin contraction in porcine retinal arterioles. 2015 Nov 15 4
13 24508802 Endogenous and exogenous hydrogen sulfide facilitates T-type calcium channel currents in Cav3.2-expressing HEK293 cells. 2014 Feb 28 2
14 24707893 The cystathionine γ-lyase/hydrogen sulfide system maintains cellular glutathione status. 2014 Jun 15 2
15 24756435 Inhibition of invasion and epithelial-mesenchymal transition of human breast cancer cells by hydrogen sulfide through decreased phospho-p38 expression. 2014 Jul 1
16 24951966 Statins upregulate cystathionine γ-lyase transcription and H2S generation via activating Akt signaling in macrophage. 2014 Sep 3
17 25113159 Hydrogen sulphide triggers VEGF-induced intracellular Ca²⁺ signals in human endothelial cells but not in their immature progenitors. 2014 Sep 2
18 23393548 Hydrogen sulfide protects HUVECs against hydrogen peroxide induced mitochondrial dysfunction and oxidative stress. 2013 2
19 23704251 Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. 2013 Jun 25 1
20 23733596 L-cysteine and hydrogen sulfide increase PIP3 and AMPK/PPARγ expression and decrease ROS and vascular inflammation markers in high glucose treated human U937 monocytes. 2013 Oct 2
21 22034194 MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells. 2012 Sep 1
22 23074218 Vitamin D up-regulates glucose transporter 4 (GLUT4) translocation and glucose utilization mediated by cystathionine-γ-lyase (CSE) activation and H2S formation in 3T3L1 adipocytes. 2012 Dec 7 2
23 21952317 Hydrogen sulfide contributes to hypoxia-induced radioresistance on hepatoma cells. 2011 4
24 22340158 Electrophysiological effects of hydrogen sulfide on human atrial fibers. 2011 Nov 1
25 20060865 Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-gamma-lyase and upregulation of the transsulfuration pathway in C6 glioma cells. 2010 Mar 1
26 20546998 Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain. 2010 Jul 1
27 19019829 Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S. 2009 Jan 30 3
28 19246614 Production and actions of hydrogen sulfide, a novel gaseous bioactive substance, in the kidneys. 2009 Jun 1
29 19255435 Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. 2009 Mar 17 2
30 18029544 Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery. 2008 Feb 1
31 18679378 Generation of endogenous hydrogen sulfide by cystathionine gamma-lyase limits renal ischemia/reperfusion injury and dysfunction. 2008 Oct 2
32 16230075 Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs. 2005 Oct 1
33 15047144 Impact of hydrogen sulfide on carbon monoxide/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension. 2004 Apr 23 4
34 10212249 Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration. 1999 Apr 30 1
35 16648 Mechanism of inactivation of gamma-cystathionase by the acetylenic substrate analogue propargylglycine. 1977 May 31 1
36 4733835 Acetylenic enzyme inactivators. Inactivation of gamma-cystathionase, in vitro and in vivo, by propargylglycine. 1973 Sep 5 1