Phorbol Esters

proline rich transmembrane protein 2 ; Homo sapiens







227 Article(s)
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1 33502516 PHLPPing the balance: restoration of protein kinase C in cancer. 2021 Jan 29 1
2 30393952 The story of PKC: A discovery marked by unexpected twists and turns. 2019 Jun 1
3 30936203 Heterologous regulation of CXCR4 lysosomal trafficking. 2019 May 17 1
4 28476658 Protein kinase C as a tumor suppressor. 2018 Feb 1
5 28571764 Protein kinase C (PKC) isoforms in cancer, tumor promotion and tumor suppression. 2018 Feb 2
6 29513138 Protein kinase C: perfectly balanced. 2018 Apr 1
7 28112438 Protein kinase C in cancer: The top five unanswered questions. 2017 Jun 1
8 28283201 Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor. 2017 May 3
9 27784766 Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487. 2016 Dec 15 4
10 25619690 Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. 2015 Jan 29 2
11 26021525 Downregulation of BDNF Expression by PKC and by TNF-α in Human Endothelial Cells. 2015 1
12 26717578 Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies. 2015 2
13 23662807 Protein kinase C pharmacology: refining the toolbox. 2013 Jun 1 5
14 24244711 Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor. 2013 1
15 22095874 Contribution of individual PKC isoforms to breast cancer progression. 2012 Jan 2
16 23197040 Protein kinase C, an elusive therapeutic target? 2012 Dec 2
17 21193229 Thapsigargin activates Ca²+ entry both by store-dependent, STIM1/Orai1-mediated, and store-independent, TRPC3/PLC/PKC-mediated pathways in human endothelial cells. 2011 Feb 1
18 21534929 Fine tuning of protein kinase C (PKC) isoforms in cancer: shortening the distance from the laboratory to the bedside. 2011 Mar 2
19 19889850 Dynamic modulation of phasic and asynchronous glutamate release in hippocampal synapses. 2010 Jan 2
20 19228446 Effect of phorbol esters on the macrophage-mediated biodegradation of polyurethanes via protein kinase C activation and other pathways. 2009 2
21 19279008 Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid. 2009 May 8 2
22 19422706 Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility. 2009 May 7 2
23 18473812 Targeting protein kinase C (PKC) in physiology and cancer of the gastric cell system. 2008 1
24 18691117 Potential role of PKC inhibitors in the treatment of hematological malignancies. 2008 1
25 17239975 Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein. 2007 Mar 1
26 17426020 The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 Jun 8 1
27 18067682 Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. 2007 Dec 9 2
28 16607569 Protein kinase C and downstream signaling pathways in a three-dimensional model of phorbol ester-induced angiogenesis. 2006 1
29 16637058 Possible role of duration of PKC-induced ERK activation in the effects of agonists and phorbol esters on DNA synthesis in Panc-1 cells. 2006 Aug 15 1
30 16954220 Invariant Leu preceding turn motif phosphorylation site controls the interaction of protein kinase C with Hsp70. 2006 Oct 27 2
31 19617920 Protein Kinase C Regulates the Cell Surface Activity of Endothelin-Converting Enzyme-1. 2006 Sep 2
32 15703835 PKC-mediated survival signaling in breast carcinoma cells: a role for MEK1-AP1 signaling. 2005 Mar 2
33 15737652 RasGRP3 mediates phorbol ester-induced, protein kinase C-independent exocytosis. 2005 Apr 8 5
34 15986138 Protein kinase C in melanoma. 2005 Jun 2
35 16000638 Dynamic regulation of Na(+)-K(+)-2Cl(-) cotransporter surface expression by PKC-{epsilon} in Cl(-)--secretory epithelia. 2005 Nov 1
36 14720513 Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway. 2004 Jan 1 1
37 15082777 Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation. 2004 May 4
38 15098066 Protein kinase D and keratinocyte proliferation. 2004 Mar 1
39 15213298 PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters. 2004 Jul 1
40 15264216 Nerve growth factor-induced protein kinase C stimulation contributes to TrkA-dependent inhibition of p75 neurotrophin receptor sphingolipid signaling. 2004 Aug 15 1
41 15369389 Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C). 2004 Sep 23 2
42 15381733 Protein kinase C mediates cisplatin-induced loss of adherens junctions followed by apoptosis of renal proximal tubular epithelial cells. 2004 Dec 1
43 15545011 Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway. 2004 1
44 12809530 Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C). 2003 Jun 1
45 12851698 NAMI-A inhibits the PMA-induced ODC gene expression in ECV304 cells: involvement of PKC/Raf/Mek/ERK signalling pathway. 2003 Aug 1
46 14500826 hMSH2 expression is driven by AP1-dependent regulation through phorbol-ester exposure. 2003 Oct 1 1
47 11994357 Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon. 2002 May 1
48 12056641 Protein kinase C involvement in proliferation and survival of breast cancer cells. 2002 1
49 12110518 Stimulation of protein kinase C pathway mediates endocytosis of human nongastric H+-K+-ATPase, ATP1AL1. 2002 Aug 2
50 12183453 Protein kinase C isoforms are translocated to microtubules in neurons. 2002 Oct 25 2