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17719101 | Phosphatidylinositol 4,5-bisphosphate enhances store-operated calcium entry through hTRPC6 channel in human platelets. | 2008 Jan |
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18503745 | Psychotropic drugs interfere with the tight coupling of polyphosphoinositide cycle metabolites in human platelets: a result of receptor-independent drug intercalation in the plasma membrane? | 2008 Oct |
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15447683 | Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2. | 2004 Oct |
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9405283 | Regulation of PtdIns4P 5-kinase C by thrombin-stimulated changes in its phosphorylation state in human platelets. | 1998 Jan 1 |
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9633924 | HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate. | 1998 Jun |
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9726240 | Differential effect of the antidiabetic thiazolidinediones troglitazone and pioglitazone on human platelet aggregation mechanism. | 1998 Sep |
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9795233 | Elevation of cyclic AMP decreases phosphoinositide turnover and inhibits thrombin-induced secretion in human platelets. | 1998 Nov 2 |
2 |
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8573071 | The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin. | 1996 Jan 15 |
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7492569 | Phosphoinositide-specific phospholipase C and mitogenic signaling. | 1995 Dec 18 |
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7926350 | Thrombin-induced platelet aggregation, phosphoinositide metabolism and protein phosphorylation in NIDDM patients treated by diet, sulphonylurea or insulin. | 1994 Jun |
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8042983 | Phosphatidylinositol 3,4,5-trisphosphate is formed from phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets. | 1994 Jul 15 |
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8391903 | [Effect of lipoprotein on phosphatidylinositol -4,5-bisphosphate and phosphatidic acid in platelet]. | 1993 Feb |
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8396627 | U73122 affects the equilibria between the phosphoinositides as well as phospholipase C activity in unstimulated and thrombin-stimulated human and rabbit platelets. | 1993 Sep |
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| 14 |
8400019 | Receptor-mediated signalling pathways acting through hydrolysis of membrane phospholipids in cardiomyocytes. | 1993 Sep |
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1309423 | Endothelium-derived relaxing factor inhibits thrombin-induced platelet aggregation by inhibiting platelet phospholipase C. | 1992 Jan 1 |
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1314112 | Thrombin stimulation of human endothelial cell phospholipase D activity. Regulation by phospholipase C, protein kinase C, and cyclic adenosine 3'5'-monophosphate. | 1992 Apr 15 |
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1647205 | Regulation of the phosphoinositide cycle by Na+/H+ exchange and intracellular pH in human platelets. | 1991 Jun 19 |
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1655398 | Thrombin-induced breakdown of phosphoinositides in platelets from patients with NIDDM. | 1991 Feb |
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| 19 |
1987304 | Hydrogen peroxide alters signal transduction in human endothelial cells. | 1991 Jan |
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2044838 | Stimulation of human platelets with low concentrations of thrombin: evidence for equimolar accumulation of inositol trisphosphates and phosphatidic acid. | 1991 |
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| 21 |
2154447 | Thrombin stimulates the production of a novel polyphosphoinositide in human platelets. | 1990 Feb 15 |
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| 22 |
2159285 | Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells. | 1990 Apr 15 |
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2174010 | Changes in phosphoinositide turnover, Ca2+ mobilization, and protein phosphorylation in platelets from NIDDM patients. | 1990 Dec |
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| 24 |
2537741 | Cyclic nucleotide elevating vasodilators inhibit platelet aggregation at an early step of the activation cascade. | 1989 Jan 17 |
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| 25 |
2539864 | Plasma membrane associated phospholipase C from human platelets: synergistic stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by thrombin and guanosine 5'-O-(3-thiotriphosphate). | 1989 Jan 10 |
4 |
| 26 |
2548908 | Decreased platelet phosphoinositide turnover and enhanced platelet activation in IDDM. | 1989 Sep |
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| 27 |
2845924 | Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism. | 1988 Jul 15 |
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| 28 |
2822018 | Stimulation of polyphosphoinositide hydrolysis by thrombin in membranes from human fibroblasts. | 1987 Jul 1 |
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2822029 | Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin. | 1987 Aug 1 |
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2830631 | Effect of chlorpromazine on inositol-lipid signalling system in human thrombocytes. | 1987 |
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| 31 |
3026850 | Inhibition of Na+/H+ exchange reduces Ca2+ mobilization without affecting the initial cleavage of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets. | 1987 Feb 9 |
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3032933 | Thrombin- and nucleotide-activated phosphatidylinositol 4,5-bisphosphate phospholipase C in human platelet membranes. | 1987 Apr 25 |
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3036588 | Phosphoinositide metabolism in resting and thrombin-stimulated human platelets. Evidence against metabolic heterogeneity. | 1987 Jun 22 |
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3115311 | Signal transduction in normal and pathological thrombin-stimulated human platelets. | 1987 Apr |
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3011769 | Dissociation of Ca2+ mobilization from breakdown of phosphatidylinositol 4,5-bisphosphate in activated human platelets. | 1986 Apr |
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| 36 |
3018731 | Inositol cyclic triphosphate [inositol 1,2-(cyclic)-4,5-triphosphate] is formed upon thrombin stimulation of human platelets. | 1986 Sep |
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| 37 |
3023367 | Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet activation and comparisons with the adenylate cyclase inhibitory protein, Gi. | 1986 Dec 25 |
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3026339 | Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets. | 1986 Aug 15 |
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| 39 |
3755042 | Kinetic differences between thrombin-induced and ADP-induced calcium influx and release from internal stores in fura-2-loaded human platelets. | 1986 May 14 |
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| 40 |
2412047 | Serotonin release and phosphoinositide breakdown in thrombin-induced activation of human platelets. | 1985 |
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| 41 |
2987951 | Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidylinositol 4,5-bisphosphate hydrolysis in human platelets. | 1985 Jun |
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| 42 |
2990473 | Activation of human platelets by ADP causes a rapid rise in cytosolic free calcium without hydrolysis of phosphatidylinositol-4,5-bisphosphate. | 1985 Jun 28 |
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2997707 | Molecular membrane organization in normal and pathological platelets: changes in inositide metabolism and membrane fluidity. | 1985 |
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| 44 |
2999166 | Effects of EGF and thrombin on inositol-containing phospholipids of cultured fibroblasts: stimulation of phosphatidylinositol synthesis by thrombin but not EGF. | 1985 Dec |
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3874867 | Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. Inhibitory effects of phorbol ester. | 1985 Jul 25 |
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| 46 |
6324792 | Phosphatidylinositol 4,5-bisphosphate may represent the site of release of plasma membrane-bound calcium upon stimulation of human platelets. | 1984 Apr 16 |
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6525180 | Inositol lipids, phosphatidate and diacylglycerol share stearoylarachidonoylglycerol as a common backbone in thrombin-stimulated human platelets. | 1984 Dec 15 |
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| 48 |
6296123 | Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets. | 1983 Feb 25 |
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| 49 |
6301436 | The rapid polyphosphoinositide metabolism may be a triggering event for thrombin-mediated stimulation of human platelets. | 1983 Jan 14 |
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