Arachidonic Acid

coagulation factor II, thrombin ; Homo sapiens







200 Article(s)
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51 7624839 Chloroquine inhibits stimulated platelets at the arachidonic acid pathway. 1995 Mar 15 1
52 7717176 Activation of endothelial guanylate cyclase inhibits cellular reactivity. 1995 1
53 7782348 Differential activation of cytosolic phospholipase A2 (cPLA2) by thrombin and thrombin receptor agonist peptide in human platelets. Evidence for activation of cPLA2 independent of the mitogen-activated protein kinases ERK1/2. 1995 Jun 16 1
54 21043769 Original Article: Albumin Prevents TxB, Formation from Thrombin-stimulated Human Platelets by Sequestering the Liberated Arachidonic Acid in the Extracellular Space. 1995 1
55 7822242 Differences related to the production of arachidonic acid between collagen- and thrombin-stimulated human platelets. 1994 Aug 4
56 7878644 The tyrosine kinase inhibitors, genistein and methyl 2,5-dihydroxycinnamate, inhibit the release of (3H)arachidonate from human platelets stimulated by thrombin or collagen. 1994 Oct 1
57 7923307 In vitro effects of trapidil on fatty acid and prostaglandin metabolism in platelets. 1994 May-Jun 2
58 8062861 Bradykinin and thrombin stimulate release of arachidonic acid and formation of prostanoids in human periodontal ligament cells. 1994 Jun 3
59 8195211 Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets. 1994 Jun 3 3
60 8294438 Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation. 1994 Jan 21 1
61 8297360 Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets: possible involvement in late arachidonic acid release. 1994 Jan 28 2
62 8219005 Cloricromene inhibits G-protein-mediated activation of phospholipase A2 in human platelets. 1993 Jul 1
63 8253817 Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human platelets. 1993 Dec 15 2
64 8392344 Effects of dilazep on platelet functions and volume change in patients with diabetes mellitus. 1993 May 1
65 1287888 Arachidonate transfer between platelets and lipoproteins. 1992 Dec 7 1
66 1315576 Activation of phospholipase A2 and beta-thromboglobulin release in human platelets: comparative effects of thrombin and fluoroaluminate stimulation. 1992 Mar 25 3
67 1654060 Sodium fluoride induces phosphoinositide hydrolysis, Ca2+ mobilization, and prostacyclin synthesis in cultured human endothelium: further evidence for regulation by a pertussis toxin-insensitive guanine nucleotide-binding protein. 1991 Aug 1
68 1655146 Thrombin-activated platelets promote leukotriene B4 synthesis in polymorphonuclear leucocytes stimulated by physiological agonists. 1991 Aug 1
69 1710933 Protein kinase C and cyclic AMP modulate thrombin-induced platelet-activating factor synthesis in human endothelial cells. 1991 Jun 7 1
70 1905965 Effects of chlorpromazine on phosphatidylinositol turnover following thrombin stimulation of human platelets. 1991 May 15 1
71 2105325 Thrombin-induced prostacyclin biosynthesis in human endothelium: role of guanine nucleotide regulatory proteins in stimulus/coupling responses. 1990 Jan 1
72 2111085 The coumarin derivative AD6 inhibits the release of arachidonic acid by interfering with phospholipase A2 activity in human platelets stimulated with thrombin. 1990 Mar 2
73 2111540 Deficient collagen-induced activation in the newborn platelet. 1990 Apr 1
74 2111711 Mobilization of arachidonic acid in thrombin-stimulated human platelets. 1990 Feb 1
75 2118426 Effects of acrolein on human platelet aggregation. 1990 1
76 2154180 Extracellular Na+, but not Na+/H+ exchange, is necessary for receptor-mediated arachidonate release in platelets. 1990 Jan 1 2
77 2172436 Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils. 1990 Nov 1 1
78 21043947 Increase in membrane cholesterol content enhances phospholipase a(2) activity and endoperoxide receptor response in human platelets. 1990 1
79 2477083 Human leukocyte cathepsin G and elastase specifically suppress thrombin-induced prostacyclin production in human endothelial cells. 1989 Oct 1
80 2512674 Failure of preactivated human blood platelets to restore defective thromboxane synthesis despite prolonged incubation in plasma. 1989 Nov 24 2
81 2516743 Metabolism of endogenous arachidonic acid in weakly activated platelets. Absence of leukocyte cooperative products in whole blood. 1989 1
82 2521636 Effect of dexamethasone on prostaglandin synthesis and on lipocortin status in human endothelial cells. Inhibition of prostaglandin I2 synthesis occurring without alteration of arachidonic acid liberation and of lipocortin synthesis. 1989 Feb 25 2
83 2538134 Physiological functions of platelets. 1989 Feb 1
84 2553753 Heat shock stimulates the release of arachidonic acid and the synthesis of prostaglandins and leukotriene B4 in mammalian cells. 1989 Nov 1
85 2557075 Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells. 1989 Dec 18 1
86 2559279 Inhibitory effect of stearidonic acid (18:4 n-3) on platelet aggregation and arachidonate oxygenation. 1989 Dec 1
87 2571198 Differences among beta-adrenoceptor blocking drugs in modifying platelet aggregation and arachidonic acid liberation under thrombin stimulation. 1989 Jun 15 2
88 2618870 Role of anions in platelet intra cellular calcium ion rise and arachidonic acid release induced by thrombin. 1989 1
89 2621419 Albumin redirects platelet eicosanoid metabolism toward 12(S)-hydroxyeicosatetraenoic acid. 1989 Dec 1
90 2802631 Substrate specificity of the agonist-stimulated release of polyunsaturated fatty acids from vascular endothelial cells. 1989 Nov 1 1
91 2830284 A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets. 1988 Mar 5 1
92 2831864 Role of phosphoinositides in the regulation of endothelial prostacyclin production. 1988 Mar-Apr 1
93 2840908 Effects of two methylxanthines, pentoxifylline and propentofylline, on arachidonic acid metabolism in platelets stimulated by thrombin. 1988 Sep 1 2
94 2840967 The inhibition of arachidonic acid mobilization in human platelets by R59 022, a diacylglycerol kinase inhibitor. 1988 Aug 12 2
95 2851765 [Effects of pentoxifylline and propentofylline on the turnover of polyphosphoinositides of the erythrocyte membrane and on the metabolism of arachidonic acid in platelets]. 1988 Oct 1
96 3048420 [Lipopolysaccharide-induced hydrolysis of plasmalogenic phosphatidylethanolamine in human platelets]. 1988 May 1
97 3132162 No direct correlation between Ca2+ mobilization and dissociation of Gi during platelet phospholipase A2 activation. 1988 May 31 3
98 3132463 Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor. 1988 Jul 5 1
99 3137235 Release of arachidonic acid from vascular endothelial cells: fatty acyl specificity is observed with receptor-mediated agonists and with the calcium ionophore A23187 but not with melittin. 1988 Aug 1
100 3140902 Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets? 1988 Oct 28 3