Fura-2

coagulation factor II, thrombin ; Homo sapiens







61 Article(s)
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1 26450366 Nicergoline inhibits human platelet Ca(2+) signalling through triggering a microtubule-dependent reorganization of the platelet ultrastructure. 2016 Jan 1
2 26434503 Conventional protein kinase C isoforms differentially regulate ADP- and thrombin-evoked Ca²⁺ signalling in human platelets. 2015 Dec 1
3 21051874 Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study. 2011 1
4 18478545 Ca2+ mobilization mediated by transient receptor potential canonical 3 is associated with thrombin-induced morphological changes in 1321N1 human astrocytoma cells. 2008 Sep 1
5 16095882 Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. 2006 Mar 1
6 12944324 Differential Ca2+ signaling by thrombin and protease-activated receptor-1-activating peptide in human brain microvascular endothelial cells. 2004 Jan 1
7 15016832 Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. 2004 May 14 1
8 15183114 Inactivation of protease-activated receptor-1 by proteolytic removal of the ligand region in vascular endothelial cells. 2004 Jul 1 1
9 12522081 Unproductive cleavage and the inactivation of protease-activated receptor-1 by trypsin in vascular endothelial cells. 2003 Jan 1
10 12908873 Rapid agonist-evoked coupling of type II Ins(1,4,5)P3 receptor with human transient receptor potential (hTRPC1) channels in human platelets. 2003 Nov 1 2
11 11874470 Irregular spiking in free calcium concentration in single, human platelets. Regulation by modulation of the inositol trisphosphate receptors. 2002 Mar 1
12 10686291 Proteolysis and phosphorylation-mediated regulation of thrombin receptor activity in in situ endothelial cells. 2000 Feb 11 1
13 10859594 Simultaneous measurement of intracellular Ca(2+) and nitric oxide: a new method. 2000 May 1
14 11139441 Thrombin causes endothelium-dependent biphasic regulation of vascular tone in the porcine renal interlobar artery. 2000 Dec 1
15 10064008 Secreted dense granule adenine nucleotides promote calcium influx and the maintenance of elevated cytosolic calcium levels in stimulated human platelets. 1999 Feb 1
16 10509892 Serotonin stimulation of calcium mobilisation in human platelets: choice of units of measurement, effects of age and tobacco use, and correlation with serotonin2A receptor density. 1999 Sep 1
17 9720762 The sulphydryl oxidizing reagent diamide affects phosphoinositide-mediated signal transduction: implications for the pathogenesis of Alzheimer's disease. 1998 Jun 1
18 9722316 Inter-individual variability in Ca2+ signalling in platelets from healthy volunteers: effects of aspirin and relationship with expression of endomembrane Ca2+-ATPases. 1998 Aug 1
19 9374730 Mechanisms underlying TNF-alpha effects on agonist-mediated calcium homeostasis in human airway smooth muscle cells. 1997 Nov 1
20 9385466 Calibration of Fura-2 signals introduces errors into measurement of thrombin-stimulated calcium mobilisation in human platelets. 1997 Sep 30 3
21 8848347 Impaired mobilization of intracellular calcium in neonatal platelets. 1996 Apr 1
22 8897698 The inhibitory effect of 2-thienyl 2'-hydroxyphenyl ketone (C85) on platelet thromboxane formation. 1996 Oct 15 1
23 7554143 Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. 1995 Nov 1
24 7635245 Pharmacological properties of MM-706, a new prostacyclin derivative. 1995 Jul 1
25 8091392 Serum lipid profile determines platelet reactivity to native and modified LDL-cholesterol in humans. 1994 May 1
26 8206566 Blood pressure inversely correlates with thrombin-evoked calcium rise in platelets. 1994 Jun 1
27 8220881 Effects of L- and D-arginine and some related esters on the cytosolic mechanisms of alpha-thrombin-induced human platelet activation. 1993 Sep 1
28 8392939 Influence of the cGMP analog 8-PCPT-cGMP on agonist-induced increases in cytosolic ionized Ca2+ and on aggregation of human platelets. 1993 May 15 1
29 8420790 Effects of nitric oxide-containing compounds on increases in cytosolic ionized Ca2+ and on aggregation of human platelets. 1993 Jan 4 1
30 8422913 The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets. 1993 Jan 11 1
31 8510321 Effects of 3 aminoglycoside antibiotics (kanamycin, gentamicin and fradiomycin) on the thrombin-induced aggregation and intracellular Ca2+ mobilization of human platelets. 1993 Mar 2
32 1309423 Endothelium-derived relaxing factor inhibits thrombin-induced platelet aggregation by inhibiting platelet phospholipase C. 1992 Jan 1 2
33 1324922 Two thrombin-activated Ca2+ channels in human platelets. 1992 Aug 25 1
34 1527727 Thrombin, but not thromboxane, stimulates megakaryocytic differentiation in human megakaryoblastic leukemia cells. 1992 Sep 1
35 1592099 Transient calcium elevation in polymorphonuclear leukocytes triggered by thrombin-activated platelets. 1992 Apr 1
36 1737761 Rapid ADP-evoked currents in human platelets recorded with the nystatin permeabilized patch technique. 1992 Feb 15 2
37 1900287 Thrombin attenuates the stimulatory effect of histamine on Ca2+ entry in confluent human umbilical vein endothelial cell cultures. 1991 Mar 5 1
38 2015414 Thrombin increases cytoplasmic Ca2+ and stimulates formation of prostaglandin E2 in the osteoblastic cell line MC3T3-El. 1991 Feb 1
39 2168700 Ligands to the platelet fibrinogen receptor glycoprotein IIb-IIIa do not affect agonist-induced second messengers Ca2+ or cyclic AMP. 1990 Aug 15 2
40 2175792 Octimibate inhibition of platelet aggregation: stimulation of adenylate cyclase through prostacyclin receptor activation. 1990 Dec 1
41 2338678 Basal and stimulated cytosolic platelet calcium in essential hypertension. 1990 Apr 1
42 2383431 Influence of nitric oxide on agonist-mediated calcium mobilization in platelets. 1990 Jun 1
43 2499358 Evidence of Ca2+ mobilizing action of arachidonic acid in human platelets. 1989 Jun 15 1
44 2730577 Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+. 1989 Mar 15 2
45 2777805 Nature of thrombin-induced sustained increase in cytosolic calcium concentration in cultured endothelial cells. 1989 Oct 5 1
46 2829732 Ethanol stimulates shape change in human platelets by activation of phosphoinositide-specific phospholipase C. 1988 Jan 1
47 3063257 Action of guanosine 5'-[beta-thio]diphosphate on thrombin-induced activation and Ca2+ mobilization in saponin-permeabilized and intact human platelets. 1988 Nov 1 2
48 3196311 Evidence that agonists stimulate bivalent-cation influx into human endothelial cells. 1988 Oct 1 1
49 3260903 Thrombin and histamine activate phospholipase C in human endothelial cells via a phorbol ester-sensitive pathway. 1988 Jul 1
50 3347929 Inhibition by the antilipogenic antibiotic cerulenin of thrombin-induced activation of human platelets. 1988 Jan 1 1