| 51 |
21067431 | Accelerated fracture healing in mice lacking the 5-lipoxygenase gene. | 2010 Dec |
1 |
| 52 |
18804760 | Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice. | 2009 Apr |
2 |
| 53 |
19573621 | Lipid bodies in oxidized LDL-induced foam cells are leukotriene-synthesizing organelles: a MCP-1/CCL2 regulated phenomenon. | 2009 Nov |
1 |
| 54 |
19776641 | Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics. | 2009 |
1 |
| 55 |
20091263 | (-)-Nyasol (cis-hinokiresinol), a norneolignan from the rhizomes of Anemarrhena asphodeloides, is a broad spectrum inhibitor of eicosanoid and nitric oxide production. | 2009 Nov |
2 |
| 56 |
17998412 | 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease. | 2008 Apr |
1 |
| 57 |
18004232 | Leukotriene B4/leukotriene B4 receptor pathway is involved in hepatic microcirculatory dysfunction elicited by endotoxin. | 2008 Jul |
4 |
| 58 |
18048478 | 5-Lipoxygenase-derived lipid mediators are not required for the development of NSAID-induced inflammatory bowel disease in IL-10-/- mice. | 2008 Feb |
1 |
| 59 |
18059327 | Effects of zileuton and montelukast in mouse experimental spinal cord injury. | 2008 Feb |
1 |
| 60 |
18336255 | Mast cells and inflammatory heart disease: potential drug targets. | 2008 Mar |
1 |
| 61 |
17334599 | The role of 5-lipoxygenase and leukotrienes in shock and ischemia-reperfusion injury. | 2007 Jan 22 |
2 |
| 62 |
17347013 | Inhibition of leukotriene biosynthesis abrogates the host control of Mycobacterium tuberculosis. | 2007 Apr |
1 |
| 63 |
17392829 | Selective 5-lipoxygenase expression in Langerhans cells and impaired dendritic cell migration in 5-LO-deficient mice reveal leukotriene action in skin. | 2007 Jul |
3 |
| 64 |
17397875 | Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice. | 2007 Apr 24 |
1 |
| 65 |
17586489 | Role of 5-lipoxygenase in myocardial ischemia-reperfusion injury in mice. | 2007 Sep 24 |
1 |
| 66 |
16489117 | Involvement of GATA-3-dependent Th2 lymphocyte activation in airway hyperresponsiveness. | 2006 Jun |
1 |
| 67 |
16506957 | Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice. | 2006 Mar |
1 |
| 68 |
16624488 | Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma. | 2006 Jul |
1 |
| 69 |
17182931 | Is there a role for the macrophage 5-lipoxygenase pathway in aortic aneurysm development in apolipoprotein E-deficient mice? | 2006 Nov |
1 |
| 70 |
20477620 | Lipoxygenase and prostaglandin G/H synthase cascades in cardiovascular disease. | 2006 Jul |
3 |
| 71 |
15661924 | Opposing and hierarchical roles of leukotrienes in local innate immune versus vascular responses in a model of sepsis. | 2005 Feb 1 |
2 |
| 72 |
15821759 | 5-Lipoxygenase modulates colitis through the regulation of adhesion molecule expression and neutrophil migration. | 2005 Jun |
1 |
| 73 |
15894604 | 5-Lipoxygenase deficiency prevents respiratory failure during ventilator-induced lung injury. | 2005 Aug 1 |
1 |
| 74 |
16046553 | Up-regulation of prostaglandin biosynthesis by leukotriene C4 in elicited mice peritoneal macrophages activated with lipopolysaccharide/interferon-{gamma}. | 2005 Oct |
1 |
| 75 |
16081317 | The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis. | 2005 Sep 5 |
2 |
| 76 |
15223810 | Endotoxin-induced uveitis in cyclooxygenase-2-deficient mice. | 2004 Jul |
1 |
| 77 |
15322539 | The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. | 2004 Sep |
1 |
| 78 |
15328042 | Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase. | 2004 Sep 17 |
2 |
| 79 |
15353362 | Non-prostaglandin eicosanoids in fever and anapyrexia. | 2004 Sep 1 |
1 |
| 80 |
15361791 | Mechanisms of leukocyte recruitment to atherosclerotic lesions: future prospects. | 2004 Oct |
1 |
| 81 |
12730086 | Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis-resistance mice confer impaired activity when introduced into the human ortholog. | 2003 Jun 1 |
1 |
| 82 |
11919084 | Cloning and functional analysis of the mouse 5-lipoxygenase promoter. | 2002 Apr |
2 |
| 83 |
12021253 | Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo. | 2002 May |
1 |
| 84 |
12142344 | Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. | 2002 Jul 26 |
1 |
| 85 |
12237493 | 5-lipoxygenase (5LOX)-deficient mice express reduced anxiety-like behavior. | 2002 |
2 |
| 86 |
11160610 | Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid and identification of novel omega-oxidized metabolites in the mouse macrophage. | 2001 Feb |
1 |
| 87 |
11254552 | Leukotriene B4 augments neutrophil phagocytosis of Klebsiella pneumoniae. | 2001 Apr |
1 |
| 88 |
11451994 | Modulation of cell-substrate adhesion by arachidonic acid: lipoxygenase regulates cell spreading and ERK1/2-inducible cyclooxygenase regulates cell migration in NIH-3T3 fibroblasts. | 2001 Jul |
1 |
| 89 |
11518028 | Effects of furocoumarins from Cachrys trifida on some macrophage functions. | 2001 Aug |
1 |
| 90 |
11714834 | Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice. | 2001 Dec 1 |
1 |
| 91 |
10779800 | Genetic factors determine the contribution of leukotrienes to acute inflammatory responses. | 2000 May 1 |
1 |
| 92 |
11082424 | Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97). | 2000 Dec |
1 |
| 93 |
10384136 | Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice. | 1999 Jul 1 |
1 |
| 94 |
10514459 | Identification of a bipartite nuclear localization sequence necessary for nuclear import of 5-lipoxygenase. | 1999 Oct 15 |
3 |
| 95 |
10586081 | Determination of the contribution of cysteinyl leukotrienes and leukotriene B4 in acute inflammatory responses using 5-lipoxygenase- and leukotriene A4 hydrolase-deficient mice. | 1999 Dec 15 |
1 |
| 96 |
9744535 | Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents. | 1998 Aug |
1 |
| 97 |
9091580 | Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses. | 1997 Mar 17 |
1 |
| 98 |
8915769 | Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo. | 1996 Nov |
1 |
| 99 |
8955165 | Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumonia in association with decreased alveolar macrophage phagocytic and bactericidal activities. | 1996 Dec 15 |
2 |
| 100 |
7969451 | Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. | 1994 Nov 10 |
1 |