Cyclosporine

CD28 molecule ; Homo sapiens







54 Article(s)
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1 35553638 COPD is associated with increased pro-inflammatory CD28null CD8 T and NKT-like cells in the small airways. 2022 May 12 1
2 33317956 Bronchiolitis obliterans syndrome is associated with increased senescent lymphocytes in the small airways. 2021 Feb 1
3 26144210 Synthesis and Bioactivity of a Brasilicardin A Analogue Featuring a Simplified Core. 2015 Jul 17 1
4 18606654 FOXP3 induced by CD28/B7 interaction regulates CD25 and anergic phenotype in human CD4+CD25- T lymphocytes. 2008 Jul 15 1
5 18617642 CD28 down-regulation on CD4 T cells is a marker for graft dysfunction in lung transplant recipients. 2008 Oct 1 2
6 18845086 [Regulatory function of tacrolimus and CsA on CD4/CD8 T lymphocyte subgroups and costimulators on them in allo-liver recipients]. 2008 Oct 1
7 15710339 Cyclosporin A inhibits the early phase of NF-kappaB/RelA activation induced by CD28 costimulatory signaling to reduce the IL-2 expression in human peripheral T cells. 2005 Apr 6
8 16044165 Pharmacologic profiling of transcriptional targets deciphers promoter logic. 2005 1
9 14709642 Sensitivity of whole-blood T lymphocytes in individual patients to tacrolimus (FK 506): impact of interleukin-2 mRNA expression as surrogate measure of immunosuppressive effect. 2004 Jan 1
10 15459204 Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17. 2004 Dec 10 1
11 15501456 Curcumin inhibits mitogen stimulated lymphocyte proliferation, NFkappaB activation, and IL-2 signaling. 2004 Oct 1
12 12744774 Individual variability in cyclosporin A sensitivity: the assessment of functional measures on CD28-mediated costimulation of human whole blood T lymphocytes. 2003 Feb 2
13 11981427 Mechanisms of targeting CD28 by a signaling monoclonal antibody in acute and chronic allograft rejection. 2002 Apr 27 1
14 12036883 Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. 2002 Jun 15 5
15 12097397 Human neutrophil-expressed CD28 interacts with macrophage B7 to induce phosphatidylinositol 3-kinase-dependent IFN-gamma secretion and restriction of Leishmania growth. 2002 Jul 15 3
16 11357886 Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro. 2001 Apr 2
17 21336903 Collection, separation, and activation of human T lymphocytes. 2001 1
18 10760803 CD28 and LFA-1 contribute to cyclosporin A-resistant T cell growth by stabilizing the IL-2 mRNA through distinct signaling pathways. 2000 Apr 1
19 10928971 FK506 potently inhibits T cell activation induced TNF-alpha and IL-1beta production in vitro by human peripheral blood mononuclear cells. 2000 Aug 3
20 11093160 The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes. 2000 Dec 1
21 10202558 The complexities of CD28 and CTLA-4 signalling: PI3K and beyond. 1999 1
22 10589954 Human T cell responses to human and porcine endothelial cells are highly sensitive to cyclosporin A and FK506 in vitro. 1999 Nov 27 2
23 9603452 Cyclosporin A increases IFN-gamma production by T cells when co-stimulated through CD28. 1998 May 2
24 9640246 Simultaneous cross-linking of CD6 and CD28 induces cell proliferation in resting T cells. 1998 Mar 2
25 9733605 Curcumin blocks cyclosporine A-resistant CD28 costimulatory pathway of human T-cell proliferation. 1998 Jul 1 1
26 9548474 T cell stimulation via CD47: agonistic and antagonistic effects of CD47 monoclonal antibody 1/1A4. 1997 Dec 1 1
27 8596025 Differential regulation of bcl-2 and bcl-x by CD3, CD28, and the IL-2 receptor in cloned CD4+ helper T cells. A model for the long-term survival of memory cells. 1996 Mar 1 1
28 8631809 Activation of nuclear factor of activated T cells in a cyclosporin A-resistant pathway. 1996 Mar 29 2
29 8757955 Primary porcine endothelial cells express membrane-bound B7-2 (CD86) and a soluble factor that co-stimulate cyclosporin A-resistant and CD28-dependent human T cell proliferation. 1996 Jul 2
30 8809021 CD28: a signalling perspective. 1996 Sep 1 1
31 7534790 CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses. 1995 Apr 1 1
32 7634349 Crosslinking of CD27 in the presence of CD28 costimulation results in T cell proliferation and cytokine production. 1995 Aug 1
33 7506079 Synergy between cyclosporin A and a monoclonal antibody to B7 in blocking alloantigen-induced T-cell activation. 1994 Jan 1 1
34 7507511 The combination of anti-B7 monoclonal antibody and cyclosporin A induces alloantigen-specific anergy during a primary mixed lymphocyte reaction. 1994 Feb 1 1
35 7515910 Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction. 1994 Jun 15 1
36 7516408 Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. 1994 Jul 1 1
37 7524221 Individual susceptibility to cyclosporine: possible involvement of the CD28/CD80 (B7/BB1) pathway. 1994 Oct 1
38 7878594 Individual differences in the in vitro response to cyclosporin A (CsA): possible heterogeneity in the involvement of the CD28-B7/BB1 pathway. 1994 May-Jun 1
39 7957566 CD28 signal transduction: tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activity. 1994 Nov 1
40 7982907 CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin. 1994 Dec 2 2
41 8077662 Induction of IL-8 expression in T cells uses the CD28 costimulatory pathway. 1994 Sep 15 1
42 8183372 Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. 1994 May 26 1
43 8302298 Functional expression of human CD28 in murine T cell hybridomas. 1994 Jan 1
44 7682237 CD28 ligation by monoclonal antibodies or B7/BB1 provides an accessory signal for the cyclosporin A-resistant generation of cytotoxic T cell activity. 1993 Apr 15 2
45 1348520 CD28-stimulated IL-2 gene expression in Jurkat T cells occurs in part transcriptionally and is cyclosporine-A sensitive. 1992 Apr 15 2
46 1646506 The effect of the CD28 activation pathway on the immunosuppressive action of cyclosporine. 1991 Jun 6
47 1676547 Activation of peripheral CD8+ T lymphocytes via CD28 plus CD2: evidence for IL-2 gene transcription mediated by CD28 activation. 1991 Jan 2
48 1705509 Immobilized anti-CD5 together with prolonged activation of protein kinase C induce interleukin 2-dependent T cell growth: evidence for signal transduction through CD5. 1991 Feb 1
49 1847252 Evidence that genistein, a protein-tyrosine kinase inhibitor, inhibits CD28 monoclonal-antibody-stimulated human T cell proliferation. 1991 Feb 5
50 2465550 CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. 1989 Feb 2