Tretinoin

PML nuclear body scaffold ; Homo sapiens







275 Article(s)
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151 15234573 Alteration in the cellular response to retinoic acid of a human acute promyelocytic leukemia cell line, UF-1, carrying a patient-derived mutant PML-RARalpha chimeric gene. 2004 Sep 7
152 15319284 Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors. 2004 Dec 15 3
153 15358589 Molecular mechanisms of chemoprevention and therapy of cancer by retinoids. 2004 Sep 1 1
154 15512805 Signalling pathways activated by all-trans-retinoic acid in acute promyelocytic leukemia cells. 2004 Nov 2
155 12642121 The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease. 2003 Jun 1
156 12647219 Expression of promyelocytic leukemia protein increases during the differentiation of human neuroblastoma cells. 2003 Mar 1
157 12769347 Retinoic acid induction of CD38 antigen expression on normal and leukemic human myeloid cells: relationship with cell differentiation. 2003 Apr 1
158 12773567 PML colocalizes with and stabilizes the DNA damage response protein TopBP1. 2003 Jun 1
159 12821942 The cleavage product deltaPML-RARalpha contributes to all-trans retinoic acid-mediated differentiation in acute promyelocytic leukemia cells. 2003 Jun 26 7
160 12893766 Comparative analysis of genes regulated by PML/RAR alpha and PLZF/RAR alpha in response to retinoic acid using oligonucleotide arrays. 2003 Nov 15 1
161 12895391 Monitoring PML-RARalpha in acute promyelocytic leukemia. 2003 Sep 1
162 12970771 Retinoid target genes in acute promyelocytic leukemia. 2003 Sep 2
163 14597990 PML/RARalpha plays a role for basal activity and retinoid-induced repression of the tissue factor promoter in acute promyelocytic leukemia cells. 2003 Nov 2
164 14706140 [Improved RT-PCR for detection of PML/RARalpha fusion gene in rapid diagnosis of acute promyelocytic leukemia]. 2003 Dec 3
165 27265573 Quantification of All-Trans-Retinoic Acid (ATRA) Dependent Expression of CXCR4 Gene in Acute Promyelocytic Leukaemia. 2003 Sep 5 1
166 11682484 ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells. 2002 Jan 4 3
167 11788605 Up-regulation of acid sphingomyelinase during retinoic acid-induced myeloid differentiation of NB4, a human acute promyelocytic leukemia cell line. 2002 Mar 22 1
168 11818666 Advances in the treatment of relapsed acute promyelocytic leukemia. 2002 2
169 11830487 Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. 2002 Feb 15 8
170 11891284 UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia. 2002 Mar 19 2
171 11930660 All-trans retinoic acid as a single agent induces complete remission in a patient with acute leukemia of M2a subtype. 2002 Jan 1
172 12015078 [Study of the effects of quercetin on PML gene and protein expression and localization in leukemia cells]. 2002 Feb 1
173 12032336 Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy. 2002 May 28 2
174 12239173 Response to histone deacetylase inhibition of novel PML/RARalpha mutants detected in retinoic acid-resistant APL cells. 2002 Oct 1 3
175 12357342 Finding a role for PML in APL pathogenesis: a critical assessment of potential PML activities. 2002 Oct 2
176 12357343 PML a target of translocations in APL is a regulator of cellular senescence. 2002 Oct 1
177 12357345 Signaling revisited in acute promyelocytic leukemia. 2002 Oct 1
178 11112687 Interferon gamma regulates accumulation of the proteasome activator PA28 and immunoproteasomes at nuclear PML bodies. 2001 Jan 1
179 11133770 Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo. 2001 Jan 1 2
180 11264371 Human neuron-committed teratocarcinoma NT2 cell line has abnormal ND10 structures and is poorly infected by herpes simplex virus type 1. 2001 Apr 1
181 11301322 PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells. 2001 Jun 22 6
182 11342454 Tyrosine kinase inhibitor STI571 potentiates the pharmacologic activity of retinoic acid in acute promyelocytic leukemia cells: effects on the degradation of RARalpha and PML-RARalpha. 2001 May 15 1
183 11438209 Novel mutation in the PML/RARalpha chimeric gene exhibits dramatically decreased ligand-binding activity and confers acquired resistance to retinoic acid in acute promyelocytic leukemia. 2001 Jul 4
184 11681409 Pulsed ATRA as single therapy restores long-term remission in PML-RARalpha-positive acute promyelocytic leukemia patients: real time quantification of minimal residual disease. A pilot study. 2001 Nov 1
185 11699203 Acute promyelocytic leukemia with apparently normal karyotype: molecular findings and response to all-trans retinoic acid. 2001 Jun 2
186 11704843 Arsenic trioxide, a therapeutic agent for APL. 2001 Oct 29 1
187 11704854 Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission. 2001 Oct 29 1
188 11779431 Effect of all-trans retinoic acid and arsenic trioxide on tissue factor expression in acute promyelocytic leukemia cells. 2001 Jan 1
189 27419349 Exogenous PML/RARα Fusion Gene Responds to All-trans Retinoic Acid Results in Differentiation of the Human B Cell Line. 2001 4
190 10637480 The impact of differential binding of wild-type RARalpha, PML-, PLZF- and NPM-RARalpha fusion proteins towards transcriptional co-activator, RIP-140, on retinoic acid responses in acute promyelocytic leukemia. 2000 Jan 2
191 10673742 A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities. 2000 Feb 3
192 10684855 Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. 2000 Feb 21 1
193 10702898 Acute promyelocytic leukemia. From morphology to molecular lesions. 2000 Mar 1
194 10766166 Identification of B94 (TNFAIP2) as a potential retinoic acid target gene in acute promyelocytic leukemia. 2000 Apr 1 3
195 10865965 Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation. APL Study Group. Acute promyelocytic leukemia. 2000 Jun 1
196 10870476 Current issues in the management of acute promyelocytic leukemia. 2000 May 2
197 11007958 The promyelocytic (PML) nuclear compartment and transcription control. 2000 Oct 15 1
198 11050004 Altered ligand binding and transcriptional regulation by mutations in the PML/RARalpha ligand-binding domain arising in retinoic acid-resistant patients with acute promyelocytic leukemia. 2000 Nov 1 2
199 11389537 Alterations in subnuclear trafficking of nuclear regulatory factors in acute leukemia. 2000 1
200 11798775 [Effects of arsenic trioxide on K562 cells stably expressing two promyelocytic leukemia-specific fusion proteins]. 2000 Apr 1