| 1 |
35622143 | PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As2O3 by stabilizing oncoprotein PML-RARα. | 2022 May 27 |
1 |
| 2 |
32854112 | A PML/RARα direct target atlas redefines transcriptional deregulation in acute promyelocytic leukemia. | 2021 Mar 18 |
1 |
| 3 |
33901013 | C/EBPα is indispensable for PML/RARα-mediated suppression of long non-coding RNA NEAT1 in acute promyelocytic leukemia cells. | 2021 Apr 26 |
2 |
| 4 |
33957999 | Current views on the genetic landscape and management of variant acute promyelocytic leukemia. | 2021 May 6 |
1 |
| 5 |
34047175 | A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia. | 2021 Dec 1 |
3 |
| 6 |
34405393 | PML-RARA transcript levels at the end of induction therapy are associated with prognosis in non-high-risk acute promyelocytic leukaemia with all-trans retinoic acid plus arsenic in front-line therapy: long-term follow-up of a single-centre cohort study. | 2021 Dec |
1 |
| 7 |
31654721 | NLS-RARα contributes to differentiation block and increased leukemogenic potential in vivo. | 2020 Jan |
1 |
| 8 |
32036017 | Nuclear import of NLS- RARα is mediated by importin α/β. | 2020 May |
1 |
| 9 |
32274275 | Promyelocytic Blast Crisis of Chronic Myeloid Leukemia in a Patient Undergoing Therapy with a Tyrosine Kinase Inhibitor. | 2020 Mar 9 |
1 |
| 10 |
32323584 | Clinical significance of increased PML-RARa transcripts after induction therapy for acute promyelocytic leukaemia. | 2020 Aug |
1 |
| 11 |
32380366 | Treatment outcomes of patients with acute promyelocytic leukaemia between 2000 and 2017, a retrospective, single centre experience. | 2020 Apr 24 |
1 |
| 12 |
32823855 | Emerging Cancer Epigenetic Mechanisms Regulated by All-Trans Retinoic Acid. | 2020 Aug 14 |
1 |
| 13 |
28291070 | FLORID NEOVASCULARIZATION OF THE RETINA IN A DIABETIC PATIENT UNDERGOING INDUCTION AND CONSOLIDATION THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA. | 2019 Spring |
1 |
| 14 |
30536958 | PML/RARA inhibits expression of HSP90 and its target AKT. | 2019 Mar |
2 |
| 15 |
30572725 | Intravenous arsenic trioxide and all-trans retinoic acid as front-line therapy for low-risk acute promyelocytic leukemia. | 2019 Feb |
1 |
| 16 |
30824184 | Identification of a point mutation PMLS214L-RARα that alters PML body organization, dynamics and SUMOylation. | 2019 Apr 9 |
4 |
| 17 |
30876657 | Early treatment of acute promyelocytic leukaemia is accurately guided by the PML protein localisation pattern: real-life experience from a tertiary New Zealand centre. | 2019 Jun |
1 |
| 18 |
30992691 | RNF8 is responsible for ATRA resistance in variant acute promyelocytic leukemia with GTF2I/RARA fusion, and inhibition of the ubiquitin-proteasome pathway contributes to the reversion of ATRA resistance. | 2019 |
1 |
| 19 |
31135261 | PML-RARα induces all-trans retinoic acid-dependent transcriptional activation through interaction with MED1. | 2019 Jun |
5 |
| 20 |
31292998 | Mutational landscape of patients with acute promyelocytic leukemia at diagnosis and relapse. | 2019 Oct |
1 |
| 21 |
31447065 | Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy. | 2019 Sep |
2 |
| 22 |
31592194 | KDM3B suppresses APL progression by restricting chromatin accessibility and facilitating the ATRA-mediated degradation of PML/RARα. | 2019 |
3 |
| 23 |
31905996 | PML/RARa Interferes with NRF2 Transcriptional Activity Increasing the Sensitivity to Ascorbate of Acute Promyelocytic Leukemia Cells. | 2019 Dec 30 |
1 |
| 24 |
28521962 | The functional roles of PML nuclear bodies in genome maintenance. | 2018 May |
1 |
| 25 |
29224413 | Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation. | 2018 |
2 |
| 26 |
29387217 | Effects of lapatinib on cell proliferation and apoptosis in NB4 cells. | 2018 Jan |
2 |
| 27 |
29596829 | Influence of acute promyelocytic leukemia therapeutic drugs on nuclear pore complex density and integrity. | 2018 May 15 |
2 |
| 28 |
29795382 | Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia. | 2018 May 24 |
3 |
| 29 |
29973452 | [Acute promyelocytic leukemia: state-of-the-art management]. | 2018 |
2 |
| 30 |
30026570 | Molecular remission as a therapeutic objective in acute promyelocytic leukemia. | 2018 Aug |
2 |
| 31 |
30114705 | Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/Rarα Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: in Vitro and in Vivo Studies. | 2018 |
1 |
| 32 |
30289902 | Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia. | 2018 |
5 |
| 33 |
30662778 | An Unusual Coexistence of Primary Central Nervous System Non-Hodgkin's Lymphoma and Acute Promyelocytic Leukemia. | 2018 |
1 |
| 34 |
27605212 | Activation of G0S2 is coordinated by recruitment of PML/RARα and C/EBPε to its promoter during ATRA-induced APL differentiation. | 2017 Mar |
8 |
| 35 |
27740626 | The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway. | 2017 Feb |
2 |
| 36 |
28063140 | Regulatory mechanism and functional analysis of S100A9 in acute promyelocytic leukemia cells. | 2017 Mar |
2 |
| 37 |
28129653 | RXRα ligand Z-10 induces PML-RARα cleavage and APL cell apoptosis through disrupting PML-RARα/RXRα complex in a cAMP-independent manner. | 2017 Feb 14 |
2 |
| 38 |
28486108 | TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence. | 2017 May 8 |
2 |
| 39 |
28492552 | All-trans retinoic acid and arsenic trioxide fail to derepress the monocytic differentiation driver Irf8 in acute promyelocytic leukemia cells. | 2017 May 11 |
3 |
| 40 |
28712407 | [Detection and clinical significance of PML protein expression of acute promyelocytic leukemia cells]. | 2017 Jul |
2 |
| 41 |
28766684 | Epigallocatechin-3-gallate promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells via PTEN. | 2017 Sep |
2 |
| 42 |
30695510 | [The Significance of Genetic Testing for Acute Promyelocytic Leukemia]. | 2017 Jan |
2 |
| 43 |
26374632 | PML-RARa modulates the vascular signature of extracellular vesicles released by acute promyelocytic leukemia cells. | 2016 Jan |
2 |
| 44 |
26728337 | Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia. | 2016 Mar |
1 |
| 45 |
26997274 | NPM and BRG1 Mediate Transcriptional Resistance to Retinoic Acid in Acute Promyelocytic Leukemia. | 2016 Mar 29 |
1 |
| 46 |
27133819 | PML-RARα kinetics and impact of FLT3-ITD mutations in newly diagnosed acute promyelocytic leukaemia treated with ATRA and ATO or ATRA and chemotherapy. | 2016 Oct |
2 |
| 47 |
27468685 | PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL. | 2016 Jul 28 |
4 |
| 48 |
27486764 | C-Myc functions as a competing endogenous RNA in acute promyelocytic leukemia. | 2016 Aug 30 |
2 |
| 49 |
27626069 | Evolution of a FLT3-TKD mutated subclone at meningeal relapse in acute promyelocytic leukemia. | 2016 Sep |
1 |
| 50 |
27732960 | Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells. | 2016 Nov 15 |
1 |