tofacitinib

tumor necrosis factor ; Homo sapiens







43 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35081280 Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis. 2022 Jan 27 2
2 35156617 Treatment with biologic DMARDs may not adversely affect lung nodules in rheumatoid arthritis patients. 2022 Apr 1
3 35373565 Clinical settings with tofacitinib in ulcerative colitis. 2022 Apr 4 2
4 35392018 Initial experience of tofacitinib for treating refractory moderate-to-severe ulcerative colitis. 2022 Feb 1
5 35484689 Longitudinal monitoring of STAT3 phosphorylation and histologic outcome of tofacitinib therapy in patients with ulcerative colitis. 2022 Apr 28 1
6 35536531 Tofacitinib enhances IGF1 via inhibiting STAT6 transcriptionally activated-miR-425-5p to ameliorate inflammation in RA-FLS. 2022 May 10 2
7 33165509 Impaired IFN-γ-dependent STAT3 Activation Is Associated With Dysregulation of Regulatory and Inflammatory Signaling in Monocytes of Ulcerative Colitis Patients. 2021 May 17 1
8 33405424 Real-world clinical and endoscopic outcomes after one year tofacitinib treatment in ulcerative colitis. 2021 Oct 1 1
9 33484120 High-Dose Rescue Tofacitinib Prevented Inpatient Colectomy in Acute Severe Ulcerative Colitis Refractory to Anti-TNF. 2021 Apr 15 1
10 33495807 Downregulation of miR‑409‑3p suppresses LPS‑induced inflammation in human bronchial epithelial cells through SOCS3/JAK1/STAT3 signaling: The implication for bronchopneumonia. 2021 Mar 1
11 33835018 Comparative efficacy and safety of secukinumab, ixekizumab, and tofacitinib in patients with active psoriatic arthritis showing insufficient response to tumor necrosis factor inhibitors. 2021 Jul 1
12 33899926 Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis. 2021 Aug 2
13 34052462 The JAK inhibitor Tofacitinib inhibits structural damage in osteoarthritis by modulating JAK1/TNF-alpha/IL-6 signaling through Mir-149-5p. 2021 Oct 2
14 34907436 Trend in Prescription and Treatment Retention of Molecular-Targeted Drugs in 121,131 Japanese Patients With Rheumatoid Arthritis: A Population-Based Real-World Study. 2021 Dec 15 2
15 31560043 Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype. 2020 Feb 11 1
16 31813060 Tofacitinib for the treatment for colchicine-resistant familial Mediterranean fever: case-based review. 2020 Jan 1
17 31916703 Treatment of Multiorgan Sarcoidosis With Tofacitinib. 2020 Feb 1
18 31945470 First- and Second-Line Pharmacotherapies for Patients With Moderate to Severely Active Ulcerative Colitis: An Updated Network Meta-Analysis. 2020 Sep 4
19 32237087 Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry. 2020 May 1
20 32922513 Infliximab, adalimumab, golimumab, vedolizumab and tofacitinib in moderate to severe ulcerative colitis: comparative cost-effectiveness study in Poland. 2020 1
21 30734234 Real-World Experience with Tofacitinib in IBD at a Tertiary Center. 2019 Jul 1
22 31284768 Tofacitinib inhibits ox-LDL-induced adhesion of THP-1 monocytes to endothelial cells. 2019 Dec 2
23 31285419 IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs. 2019 Jul 8 1
24 31780862 Changes in Serum Cytokines May Predict Therapeutic Efficacy of Tofacitinib in Rheumatoid Arthritis. 2019 1
25 29205406 Systematic review with network meta-analysis: first- and second-line pharmacotherapy for moderate-severe ulcerative colitis. 2018 Jan 1
26 29352846 The Janus kinase inhibitor tofacitinib inhibits TNF-α-induced gliostatin expression in rheumatoid fibroblast-like synoviocytes. 2018 Jul-Aug 2
27 29897007 An Economic Evaluation of Tofacitinib Treatment in Rheumatoid Arthritis After Methotrexate or After 1 or 2 TNF Inhibitors from a U.S. Payer Perspective. 2018 Oct 1
28 30174394 Tofacitinib for induction of remission in ulcerative colitis: systematic review and meta-analysis. 2018 Sep-Oct 1
29 28164724 JAK inhibition in inflammatory bowel disease. 2017 Jul 2
30 28570653 Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma. 2017 1
31 28754958 A study on the risk of fungal infection with tofacitinib (CP-690550), a novel oral agent for rheumatoid arthritis. 2017 Jul 28 1
32 29045207 Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors. 2017 Oct 19 4
33 29268845 [Inhibitory effect and mechanism of tofacitinib on the secretion of cytokines by T cells in human peripheral blood]. 2017 Nov 3
34 26932398 Current concepts in the management of rheumatoid arthritis. 2016 Mar 2
35 27579831 An Economic Evaluation of Tofacitinib Treatment in Rheumatoid Arthritis: Modeling the Cost of Treatment Strategies in the United States. 2016 Sep 2
36 27663846 Tofacitinib for the treatment of tumor necrosis factor-α inhibitor refractory esophageal Crohn's disease: a case report. 2016 Sep 23 2
37 27855242 Biologic or tofacitinib monotherapy for rheumatoid arthritis in people with traditional disease-modifying anti-rheumatic drug (DMARD) failure: a Cochrane Systematic Review and network meta-analysis (NMA). 2016 Nov 17 1
38 26152731 Recent progress and perspective in JAK inhibitors for rheumatoid arthritis: from bench to bedside. 2015 Sep 1
39 24342887 Effects of topical Janus kinase inhibition on ocular surface inflammation and immunity. 2014 Feb 1
40 24624736 [A new therapeutical option for chronic inflammation in rheumatology: janus kinases inhibitors (JAK)]. 2014 Jan 22 1
41 23212593 JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical. 2013 May 2
42 23570265 A pharmacokinetic and clinical assessment of tofacitinib for the treatment of rheumatoid arthritis. 2013 Jun 1
43 22121136 The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon. 2012 Mar 4