Sirolimus

tumor necrosis factor ; Homo sapiens







61 Article(s)
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Pub. Year
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1 34236783 Rapamycin and Paclitaxel Affect Human Aortic Smooth Muscle Cells-Derived Foam Cells Viability and Proliferation. 2022 May 2 1
2 33272162 Influence of an Early Application of Mammalian Target of Rapamycin Inhibitors Everolimus and Sirolimus on Acute Vascular Inflammatory Responses After Ischemia-Reperfusion Injury. 2021 Jan 1
3 33609687 TNFα enhances trovafloxacin-induced in vitro hepatotoxicity by inhibiting protective autophagy. 2021 May 15 1
4 33653802 Rapamycin enhances BCG-specific γδ T cells during intravesical BCG therapy for non-muscle invasive bladder cancer: a randomized, double-blind study. 2021 Mar 1
5 33957967 Decreased microRNA-155 in Behcet's disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production. 2021 May 6 1
6 34058434 Enhanced autophagy suppresses inflammation-mediated bone loss through ROCK1 signaling in bone marrow mesenchymal stem cells. 2021 Sep 1
7 34164408 HMGB1 Activates Myeloid Dendritic Cells by Up-Regulating mTOR Pathway in Systemic Lupus Erythematosus. 2021 1
8 34478760 Divergent regulation of inflammatory cytokines by mTORC1 in THP-1-derived macrophages and intestinal epithelial Caco-2 cells. 2021 Nov 1 1
9 34536195 Omp31 of Brucella Inhibits NF-κB p65 Signaling Pathway by Inducing Autophagy in BV-2 Microglia. 2021 Dec 1
10 34668283 Impact of immunosuppression on the immune response to SARS-CoV-2 infection: A mechanistic study. 2021 Dec 1
11 31264496 Interruption of Autophagosome Formation in Cardiovascular Disease, an Evidence for Protective Response of Autophagy. 2020 Apr 1
12 32686984 Effects of Rapamycin Combined with Cisplatin on Tumor Necrosis Factor TNF-α in MG-63 Cells. 2020 Jan-Dec 5
13 32766308 Minocycline Induces Autophagy and Inhibits Cell Proliferation in LPS-Stimulated THP-1 Cells. 2020 1
14 32823598 Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors. 2020 Aug 13 1
15 30546074 Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells. 2019 Sep 1
16 30842775 Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling. 2019 1
17 31540687 The mTOR-RUNX1 pathway regulates DC-SIGN expression in renal tubular epithelial cells. 2019 Nov 12 2
18 31852644 [Role of mammalian target of rapamycin activation in menthol-induced expressions of airway inflammation-related factors in human bronchial epithelial cells in vitro]. 2019 Nov 30 1
19 31885770 Adipose-Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena. 2019 1
20 32194539 mTOR Blockade by Rapamycin in Spondyloarthritis: Impact on Inflammation and New Bone Formation in vitro and in vivo. 2019 1
21 29348392 Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells. 2018 Jan 18 1
22 29619032 An Autocrine TNFα-Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro. 2018 1
23 29772587 Anti-inflammatory Effects of Cardamonin in Ovarian Cancer Cells Are Mediated via mTOR Suppression. 2018 Nov 1
24 28214861 SIRT1 Regulates the Inflammatory Response of Vascular Adventitial Fibroblasts through Autophagy and Related Signaling Pathway. 2017 1
25 28432555 Rotundarpene inhibits TNF-α-induced activation of the Akt, mTOR, and NF-κB pathways, and the JNK and p38 associated with production of reactive oxygen species. 2017 Oct 1
26 28765952 mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway. 2017 Sep 1
27 27198515 Brefeldin A reduces tumor necrosis factor-α-stimulated production of inflammatory mediators by suppressing the Akt, mTOR, and NF-κB pathways in human keratinocytes. 2016 Sep 1
28 27221774 Flavonoid myricetin inhibits TNF-α-stimulated production of inflammatory mediators by suppressing the Akt, mTOR and NF-κB pathways in human keratinocytes. 2016 Aug 5 1
29 27350635 Th1, Th2 and Th17 Cytokine Profile in Patients with Multiple Sclerosis Following Treatment with Rapamycin. 2016 Jun 1
30 27871466 Autophagy protects against oxidized low density lipoprotein-mediated inflammation associated with preeclampsia. 2016 Dec 1
31 24882386 Effect of everolimus on the immunomodulation of the human neutrophil inflammatory response and activation. 2015 Jan 1
32 25171343 Rapamycin plays a neuroprotective effect after spinal cord injury via anti-inflammatory effects. 2015 Jan 1
33 25673929 Synergistic Inhibition of Tumor Necrosis Factor-Alpha-Stimulated Pro-Inflammatory Cytokine Expression in HaCaT Cells by a Combination of Rapamycin and Mycophenolic Acid. 2015 Feb 1
34 25770080 Inhibition of mTOR pathway restrains astrocyte proliferation, migration and production of inflammatory mediators after oxygen-glucose deprivation and reoxygenation. 2015 Apr-May 1
35 25942007 mTORC1 Regulates Flagellin-Induced Inflammatory Response in Macrophages. 2015 1
36 26407295 Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System. 2015 1
37 24516119 Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2. 2014 Mar 10 2
38 25150927 Axonal protection by modulation of p62 expression in TNF-induced optic nerve degeneration. 2014 Oct 3 2
39 23308138 Profiling sirolimus-induced inflammatory syndrome: a prospective tricentric observational study. 2013 1
40 22034068 Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection. 2012 Apr 1
41 22132896 Preconditioning donor with a combination of tacrolimus and rapamacyn to decrease ischaemia-reperfusion injury in a rat syngenic kidney transplantation model. 2012 Jan 1
42 22923157 Autophagy modulators sensitize prostate epithelial cancer cell lines to TNF-alpha-dependent apoptosis. 2012 Nov 1
43 24116273 Destabilization of TNF-α mRNA by Rapamycin. 2012 Jan 1
44 19567381 Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents. 2010 Jan 2
45 19879324 p70 S6 kinase limits tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblast-like cells. 2010 Feb 5 1
46 20139176 Inflammatory stimulation and hypoxia cooperatively activate HIF-1{alpha} in bronchial epithelial cells: involvement of PI3K and NF-{kappa}B. 2010 May 1
47 18834941 Different profile of gene expression of cytokines in peripheral blood mononuclear cells of transplant recipients treated with m-TOR inhibitor and calcineurin inhibitor. 2009 Jan 2
48 19131641 Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury. 2009 Aug 1
49 19527683 Autophagy-mediated anti-tumoral activity of imiquimod in Caco-2 cells. 2009 Aug 28 1
50 17971516 TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK. 2008 Feb 1