Tacrolimus

tumor necrosis factor ; Homo sapiens







64 Article(s)
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1 34607938 The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients. 2021 Nov 15 1
2 31838663 Tacrolimus Inhibits TNF-α/IL-17A-Produced pro-Inflammatory Effect on Human Keratinocytes by Regulating IκBζ. 2020 Apr 5
3 32067305 Cytokine profile in children with food allergy following liver transplantation. 2020 Mar 1
4 32180132 Crohn's and Parkinson's Disease-Associated LRRK2 Mutations Alter Type II Interferon Responses in Human CD14+ Blood Monocytes Ex Vivo. 2020 Dec 1
5 32719413 Comparative efficacy of antitumor necrosis factor agents and tacrolimus in naïve steroid-refractory ulcerative colitis patients. 2020 Jul 27 2
6 32736525 FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. 2020 Jul 31 2
7 30124124 Tacrolimus for the treatment of immune-related adverse effects refractory to systemic steroids and anti-tumor necrosis factor α therapy. 2019 Jul 2
8 30983820 Performance of tacrolimus in hospitalized patients with steroid-refractory acute severe ulcerative colitis. 2019 Apr 7 1
9 31087207 Axonal Protection by Tacrolimus with Inhibition of NFATc1 in TNF-Induced Optic Nerve Degeneration. 2019 Jul 5
10 31949424 Concomitant Treatment with Etanercept and Tacrolimus Synergistically Attenuates Arthritis Progression via Inhibition of Matrix Metalloproteinase-3 Production and Osteoclastogenesis in Human TNF-α Transgenic Mice. 2019 1
11 29314738 Long-term efficacy and safety of add-on tacrolimus for persistent, active rheumatoid arthritis despite treatment with methotrexate and tumor necrosis factor inhibitors. 2018 Mar 1
12 29520229 Tacrolimus Reverses UVB Irradiation-Induced Epidermal Langerhans Cell Reduction by Inhibiting TNF-α Secretion in Keratinocytes via Regulation of NF-κB/p65. 2018 5
13 29527316 Outcome of tacrolimus and vedolizumab after corticosteroid and anti-TNF failure in paediatric severe colitis. 2018 2
14 27181115 The efficacy and safety of additional administration of tacrolimus in patients with rheumatoid arthritis who showed an inadequate response to tocilizumab. 2017 Jan 1
15 28060893 Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis. 2017 3
16 25315214 Tacrolimus suppresses atopic dermatitis-associated cytokines and chemokines in monocytes. 2016 Jun 3
17 24707135 Clinical management of inflammatory bowel disease in the organ recipient. 2014 Apr 7 1
18 24951257 A global consensus on the classification, diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease. 2014 Sep 1
19 25531359 Role of immunosuppressives in special situations: perianal disease and postoperative period. 2014 1
20 22404745 Endothelin-1 enhances the proliferation of normal human melanocytes in a paradoxical manner from the TNF-α-inhibited condition, but tacrolimus promotes exclusively the cellular migration without proliferation: a proposed action mechanism for combination therapy of phototherapy and topical tacrolimus in vitiligo treatment. 2013 May 1
21 23518805 Tacrolimus salvage in anti-tumor necrosis factor antibody treatment-refractory Crohn's disease. 2013 May 3
22 22132896 Preconditioning donor with a combination of tacrolimus and rapamacyn to decrease ischaemia-reperfusion injury in a rat syngenic kidney transplantation model. 2012 Jan 1
23 22576566 [Treatment strategy for refractory inflammatory bowel disease to improve endoscopic lesions and long-term prognosis]. 2012 1
24 22579702 Tacrolimus potently inhibits human osteoclastogenesis induced by IL-17 from human monocytes alone and suppresses human Th17 differentiation. 2012 Aug 2
25 22885734 Tacrolimus down-regulates chemokine expressions on rheumatoid synovial fibroblasts: screening by a DNA microarray. 2012 Dec 1
26 22895606 Tacrolimus (FK506) suppresses TNF-α-induced CCL2 (MCP-1) and CXCL10 (IP-10) expression via the inhibition of p38 MAP kinase activation in human colonic myofibroblasts. 2012 Nov 4
27 20238216 FK506 inhibition of gliostatin/thymidine phosphorylase production induced by tumor necrosis factor-α in rheumatoid fibroblast-like synoviocytes. 2011 Jul 2
28 21172435 Surfactant protein A (SP-A)-tacrolimus complexes have a greater anti-inflammatory effect than either SP-A or tacrolimus alone on human macrophage-like U937 cells. 2011 Apr 1
29 21434949 Tacrolimus suppresses IL-12/IL23 p40 in Crohn's disease and heals fistulae refractory to anti-TNF-α therapy. 2011 Apr 1
30 19880819 Mechanisms behind local immunosuppression using inhaled tacrolimus in preclinical models of lung transplantation. 2010 Oct 1
31 20159692 [Effect of FK506 on cytokine secretion in whole blood]. 2010 Feb 2
32 18957484 Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the JAK/STAT pathway. 2009 Oct 1
33 19153737 Adding low dose tacrolimus in rheumatoid arthritis patients with an inadequate response to tumor necrosis factor inhibitor therapies. 2009 Sep 1
34 18262659 Clinical efficacy and cytokine network-modulating effects of tacrolimus in myasthenia gravis. 2008 Mar 1
35 17568575 Polymorphisms of tumor necrosis factor-alpha, interleukin-10, cytochrome P450 3A5 and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus. 2007 Aug 1
36 17880416 Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells. 2007 Oct 2
37 16303143 Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells. 2006 Apr 18 3
38 16930148 Tacrolimus treatment of plasmacytoid dendritic cells inhibits dinucleotide (CpG-)-induced tumour necrosis factor-alpha secretion. 2006 Dec 1
39 16985094 Novel therapies for Crohn's disease: focus on immunomodulators and antibiotics. 2006 Oct 1
40 17149058 Behçet disease: recommendation for clinical management of mucocutaneous lesions. 2006 Dec 1
41 15598440 FK506 suppresses E-selectin, ICAM-1 and VCAM-1 expression on vascular endothelial cells by inhibiting tumor necrosis factor alpha secretion from peripheral blood mononuclear cells. 2005 Jan 21 2
42 15851377 FK506 enhances triptolide-induced down-regulation of cyclooxygenase-2, inducible nitric oxide synthase as well as their products PGE2 and NO in TNF-alpha-stimulated synovial fibroblasts from rheumatoid arthritic patients. 2005 Mar 29 3
43 16181452 FK506 inhibits tumour necrosis factor-alpha secretion in human keratinocytes via regulation of nuclear factor-kappaB. 2005 Oct 3
44 15243524 Topical tacrolimus therapy for vitiligo: therapeutic responses and skin messenger RNA expression of proinflammatory cytokines. 2004 Jul 1
45 15377358 FK506 independently upregulates transforming growth factor beta and downregulates inducible nitric oxide synthase in cultured human keratinocytes: possible mechanisms of how tacrolimus ointment interacts with atopic skin. 2004 Sep 1
46 12621554 [Enhancement by FK506 of triptolide-induced inhibition of expression of COX-2 and iNOS in human rheumatoid arthritis synovial fibroblasts]. 2003 Mar 1
47 11169223 Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production. 2001 Feb 1
48 11428741 Tacrolimus inhibits cytokine production and chemical mediator release following antigen stimulation of passively sensitized human lung tissues. 2001 Jun 2
49 11523700 Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells. 2001 Sep 1
50 10928971 FK506 potently inhibits T cell activation induced TNF-alpha and IL-1beta production in vitro by human peripheral blood mononuclear cells. 2000 Aug 4