| 1 |
35311151 | Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming. | 2022 |
2 |
| 2 |
34579716 | Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker. | 2021 Sep 27 |
2 |
| 3 |
32189555 | The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs. | 2020 |
3 |
| 4 |
33292474 | Thymidine kinase 1 through the ages: a comprehensive review. | 2020 Nov 27 |
1 |
| 5 |
30612642 | Monitoring of successive phosphorylations of thymidine using free and immobilized human nucleoside/nucleotide kinases by Flow Injection Analysis with High-Resolution Mass Spectrometry. | 2019 Feb 21 |
2 |
| 6 |
31383553 | Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency. | 2019 Aug |
1 |
| 7 |
27655645 | Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging. | 2017 Apr 11 |
2 |
| 8 |
26778585 | 18F-FLT PET imaging of cellular proliferation in pancreatic cancer. | 2016 Mar |
1 |
| 9 |
25881156 | Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways. | 2015 Mar 21 |
3 |
| 10 |
24285724 | Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging. | 2014 Feb 1 |
1 |
| 11 |
25152750 | FISH comets show that the salvage enzyme TK1 contributes to gene-specific DNA repair. | 2014 |
1 |
| 12 |
23318906 | Synthesis of N3-substituted carboranyl thymidine bioconjugates and their evaluation as substrates of recombinant human thymidine kinase 1. | 2013 Feb |
1 |
| 13 |
24124690 | Phosphorylation of nucleoside-metallacarborane and carborane conjugates by nucleoside kinases. | 2013 |
1 |
| 14 |
22175713 | Synthesis, biological evaluation, and radioiodination of halogenated closo-carboranylthymidine analogues. | 2012 Jan 2 |
1 |
| 15 |
22385435 | Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1. | 2012 May |
1 |
| 16 |
22442154 | Trypanosoma brucei thymidine kinase is tandem protein consisting of two homologous parts, which together enable efficient substrate binding. | 2012 May 18 |
1 |
| 17 |
22462611 | Deoxyribonucleoside kinases in two aquatic bacteria with high specificity for thymidine and deoxyadenosine. | 2012 Jun |
1 |
| 18 |
21673071 | Combining small interfering RNAs targeting thymidylate synthase and thymidine kinase 1 or 2 sensitizes human tumor cells to 5-fluorodeoxyuridine and pemetrexed. | 2011 Sep |
1 |
| 19 |
21737633 | Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake. | 2011 Jun |
2 |
| 20 |
20156163 | Pyrimidine nucleosides in molecular PET imaging of tumor proliferation. | 2010 |
2 |
| 21 |
20231284 | Prodrug activation by Cryptosporidium thymidine kinase. | 2010 May 21 |
1 |
| 22 |
20359195 | Charge dependent substrate activity of C3' and N3 functionalized, organometallic technetium and rhenium-labeled thymidine derivatives toward human thymidine kinase 1. | 2010 Apr 21 |
4 |
| 23 |
20544518 | Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage. | 2010 Jun |
2 |
| 24 |
20544519 | Thymidine kinase 1 is a potential marker for prognosis and monitoring the response to treatment of patients with breast, lung, and esophageal cancer and non-Hodgkin's lymphoma. | 2010 Jun |
2 |
| 25 |
20544521 | Enzymatic regulation of cytosolic thymidine kinase 1 and mitochondrial thymidine kinase 2: a mini review. | 2010 Jun |
1 |
| 26 |
19087190 | Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration. | 2009 Jan |
1 |
| 27 |
19159229 | Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. | 2009 Feb 17 |
1 |
| 28 |
19400575 | Organometallic [Re(CO)3]+ and [Re(CO)2(NO)]2+ labeled substrates for human thymidine kinase 1. | 2009 Jun 15 |
1 |
| 29 |
19654105 | Thymidine kinase 1 and thymidine phosphorylase expression in non-small-cell lung carcinoma in relation to angiogenesis and proliferation. | 2009 Nov |
3 |
| 30 |
20560637 | Nonpolar nucleoside mimics as active substrates for human thymidine kinases. | 2009 Apr 22 |
2 |
| 31 |
18295188 | Effect of AZT on thymidine phosphorylation in cultured H9c2, U-937, and Raji cell lines. | 2008 Apr 15 |
1 |
| 32 |
18455811 | Substrate specificity of feline and canine herpesvirus thymidine kinase. | 2008 Aug |
3 |
| 33 |
18782048 | Synthesis of N3-substituted thymidine analogues for measurement of cellular kinase activity. | 2008 Sep |
3 |
| 34 |
17227951 | Hiding human thymidine kinase 1 from APC/C-mediated destruction by thymidine binding. | 2007 Apr |
8 |
| 35 |
17407781 | Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. | 2007 May 25 |
1 |
| 36 |
17448496 | Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases. | 2007 Jun 8 |
1 |
| 37 |
17525869 | Mitotic control of dTTP pool: a necessity or coincidence? | 2007 Jul |
1 |
| 38 |
16473525 | High-level expression and purification of human thymidine kinase 1: quaternary structure, stability, and kinetics. | 2006 Jun |
1 |
| 39 |
16631084 | Synthesis and evaluation of a radiometal-labeled macrocyclic chelator-derivatised thymidine analog. | 2006 Apr |
2 |
| 40 |
16831554 | Hydrophilically enhanced 3-carboranyl thymidine analogues (3CTAs) for boron neutron capture therapy (BNCT) of cancer. | 2006 Oct 15 |
3 |
| 41 |
17065083 | Purification and characterization of wild-type and mutant TK1 type kinases from Caenorhabditis elegans. | 2006 |
2 |
| 42 |
17065087 | Effect of C-terminal of human cytosolic thymidine kinase (TK1) on in vitro stability and enzymatic properties. | 2006 |
1 |
| 43 |
14697231 | Perturbation of ATP-induced tetramerization of human cytosolic thymidine kinase by substitution of serine-13 with aspartic acid at the mitotic phosphorylation site. | 2004 Jan 16 |
1 |
| 44 |
15308203 | The synthesis and biochemical evaluation of thymidine analogues substituted with nido carborane at the N-3 position. | 2004 Nov |
2 |
| 45 |
15336255 | Synthesis of ethyleneoxide modified 3-carboranyl thymidine analogues and evaluation of their biochemical, physicochemical, and structural properties. | 2004 Sep 15 |
1 |
| 46 |
15342416 | Evaluation of human thymidine kinase 1 substrates as new candidates for boron neutron capture therapy. | 2004 Sep 1 |
3 |
| 47 |
15628745 | Phosphorylation of isocarbostyril- and difluorophenyl-nucleoside thymidine mimics by the human deoxynucleoside kinases. | 2004 |
1 |
| 48 |
12502817 | Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression. | 2003 Jan |
1 |
| 49 |
12123744 | 3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells. | 2002 Jul 15 |
1 |
| 50 |
11563094 | Synthesis and biological evaluation of boronated nucleosides for boron neutron capture therapy (BNCT) of cancer. | 2001 Apr-Jul |
1 |