Pyruvic Acid

pyruvate dehydrogenase E1 subunit alpha 1 ; Homo sapiens







11 Article(s)
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1 34488935 Drug evaluation based on phosphomimetic PDHA1 reveals the complexity of activity-related cell death in A549 non-small cell lung cancer cells. 2021 Nov 1
2 32641713 Oxidized ATM promotes breast cancer stem cell enrichment through energy metabolism reprogram-mediated acetyl-CoA accumulation. 2020 Jul 3 2
3 33336150 AMPK maintains TCA cycle through sequential phosphorylation of PDHA to promote tumor metastasis. 2020 Nov 25 2
4 31100640 Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis. 2019 Jul 1
5 25104357 Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect. 2014 Sep 19 2
6 25152236 SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. 2014 Nov 2
7 10913026 Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. 2000 Aug 2
8 10070014 Pyruvate dehydrogenase activation in inactive muscle during and after maximal exercise in men. 1999 Mar 1
9 10409125 PDH activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humans. 1999 Jul 1
10 7573423 Skeletal muscle pyruvate dehydrogenase activity during maximal exercise in humans. 1995 Sep 1
11 3785292 Improved purification of the pyruvate dehydrogenase complex from Ascaris suum body wall muscle and characterization of PDHa kinase activity. 1986 Nov 1