Tetradecanoylphorbol Acetate

jun proto-oncogene ; Mus musculus







135 Article(s)
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51 12032821 Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model. 2002 May 30 2
52 12058867 1Alpha25(OH)2D3 interferes with retinoic acid-induced inhibition of c-fos gene expression for AP-1 formation in osteoblastic cells. 2002 Mar 1
53 12101411 Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathway. 2002 Jul 18 1
54 12112313 Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-jun. 2002 Jun 2
55 12115530 Inhibitory effects of the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol ester-induced ornithine decarboxylase activity, papilloma formation, cyclooxygenase-2 expression, inducible nitric oxide synthase expression and nuclear transcription factor kappa B activation in mouse skin. 2002 Aug 1 1
56 12204819 AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. 2002 Sep 2
57 12209884 Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process. 2002 Oct 5
58 11231886 Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin. 2001 2
59 11285196 Dietary energy restriction inhibits ERK but not JNK or p38 activity in the epidermis of SENCAR mice. 2001 Apr 4
60 11358830 Organ-specific activation of activator protein-1 in transgenic mice by 12-o-tetradecanoylphorbol-13-acetate with different administration methods. 2001 May 15 20
61 11507057 Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model. 2001 Aug 15 2
62 11532864 Inhibition of phorbol ester-induced AP-1-DNA binding, c-Jun protein and c-jun mRNA by dietary energy restriction is reversed by adrenalectomy in SENCAR mouse epidermis. 2001 Sep 8
63 10662601 Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol). 2000 Feb 15 2
64 10737590 Regulation of mouse delta-opioid receptor gene transcription: involvement of the transcription factors AP-1 and AP-2. 2000 Apr 1
65 10754199 Momordin I, a compound of ampelopsis radix, inhibits AP-1 activation induced by phorbol ester. 2000 Apr 28 2
66 10842315 Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells. 2000 May 1
67 11216470 Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1. 2000 1
68 9873060 Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced activator protein 1 activation. 1999 Jan 8 2
69 9886845 Transcriptional interferences between normal or mutant androgen receptors and the activator protein 1--dissection of the androgen receptor functional domains. 1999 Jan 1
70 9891065 Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element. 1999 Feb 1
71 10064335 Glucocorticoid mediation of dietary energy restriction inhibition of mouse skin carcinogenesis. 1999 Feb 4
72 10200990 Estradiol suppresses type I collagen synthesis in mesangial cells via activation of activator protein-1. 1999 Apr 1
73 10370867 Cancer chemopreventive activity of resveratrol. 1999 1
74 10449779 Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. 1999 Aug 17 9
75 10523861 Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation. 1999 Oct 14 2
76 10535756 Inhibition of 12-O-tetradecanoylphorbol-13-acetate induction of c-fos mRNA by the protein kinase A inhibitor N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide. 1999 Nov 15 2
77 10563991 Inhibition of TPA-induced protein kinase C and transcription activator protein-1 binding activities by theaflavin-3,3'-digallate from black tea in NIH3T3 cells. 1999 Apr 3
78 9703914 PKC-dependent modulation of IkB alpha-NFkB pathway in low metastatic B16F1 murine melanoma cells and in highly metastatic BL6 cells. 1998 Jul-Aug 2
79 10381133 Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin. 1998 Dec 11 1
80 9022811 Activation of AP-1 by okadaic acid in mouse keratinocytes associated with hyperphosphorylation of c-jun. 1997 Jan 4
81 9159159 Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. 1997 May 27 3
82 9254887 A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes. 1997 Jul 5
83 9270030 Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. 1997 Aug 15 1
84 9290125 Inhibitory effects of phytopolyphenols on TPA-induced transformation, PKC activation, and c-jun expression in mouse fibroblast cells. 1997 2
85 9315102 Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters. 1997 Sep 4
86 9591190 Inhibitory effects of curcumin on tumorigenesis in mice. 1997 2
87 8622882 Regulation of epidermal growth factor receptor by activated H-ras and V-myc oncogenes in mouse Balb/3T3 cells: possible roles of AP-1. 1996 Apr 18 1
88 8625496 Involvement of glutathione in induction of c-jun proto-oncogene by methylmethanesulfonate in NIH 3T3 cells. 1996 Apr 1
89 8649769 Okadaic acid stimulated TRE binding activity in a papilloma producing mouse keratinocyte cell line involves increased AP-1 expression. 1996 Jun 6 1
90 8695223 Inhibitions of protein kinase C and proto-oncogene expressions in NIH 3T3 cells by apigenin. 1996 Jan 2
91 8969886 Regulation of growth by ACTH in the Y-1 line of mouse adrenocortical cells. 1996 Nov 1
92 8989917 Inhibition of protein kinase C and proto-oncogene expression by crocetin in NIH/3T3 cells. 1996 Dec 1
93 21594328 Inhibitory effect of genistein on a tumor promoter-induced c-fos and c-jun expression in mouse skin. 1996 Jan 4
94 7553596 A labile hyperphosphorylated c-Fos protein is induced in mouse fibroblast cells treated with a combination of phorbol ester and anti-tumor promoter curcumin. 1995 Sep 4 1
95 7579389 Arachidonic acid induces c-jun gene expression in stromal cells stimulated by interleukin-1 and tumor necrosis factor-alpha: evidence for a tyrosine-kinase-dependent process. 1995 Oct 15 2
96 7602115 TGF-beta induces expression of monocyte chemoattractant JE/monocyte chemoattractant protein 1 via transcriptional factor AP-1 induced by protein kinase in osteoblastic cells. 1995 Jul 1 1
97 7766308 c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation. 1995 May 6
98 7818761 Expression of epidermal ornithine decarboxylase and nuclear proto-oncogenes in phorbol ester tumor promotion-sensitive and -resistant mice. 1995 Jan 2
99 7829270 Tumor-promoting activity of 2,4-dinitrofluorobenzene. 1995 Feb 8 1
100 7835696 An ATF/CREB-binding site is essential for cell-specific and inducible transcription of the murine MIP-1 beta cytokine gene. 1995 Jan 23 1