Tetradecanoylphorbol Acetate

jun proto-oncogene ; Mus musculus







135 Article(s)
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1 34724217 Biphasic effect of mechanical stress on lymphocyte activation. 2022 Feb 1
2 34645824 Phorbol-12-myristate 13-acetate inhibits Nephronectin gene expression via Protein kinase C alpha and c-Jun/c-Fos transcription factors. 2021 Oct 13 1
3 33144667 A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2. 2020 Nov 3 2
4 26100520 Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate. 2015 Sep 2
5 23852815 The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice. 2014 Jun 1
6 24380573 Naturally occurring phenolic acids modulate TPA-induced activation of EGFR, AP-1, and STATs in mouse epidermis. 2014 2
7 25374129 Piceatannol inhibits phorbol ester-induced expression of COX-2 and iNOS in HR-1 hairless mouse skin by blocking the activation of NF-κB and AP-1. 2014 Dec 2
8 23002036 Resistin knockout mice exhibit impaired adipocyte glucose-dependent insulinotropic polypeptide receptor (GIPR) expression. 2013 Feb 2
9 23429041 Inhibitory effect of dihydroartemisinin against phorbol ester-induced cyclooxygenase-2 expression in macrophages. 2013 Jun 1
10 23708096 Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. 2013 May 24 2
11 23835587 Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice. 2013 Sep 1
12 22542552 Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages. 2012 Jul 2
13 22842666 Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis. 2012 Nov 2
14 23105093 Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1. 2012 Dec 14 1
15 21400615 5'-Nitro-indirubinoxime inhibits epidermal growth factor- and phorbol ester-induced AP-1 activity and cell transformation through inhibition of phosphorylation of Pin1. 2011 Dec 6
16 21480506 Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice. 2011 Apr 2
17 21542454 Azadirachta indica exerts chemopreventive action against murine skin cancer: studies on histopathological, ultrastructural changes and modulation of NF-kappaB, AP-1, and STAT1. 2011 1
18 22001392 AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. 2011 Dec 1 2
19 22210038 Inhibitory effect of Lactobacillus plantarum K-1 on passive cutaneous anaphylaxis reaction and scratching behavior in mice. 2011 Dec 1
20 20179211 Diallyl trisulfide inhibits phorbol ester-induced tumor promotion, activation of AP-1, and expression of COX-2 in mouse skin by blocking JNK and Akt signaling. 2010 Mar 1 7
21 20232358 Dietary energy restriction, in part through glucocorticoid hormones, mediates the impact of 12-O-tetradecanoylphorbol-13-acetate on jun D and fra-1 in Sencar mouse epidermis. 2010 Jun 5
22 20469933 Protein kinase C epsilon regulation of translocator protein (18 kDa) Tspo gene expression is mediated through a MAPK pathway targeting STAT3 and c-Jun transcription factors. 2010 Jun 15 1
23 18234971 A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression. 2008 Jan 1
24 18400024 Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation. 2008 Jun 1
25 18425423 Chemopreventive activity of lantadenes on two-stage carcinogenesis model in Swiss albino mice: AP-1 (c-jun), NFkappaB (p65) and P53 expression by ELISA and immunohistochemical localization. 2008 Jul 1
26 19139002 Delphinidin attenuates neoplastic transformation in JB6 Cl41 mouse epidermal cells by blocking Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling. 2008 Dec 1
27 17143503 Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate. 2007 Jan 1
28 17234724 Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide. 2007 Jul 1
29 17372274 Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets. 2007 Jul 4
30 17440073 SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation. 2007 Apr 15 7
31 17846172 SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. 2007 Sep 10 1
32 16365389 Cutting edge: the AP-1 subunit JunB determines NK cell-mediated target cell killing by regulation of the NKG2D-ligand RAE-1epsilon. 2006 Jan 1 1
33 16478713 Affinity selection of DNA-binding protein complexes using mRNA display. 2006 Feb 14 1
34 16740738 Involvement of the paxillin pathway in JB6 Cl41 cell transformation. 2006 Jun 1 1
35 16910781 ROS-production-mediated activation of AP-1 but not NFkappaB inhibits glutamate-induced HT4 neuronal cell death. 2006 Jul-Aug 2
36 16999939 Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets. 2006 Nov 30 3
37 15639337 Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets. 2005 Jan 31 4
38 15826073 Antioxidant activity in lingonberries (Vaccinium vitis-idaea L.) and its inhibitory effect on activator protein-1, nuclear factor-kappaB, and mitogen-activated protein kinases activation. 2005 Apr 20 4
39 15972968 c-Fos-dependent induction of the small ras-related GTPase Rab11a in skin carcinogenesis. 2005 Jul 2
40 16277019 Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds. 2005 Nov-Dec 2
41 14661063 Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development. 2004 Mar 11 1
42 14729583 Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin. 2004 May 6
43 15063796 Tumor promoter-induced MMP-13 gene expression in a model of initiated epidermis. 2004 Apr 30 2
44 15064752 Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation. 2004 May 27 1
45 15520189 Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis. 2004 Nov 1 1
46 15630167 Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets. 2004 2
47 12433932 NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2. 2003 Jan 24 2
48 12527890 Differential requirement of EGF receptor and its tyrosine kinase for AP-1 transactivation induced by EGF and TPA. 2003 Jan 16 10
49 12616721 Detection of the content and activity of the transcription factor AP-1 in a multistage skin carcinogenesis model. 2003 2
50 12632075 Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway. 2003 Apr 1