zileuton

arachidonate 5-lipoxygenase ; Rattus norvegicus







41 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30730768 Involvement of leukotriene pathway in the development of sevoflurane-induced pica in rats. 2019 May 1
2 31796842 Participation of 5-lipoxygenase and LTB4 in liver regeneration after partial hepatectomy. 2019 Dec 3 1
3 28860177 Effect of zileuton on osteoporotic bone and its healing, expression of bone, and brain genes in rats. 2018 Jan 1 2
4 29355720 Zileuton alleviates acute cisplatin nephrotoxicity: Inhibition of lipoxygenase pathway favorably modulates the renal oxidative/inflammatory/caspase-3 axis. 2018 Mar 1
5 29681851 DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention. 2018 1
6 27849187 Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. 2017 Apr 1
7 29299197 Inhibition of 5-lipoxygenase inhibitor zileuton in high-fat diet-induced nonalcoholic fatty liver disease progression model. 2017 Nov 1
8 27058978 Investigations on the role of leukotrienes in remote hind limb preconditioning-induced cardioprotection in rats. 2016 May 1 1
9 27380038 5-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway. 2016 Oct 1
10 26495739 [ROLE OF THROMBOXANE AND LEUKOTRIENES IN MECHANISMS OF CONTRACTILE REACTIONS OF PORTAL VEIN, INDUCED BY ACETYLCHLINE AND PHENYLEPHRINE]. 2015 1
11 24858057 Regulation of rotenone-induced microglial activation by 5-lipoxygenase and cysteinyl leukotriene receptor 1. 2014 Jul 14 2
12 24998649 [Zileuton, a 5-lipoxygenase inhibitor, attenuates mouse microglial cell-mediated rotenone toxicity in PC12 cells]. 2014 May 3
13 23505109 [Expression of 5-lipoxygenase in hippocampal CA1 neuronal damage following global cerebral ischemia in rats]. 2013 Jan 2
14 23695166 5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia. 2013 Dec 5
15 22734808 Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1. 2012 Jun 26 1
16 19781629 The cardioprotective effects of zileuton, a 5-lipoxygenase inhibitor, are mediated by COX-2 via activation of PKC delta. 2010 Jan 2
17 20139896 Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells. 2010 Feb 3
18 20204486 Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats. 2010 Oct 1
19 19309543 5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9. 2009 Oct 4
20 19580807 CJ-13610, an orally active inhibitor of 5-lipoxygenase is efficacious in preclinical models of pain. 2009 Sep 1 2
21 18295198 A rat air pouch model for evaluating the efficacy and selectivity of 5-lipoxygenase inhibitors. 2008 Apr 14 3
22 18452962 Crotoxin alters lymphocyte distribution in rats: Involvement of adhesion molecules and lipoxygenase-derived mediators. 2008 Jun 15 1
23 16373074 Lipoxygenase-derived eicosanoids are involved in the inhibitory effect of Crotalus durissus terrificus venom or crotoxin on rat macrophage phagocytosis. 2006 Mar 1
24 16714363 Activated neutrophil-mediated sickle red blood cell adhesion to lung vascular endothelium: role of phosphatidylserine-exposed sickle red blood cells. 2006 Oct 2
25 16737726 Crotoxin induces actin reorganization and inhibits tyrosine phosphorylation and activity of small GTPases in rat macrophages. 2006 Jun 15 1
26 15265319 Effect of zileuton in radicular pain induced by herniated nucleus pulposus in rats. 2004 1
27 15326064 Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone. 2004 Sep 7 1
28 15339030 Effect of 5-lipoxygenase inhibition on events associated with inflammatory bowel disease in rats. 2004 Jul 1
29 11748055 Activated polymorphonuclear cells increase sickle red blood cell retention in lung: role of phospholipids. 2002 Jan 1
30 11430933 In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. 2001 Jun 22 2
31 10694244 Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells. 2000 Jan 1
32 9784515 5-Lipoxygenase reaction products modulate alveolar macrophage phagocytosis of Klebsiella pneumoniae. 1998 Nov 1
33 8796377 The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats. 1996 Jun 2
34 8984030 Intracolonic administration of zileuton, a selective 5-lipoxygenase inhibitor, accelerates healing in a rat model of chronic colitis. 1996 Jun 2
35 7922131 Novel bishydroxamic acids as 5-lipoxygenase inhibitors. 1994 Mar 1
36 7905704 Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats. 1993 Jul 2
37 8273581 Effect of 5-lipoxygenase inhibitors on in situ LTB4 biosynthesis following calcium ionophore stimulation in the rat pleural cavity. 1993 1
38 8394967 Evaluation of 5-lipoxygenase inhibitors, zileuton, A-78773 and ICI-D-2138 in an ionophore (A-23187)-induced pleural inflammation model in the rat. 1993 1
39 1650523 Tumour necrosis factor production in a rat airpouch model of inflammation: role of eicosanoids. 1991 Mar 1
40 1817962 Inhibition of leukotriene biosynthesis in the rat peritoneal cavity. 1991 Dec 3 1
41 1848634 5-lipoxygenase inhibitory activity of zileuton. 1991 Mar 1