Simvastatin

transforming growth factor beta 1 ; Homo sapiens







26 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35599097 Corrigendum to "Simvastatin attenuates macrophage-mediated gemcitabine resistance of pancreatic ductal adenocarcinoma by regulating the TGF-β1/Gfi-1" [Canc. Lett. 385 (2017) 65-74]. 2022 Aug 1 1
2 30536599 Simvastatin and the Rho-kinase inhibitor Y-27632 prevent myofibroblast transformation in Peyronie's disease-derived fibroblasts via inhibition of YAP/TAZ nuclear translocation. 2019 Apr 2
3 31934265 Simvastatin Mitigates Apoptosis and Transforming Growth Factor-Beta Upregulation in Stretch-Induced Endothelial Cells. 2019 2
4 30220377 Simvastatin reduces TGF-β1-induced SMAD2/3-dependent human ventricular fibroblasts differentiation: Role of protein phosphatase activation. 2018 Nov 1 6
5 27840243 Simvastatin attenuates macrophage-mediated gemcitabine resistance of pancreatic ductal adenocarcinoma by regulating the TGF-β1/Gfi-1 axis. 2017 Jan 28 4
6 26574150 Statin pretreatment inhibits the lipopolysaccharide-induced epithelial-mesenchymal transition via the downregulation of toll-like receptor 4 and nuclear factor-κB in human biliary epithelial cells. 2016 Jun 3
7 27123120 Simvastatin blocks TGF-β1-induced epithelial-mesenchymal transition in human prostate cancer cells. 2016 May 5
8 30024693 [Different effects of simvastatin on keloid fibroblasts under hypoxia and TGF-β1 treatment]. 2016 Mar 2
9 26559850 Simvastatin ameliorates experimental autoimmune encephalomyelitis by inhibiting Th1/Th17 response and cellular infiltration. 2015 Dec 1
10 24471776 Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts. 2014 Jan-Feb 4
11 24506800 Low intravitreal angiopoietin-2 and VEGF levels in vitrectomized diabetic patients with simvastatin treatment. 2014 Nov 1
12 23817018 Simvastatin attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells. 2013 3
13 24098525 Simvastatin ameliorates liver fibrosis via mediating nitric oxide synthase in rats with non-alcoholic steatohepatitis-related liver fibrosis. 2013 1
14 22127053 Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells. 2012 Feb 29 2
15 22331026 Statins induce the accumulation of regulatory T cells in atherosclerotic plaque. 2012 May 9 1
16 22391067 Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. 2012 Jan-Feb 5
17 20463291 The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle. 2011 Mar 2
18 21864337 Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. 2011 Aug 24 4
19 21968503 Modulators of induction of plasminogen activator inhibitor type-1 in HepG2 cells by transforming growth factor-β. 2011 Nov 1
20 19023089 Efficacy of simvastatin treatment of valvular interstitial cells varies with the extracellular environment. 2009 Feb 2
21 19358180 Simvastatin impairs smad-3 phosphorylation and modulates transforming growth factor beta1-mediated activation of intestinal fibroblasts. 2009 May 3
22 18203812 Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients. 2008 Mar 2
23 15677772 Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts. 2005 Apr 1
24 16045013 [Effect of simvastatin on cardiac fibrosis in patients with essential hypertension]. 2005 Jun 1
25 15298857 Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism. 2004 Dec 3
26 10500210 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors up-regulate transforming growth factor-beta signaling in cultured heart cells via inhibition of geranylgeranylation of RhoA GTPase. 1999 Sep 28 2