Losartan

transforming growth factor beta 1 ; Homo sapiens







61 Article(s)
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1 35415233 Losartan as a Steroid-Sparing Adjunct in a Patient With Features of Refractory Camurati-Engelmann Disease. 2022 Mar-Apr 2
2 35446787 Losartan ameliorates TGF-β1-induced CFTR dysfunction and improves correction by cystic fibrosis modulator therapies. 2022 Jun 1 2
3 33475959 Network Analysis Reveals Proteins Associated with Aortic Dilatation in Mucopolysaccharidoses. 2021 Mar 1
4 33532463 Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion. 2021 Jan 2
5 31613648 Losartan Rescues Inflammation-related Mucociliary Dysfunction in Relevant Models of Cystic Fibrosis. 2020 Feb 1 1
6 30610922 Losartan attenuates progression of osteoarthritis in the synovial temporomandibular and knee joints of a chondrodysplasia mouse model through inhibition of TGF-β1 signaling pathway. 2019 Apr 1
7 31216320 The effects of losartan on cytomegalovirus infection in human trabecular meshwork cells. 2019 5
8 31385893 Angiotensin II Type I Receptor Blockade Is Associated with Decreased Cutaneous Scar Formation in a Rat Model. 2019 Nov 1
9 30595567 Downregulation of Profibrotic Gene Expression by Angiotensin Receptor Blockers. 2018 Nov 5
10 28849131 Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development. 2017 Nov 1
11 28033321 Atorvastatin, Losartan and Captopril Lead to Upregulation of TGF-β, and Downregulation of IL-6 in Coronary Artery Disease and Hypertension. 2016 2
12 25342281 The revised role of TGF-β in aortic aneurysms in Marfan syndrome. 2015 Feb 10
13 25655494 Profibrosing effect of angiotensin converting enzyme inhibitors in human lung fibroblasts. 2015 Apr 3
14 24398790 SMAD4 mutations causing Myhre syndrome result in disorganization of extracellular matrix improved by losartan. 2014 Aug 1
15 24632204 Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK. 2014 Apr 18 2
16 24659129 Losartan prevents acquired epilepsy via TGF-β signaling suppression. 2014 Jun 3
17 24931486 Pathophysiology and Japanese clinical characteristics in Marfan syndrome. 2014 Aug 1
18 25099136 Positive effects of an angiotensin II type 1 receptor antagonist in Camurati-Engelmann disease: a single case observation. 2014 Oct 2
19 23532685 Angiotensin II Receptor Antagonism Reduces Transforming Growth Factor Beta and Smad Signaling in Thoracic Aortic Aneurysm. 2013 Spring 2
20 24084631 Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels. 2013 1
21 21535912 Losartan enhances the success of myoblast transplantation. 2012 2
22 22372177 Camurati-Engelmann disease--a rare cause of bone pain. 2012 Jan 1
23 21974877 Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone. 2011 Oct 6 1
24 20067609 Losartan therapy in adults with Marfan syndrome: study protocol of the multi-center randomized controlled COMPARE trial. 2010 Jan 12 1
25 20135646 Transforming growth factor beta1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro. 2010 Jun 1 1
26 20964113 Marfan syndrome: clinical manifestations, pathophysiology and new outlook on drug therapy. 2010 Jun 1
27 19278811 Urinary TGF-beta1 as an indicator of antiproteinuric response to angiotensin II receptor blocker in proteinuric renal diseases. 2009 Nov 1
28 19304546 [Effects of losartan on left ventricular hypertrophy and plasma transforming growth factor-beta1 in elderly patients with hypertension]. 2009 Mar 1
29 19635970 Circulating transforming growth factor-beta in Marfan syndrome. 2009 Aug 11 1
30 17227571 Renal allograft protection with angiotensin II type 1 receptor antagonists. 2007 Jan 1
31 17301824 Effect of dual blockade of renin-angiotensin system on TGFbeta1 and left ventricular structure and function in hypertensive patients. 2007 Apr 1
32 18044261 A combination of a PPAR-gamma agonist and an angiotensin II receptor blocker attenuates proinflammatory signaling and stimulates expression of Smad7 in human peritoneal mesothelial cells. 2007 Nov 1
33 16401677 Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves. 2006 Jun 2
34 16482098 Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients. 2006 Apr 3
35 16780390 Different effects of simvastatin and losartan on cytokine levels in coronary artery disease. 2006 2
36 17330452 Effects of losartan on urinary secretion of extracellular matrix and their modulators in type 2 diabetes mellitus patients with microalbuminuria. 2006 Dec 2
37 15770925 Angiotensin II mediates high glucose-induced TGF-beta1 and fibronectin upregulation in HPMC through reactive oxygen species. 2005 Jan-Feb 1
38 16221098 TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture. 2005 Oct 3
39 16422249 Effect of losartan on slowing progression of chronic allograft nephropathy. 2005 Dec 2
40 12754187 Angiotensin II and the fibroproliferative response to acute lung injury. 2004 Jan 1
41 15349718 Molecular and clinical response to angiotensin II receptor antagonist in kidney transplant patients with chronic allograft nephropathy. 2004 Oct 2
42 15382153 Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis. 2004 Nov 1
43 15470652 Losartan improves regional left ventricular systolic and diastolic function in patients with hypertension: accurate evaluation using a newly developed color-coded tissue doppler imaging technique. 2004 Oct 2
44 15560676 Inhibition of the effect of high glucose on the expression of Smad in human peritoneal mesothelial cells. 2004 Oct 2
45 12748343 Effect of losartan and amlodipine on proteinuria and transforming growth factor-beta1 in patients with IgA nephropathy. 2003 Jun 2
46 12904684 Effect of angiotensin II receptor blocker on plasma levels of TGF-beta 1 and interstitial fibrosis in hypertensive kidney transplant patients. 2003 Sep-Oct 2
47 12937228 Antiproteinuric efficacy of losartan in comparison with amlodipine in non-diabetic proteinuric renal diseases: a double-blind, randomized clinical trial. 2003 Sep 3
48 14638911 Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system. 2003 Dec 1
49 11877567 Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-beta levels. 2002 Mar 3
50 12032117 Urinary transforming growth factor-beta excretion in patients with hypertension, type 2 diabetes, and elevated albumin excretion rate: effects of angiotensin receptor blockade and sodium restriction. 2002 Jun 3