Phosphatidylcholines

phosphate cytidylyltransferase 1, choline, alpha isoform ; Mus musculus







47 Article(s)
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1 35007755 De novo phosphatidylcholine synthesis in the small intestinal epithelium is required for normal dietary lipid handling and maintenance of the mucosal barrier. 2022 Apr 2
2 31517566 De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy. 2020 Jun 2
3 30007917 Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis. 2018 Sep 4
4 28855256 From masochistic enzymology to mechanistic physiology and disease. 2017 Oct 20 1
5 29035283 mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion. 2017 Nov 1 2
6 27502364 Phosphatidylcholine as a metabolic cue for determining B cell fate and function. 2016 Dec 2
7 26125130 The hepatic circadian clock regulates the choline kinase α gene through the BMAL1-REV-ERBα axis. 2015 1
8 23155050 ras-Induced up-regulation of CTP:phosphocholine cytidylyltransferase α contributes to malignant transformation of intestinal epithelial cells. 2013 Jan 4 2
9 23074967 Impaired phosphatidylcholine biosynthesis does not attenuate liver regeneration after 70% partial hepatectomy in hepatic CTP:phosphocholine cytidylyltransferase-α deficient mice. 2012 Oct 1
10 21736954 Involvement of CTP:phosphocholine cytidylyltransferase-β2 in axonal phosphatidylcholine synthesis and branching of neurons. 2011 Oct 5
11 21745592 Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis. 2011 Dec 1
12 21982710 Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. 2011 Oct 5 3
13 19684306 Functions of membrane binding domain of CTP:phosphocholine cytidylyltransferase in alveolar type II cells. 2010 Jul 3
14 20026284 Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse. 2010 Apr 1
15 20045741 Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro. 2010 Apr 1
16 20096375 Specific interaction between E2F1 and Sp1 regulates the expression of murine CTP:phosphocholine cytidylyltransferase alpha during the S phase. 2010 Apr 1
17 20525991 Phosphatidylcholine biosynthesis during neuronal differentiation and its role in cell fate determination. 2010 Aug 13 1
18 18042552 Hepatic CTP:phosphocholine cytidylyltransferase-alpha is a critical predictor of plasma high density lipoprotein and very low density lipoprotein. 2008 Jan 25 3
19 18423385 Characterization of the murine CTP:phosphocholine cytidylyltransferase beta gene promoter. 2008 May 4
20 17213195 Phospholipid biosynthesis program underlying membrane expansion during B-lymphocyte differentiation. 2007 Mar 9 2
21 17482853 Changes in macrophage morphology in a Gaucher disease model are dependent on CTP:phosphocholine cytidylyltransferase alpha. 2007 Jul-Aug 4
22 17595447 The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion. 2007 Sep 2
23 16466687 c-Jun N-terminal kinase regulates CTP:phosphocholine cytidylyltransferase. 2006 Mar 1 4
24 15798219 Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). 2005 Apr 4
25 16157598 Sp1 is a co-activator with Ets-1, and Net is an important repressor of the transcription of CTP:phosphocholine cytidylyltransferase alpha. 2005 Dec 9 2
26 15024002 A choline-deficient diet in mice inhibits neither the CDP-choline pathway for phosphatidylcholine synthesis in hepatocytes nor apolipoprotein B secretion. 2004 Jun 4 1
27 15139854 Transcriptional repression of the CTP:phosphocholine cytidylyltransferase gene by sphingosine. 2004 Sep 1 1
28 15331603 Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins. 2004 Nov 5 2
29 15498769 Increased phosphatidylcholine production but disrupted glycogen metabolism in fetal type II cells of mice that overexpress CTP:phosphocholine cytidylyltransferase. 2004 Dec 31 5
30 12842190 Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform. 2003 Jul 4 5
31 12857760 Oxidized lipoproteins inhibit surfactant phosphatidylcholine synthesis via calpain-mediated cleavage of CTP:phosphocholine cytidylyltransferase. 2003 Sep 26 1
32 11829742 Lipid deprivation increases surfactant phosphatidylcholine synthesis via a sterol-sensitive regulatory element within the CTP:phosphocholine cytidylyltransferase promoter. 2002 Feb 15 2
33 11919088 Cell cycle regulation of pulmonary phosphatidylcholine synthesis. 2002 Apr 1
34 12034570 Effect of CTP:phosphocholine cytidylyltransferase overexpression on the mouse lung surfactant system. 2002 Jun 2
35 12183451 Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis. 2002 Oct 18 1
36 12223447 Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide. 2002 Nov 1
37 12353276 Biochemical correlates of thiazolidinedione-induced adipocyte differentiation by high-resolution magic angle spinning NMR spectroscopy. 2002 Oct 1
38 11583989 CTP:phosphocholine cytidylyltransferase alpha is a cytosolic protein in pulmonary epithelial cells and tissues. 2001 Dec 28 5
39 10734122 Tumor necrosis factor-alpha inhibits expression of CTP:phosphocholine cytidylyltransferase. 2000 Mar 31 1
40 10944538 Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response. 2000 Nov 10 1
41 10101264 Macrophage-targeted CTP:phosphocholine cytidylyltransferase (1-314) transgenic mice. 1999 Mar 25 2
42 10216289 Transcriptional activation of the murine CTP:phosphocholine cytidylyltransferase gene (Ctpct): combined action of upstream stimulatory and inhibitory cis-acting elements. 1999 Apr 19 1
43 9148929 The structure of the gene for murine CTP:phosphocholine cytidylyltransferase, Ctpct. Relationship of exon structure to functional domains and identification of transcriptional start sites and potential upstream regulatory elements. 1997 May 16 4
44 7706325 Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step. 1995 Mar 31 1
45 8307580 The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16. 1993 Dec 1
46 1653227 Colony-stimulating factor 1 regulates CTP: phosphocholine cytidylyltransferase mRNA levels. 1991 Sep 5 1
47 2833508 Stimulation of the de novo pathway for the biosynthesis of platelet-activating factor (PAF) via cytidylyltransferase activation in cells with minimal endogenous PAF production. 1988 Apr 25 2