Imatinib Mesylate

KIT proto-oncogene, receptor tyrosine kinase ; Homo sapiens







1113 Article(s)
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101 31371779 Cyclin D1 is a mediator of gastrointestinal stromal tumor KIT-independence. 2019 Sep 2
102 31372066 Novel approaches to treating advanced systemic mastocytosis. 2019 1
103 31471313 Phase I Study of Rapid Alternation of Sunitinib and Regorafenib for the Treatment of Tyrosine Kinase Inhibitor Refractory Gastrointestinal Stromal Tumors. 2019 Dec 15 1
104 32053767 Precision medicine in gastrointestinal stromal tumors. 2019 Nov-Dec 1
105 27384439 Two different KIT mutations may lead to different responses to imatinib in metastatic gastrointestinal stromal tumor. 2018 Mar 1
106 28710566 Remarkable effects of imatinib in a family with young onset gastrointestinal stromal tumors and cutaneous hyperpigmentation associated with a germline KIT-Trp557Arg mutation: case report and literature overview. 2018 Apr 3
107 28736245 Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases. 2018 Apr 1
108 29143894 Mechanism of Resistance in Gastrointestinal Stromal Tumors. 2018 1
109 29334307 Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 of c-kit in a patient-derived orthotopic xenograft (PDOX) nude mouse model. 2018 1
110 29423012 CCDC26 knockdown enhances resistance of gastrointestinal stromal tumor cells to imatinib by interacting with c-KIT. 2018 4
111 29439183 The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis. 2018 May 1
112 29494307 Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells. 2018 Jul 1
113 29523662 A Novel PRKAR1B-BRAF Fusion in Gastrointestinal Stromal Tumor Guides Adjuvant Treatment Decision-Making During Pregnancy. 2018 Mar 1
114 29552659 Management of rectal gastrointestinal stromal tumor. 2018 2
115 29600692 The window of opportunities for targeted therapy in BRAFwt/NRASwt/KITwt melanoma: biology and clinical implications of fusion proteins and other mutations. 2018 Jun 1
116 29620139 Antiproliferative effects of imatinib mesylate on ZR‑75‑1 and MDA‑MB‑231 cell lines via PDGFR‑β, PDGF‑BB, c‑Kit and SCF expression. 2018 Jul 5
117 29623544 SOCS1 gene therapy has antitumor effects in imatinib-resistant gastrointestinal stromal tumor cells through FAK/PI3 K signaling. 2018 Nov 1
118 29682621 Surgery for metastatic gastrointestinal stromal tumor: to whom and how to? 2018 1
119 29704617 The role of small molecule Kit protein-tyrosine kinase inhibitors in the treatment of neoplastic disorders. 2018 Jul 2
120 29724653 A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line. 2018 Jul 15 2
121 29764854 Preclinical Antitumor Activity of a Novel Anti-c-KIT Antibody-Drug Conjugate against Mutant and Wild-type c-KIT-Positive Solid Tumors. 2018 Sep 1 2
122 29969914 Postoperative imatinib in patients with intermediate risk gastrointestinal stromal tumor. 2018 Jul 1
123 29998023 Gastrointestinal stromal tumours: advances in surgical and pharmacological management options. 2018 Jun 1
124 30007460 Kit Mutations: New Insights and Diagnostic Value. 2018 Aug 1
125 30069623 Imatinib Mesylate. 2018 1
126 30101284 Translational insights into gastrointestinal stromal tumor and current clinical advances. 2018 Oct 1 1
127 30159192 Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries. 2018 2
128 30224936 Genomic Subtypes of GISTs for Stratifying Patient Response to Sunitinib following Imatinib Resistance: A Pooled Analysis and Systematic Review. 2018 1
129 30253992 Extensive Leptomeningeal Intracranial and Spinal Metastases in a Patient with a Supratentorial Glioblastoma Multiforme, IDH-Wildtype. 2018 Dec 1
130 30268485 Carving out another slice of the pie: Exceptional response to single agent imatinib in an asian female never-smoker with advanced NSCLC with a de-novo PDGFR-α N848 K mutation. 2018 Oct 1
131 30286478 Cell-Free DNA and Neuromediators in Detecting Aggressive Variant Prostate Cancer. 2018 1
132 30298093 (+)-Usnic Acid Inhibits Migration of c-KIT Positive Cells in Human Colorectal Cancer. 2018 1
133 30311036 A phase II study of imatinib mesylate and letrozole in patients with hormone receptor-positive metastatic breast cancer expressing c-kit or PDGFR-β. 2018 Dec 2
134 30396237 Inhibition of MicroRNA-221 and 222 Enhances Hematopoietic Differentiation from Human Pluripotent Stem Cells via c-KIT Upregulation. 2018 Nov 30 1
135 30396570 Imatinib mesylate elicits extracellular signal-related kinase (ERK) activation and enhances the survival of γ-irradiated epithelial cells. 2018 Dec 2 1
136 30488756 Activated tyrosine kinases in gastrointestinal stromal tumor with loss of KIT oncoprotein expression. 2018 2
137 30500954 Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. 2018 Nov 30 2
138 30545989 Pathologic Complete Response in a Large Gastric GIST: Using Molecular Markers to Achieve Maximal Response to Neoadjuvant Imatinib. 2018 Dec 1
139 30567202 Imatinib and liver toxicity. 2018 Dec 7 2
140 27470968 PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors. 2017 Jan 15 1
141 27687311 Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma. 2017 Jan 1 2
142 27965460 Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate. 2017 Jan 17 4
143 27997714 Genomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumors. 2017 Apr 2
144 28074523 Familial gastrointestinal stromal tumors, lentigines, and café-au-lait macules associated with germline c-kit mutation treated with imatinib. 2017 Feb 1
145 28192400 Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors. 2017 Jun 29 6
146 28196207 Correlation of Long-term Results of Imatinib in Advanced Gastrointestinal Stromal Tumors With Next-Generation Sequencing Results: Analysis of Phase 3 SWOG Intergroup Trial S0033. 2017 Jul 1 2
147 28260860 Antiproliferation effect of imatinib mesylate on MCF7, T-47D tumorigenic and MCF 10A nontumorigenic breast cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF genes. 2017 2
148 28334365 Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib: An Exploratory Analysis of a Randomized Clinical Trial. 2017 May 1 2
149 28334439 A phase 2 trial of dasatinib in patients with locally advanced or stage IV mucosal, acral, or vulvovaginal melanoma: A trial of the ECOG-ACRIN Cancer Research Group (E2607). 2017 Jul 15 5
150 28403213 M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells. 2017 6