Imatinib Mesylate

KIT proto-oncogene, receptor tyrosine kinase ; Homo sapiens







1113 Article(s)
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1 34709443 [Surgical and interdisciplinary treatment of gastrointestinal stromal tumors]. 2022 Jan 1
2 34775854 Vitreous hemorrhage: A rare ophthalmic adverse effect due to imatinib treatment. 2022 Apr 4
3 34983047 KIT Exon 9-Mutated Gastrointestinal Stromal Tumours: Biology and Treatment. 2022 1
4 35053574 Introduction of Mutant GNAQ into Endothelial Cells Induces a Vascular Malformation Phenotype with Therapeutic Response to Imatinib. 2022 Jan 14 2
5 35120552 GnRH antagonist weakens endometrial stromal cells growth ability by decreasing c-kit receptor expression. 2022 Feb 4 1
6 35174150 Noncoding RNAs in Drug Resistance of Gastrointestinal Stromal Tumor. 2022 1
7 35194937 Nintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours. 2022 Apr 1
8 35217782 New treatment strategies for advanced-stage gastrointestinal stromal tumours. 2022 May 2
9 35349049 Gastrointestinal Stromal Tumors: What Is the Best Sequence of TKIs? 2022 May 1
10 35487307 Tyrosine kinase inhibitors for the treatment of indolent systemic mastocytosis: Are we there yet? 2022 Jun 1
11 35585158 Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability. 2022 May 18 2
12 33030616 Apatinib exhibits synergistic effect with pyrotinib and reverses acquired pyrotinib resistance in HER2-positive gastric cancer via stem cell factor/c-kit signaling and its downstream pathways. 2021 Mar 1
13 33247506 c-KIT-ERK1/2 signaling activated ELK1 and upregulated carcinoembryonic antigen expression to promote colorectal cancer progression. 2021 Feb 1
14 33307872 New insights into the clinical management of advanced gastrointestinal stromal tumors. 2021 Mar 2
15 33389076 A new monoclonal antibody that blocks dimerisation and inhibits c-kit mutation-driven tumour growth. 2021 Apr 1
16 33402214 The management of metastatic GIST: current standard and investigational therapeutics. 2021 Jan 5 1
17 33422470 A Phase II Trial of Imatinib Mesylate as Maintenance Therapy for Patients With Newly Diagnosed C-kit-positive Acute Myeloid Leukemia. 2021 Feb 1
18 33524167 Systemic mastocytosis in adults: 2021 Update on diagnosis, risk stratification and management. 2021 Apr 1 1
19 33641024 Liquid Biopsy in Gastrointestinal Stromal Tumors: Ready for Prime Time? 2021 Feb 27 2
20 33670651 Rare Occurrence of Microsatellite Instability in Gastrointestinal Stromal Tumors. 2021 Feb 18 1
21 33673554 Type and Gene Location of KIT Mutations Predict Progression-Free Survival to First-Line Imatinib in Gastrointestinal Stromal Tumors: A Look into the Exon. 2021 Feb 27 2
22 33727226 Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors. 2021 May 1 4
23 33737510 Gastrointestinal stromal tumours. 2021 Mar 18 2
24 33743084 Surgical Management of Metastatic Gastrointestinal Stromal Tumors. 2021 Mar 20 1
25 33783002 Thymoquinone chemosensitizes human colorectal cancer cells to imatinib via uptake/efflux genes modulation. 2021 Jun 2
26 33848847 G-CSF promotes alloregulatory function of MDSCs through a c-Kit dependent mechanism. 2021 Jun 1
27 33947686 Ripretinib and MEK Inhibitors Synergize to Induce Apoptosis in Preclinical Models of GIST and Systemic Mastocytosis. 2021 Jul 1
28 34065883 Current Status and Prospects of Immunotherapy for Gynecologic Melanoma. 2021 May 12 1
29 34089444 Starting Imatinib at 400 mg Daily in Patients with Gastrointestinal Stromal Tumors Harboring KIT Exon 9 Mutations: A Retrospective, Multicenter Study. 2021 Jul 1
30 34236401 Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial. 2021 Sep 1 1
31 34298737 Immunotherapy Strategies for Gastrointestinal Stromal Tumor. 2021 Jul 14 1
32 34322383 Early and Next-Generation KIT/PDGFRA Kinase Inhibitors and the Future of Treatment for Advanced Gastrointestinal Stromal Tumor. 2021 1
33 34324512 Inhibition of PI3K and MAPK pathways along with KIT inhibitors as a strategy to overcome drug resistance in gastrointestinal stromal tumors. 2021 1
34 34359600 Combined Inhibition of AKT and KIT Restores Expression of Programmed Cell Death 4 (PDCD4) in Gastrointestinal Stromal Tumor. 2021 Jul 23 4
35 34376580 KITlow Cells Mediate Imatinib Resistance in Gastrointestinal Stromal Tumor. 2021 Oct 2
36 34398495 Gastrointestinal stromal tumors with BRAF gene fusions. A report of two cases showing low or absent KIT expression resulting in diagnostic pitfalls. 2021 Dec 1
37 34446510 Sustained response to imatinib in patient with extraskeletal myxoid chondrosarcoma and novel KIT mutation. 2021 Aug 26 1
38 34489967 Beyond the Driver Mutation: Immunotherapies in Gastrointestinal Stromal Tumors. 2021 1
39 34589354 Gastrointestinal Stromal Tumor With Chondrosarcomatous Dedifferentiation Following Imatinib Therapy. 2021 Aug 2
40 34621020 E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor. 2021 Dec 1
41 34889232 Imatinib mesylate in combination with pembrolizumab in patients with advanced KIT-mutant melanoma following progression on standard therapy: A phase I/II trial and study protocol. 2021 Dec 10 2
42 34917498 Case Report: Evolution of KIT D816V-Positive Systemic Mastocytosis to Myeloid Neoplasm With PDGFRA Rearrangement Responsive to Imatinib. 2021 1
43 34944576 Results of TETimaX Trial of Langerhans Cell Histiocytosis Treatment and Perspectives on the Role of Imatinib Mesylate in the Era of MAPK Signaling. 2021 Nov 24 2
44 31197522 Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors. 2020 Jan 1
45 31702819 Multidrug resistant gastrointestinal stromal tumor with multiple metastases to the skin and subcutaneous soft tissue: A case report and review of literature. 2020 Apr 1
46 31758409 Identifying Secondary Mutations in Chinese Patients with Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs) by Next Generation Sequencing (NGS). 2020 Jan 1
47 31776458 Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours. 2020 Feb 2
48 31892598 Recurrence-free Survival and Safety of Imatinib in Patients With Gastrointestinal Stromal Tumour (GIST) in Greece. 2020 Jan 1
49 32005261 ALK expressed in a gastrointestinal stromal tumor harboring PDGFRA p. D842V mutation:a case report. 2020 Jan 31 1
50 32082541 Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib. 2020 4