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30428773 | Farnesoid X Receptor Agonist GW4064 Inhibits Aromatase and ERβ Expression in Human Endometriotic Stromal Cells. | 2019 Aug |
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| 2 |
30902657 | Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I. | 2019 Jun 15 |
2 |
| 3 |
30920307 | FXR agonist GW4064 improves liver and intestinal pathology and alters bile acid metabolism in rats undergoing small intestinal resection. | 2019 Aug 1 |
1 |
| 4 |
28787755 | A rapid administration of GW4064 inhibits the NLRP3 inflammasome activation independent of farnesoid X receptor agonism. | 2017 Sep |
1 |
| 5 |
25499883 | Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists. | 2015 Jan 15 |
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| 6 |
25725071 | GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression. | 2015 May |
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| 7 |
25934227 | Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties. | 2015 Jul 1 |
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| 8 |
25400456 | GW4064, a farnesoid X receptor agonist, upregulates adipokine expression in preadipocytes and HepG2 cells. | 2014 Nov 14 |
1 |
| 9 |
23878601 | Regulation of DDAH1 as a Potential Therapeutic Target for Treating Cardiovascular Diseases. | 2013 |
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| 10 |
22579649 | Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand. | 2012 Oct 28 |
1 |
| 11 |
22583617 | E297G mutated bile salt export pump (BSEP) function enhancers derived from GW4064: structural development study and separation from farnesoid X receptor-agonistic activity. | 2012 Jun 15 |
1 |
| 12 |
23101941 | Unbinding pathways of GW4064 from human farnesoid X receptor as revealed by molecular dynamics simulations. | 2012 Nov 26 |
1 |
| 13 |
21319191 | Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis. | 2011 Mar |
1 |
| 14 |
21499302 | Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression. | 2011 Sep 29 |
1 |
| 15 |
21660973 | A formulation-enabled preclinical efficacy assessment of a farnesoid X receptor agonist, GW4064, in hamsters and cynomolgus monkeys. | 2011 Nov |
1 |
| 16 |
19410460 | Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064. | 2009 Jun 1 |
1 |
| 17 |
18755856 | Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity. | 2008 Nov |
1 |
| 18 |
15692145 | The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids. | 2005 May |
1 |