| 1 |
34570396 | Propofol suppresses cell proliferation in gastric cancer cells through NRF2-mediated polyol pathway. | 2022 Feb |
2 |
| 2 |
35388067 | Development and exploration of novel substituted thiosemicarbazones as inhibitors of aldose reductase via in vitro analysis and computational study. | 2022 Apr 6 |
3 |
| 3 |
35454074 | In Search of Differential Inhibitors of Aldose Reductase. | 2022 Mar 22 |
1 |
| 4 |
33109031 | Development of Aldose Reductase Inhibitors for the Treatment of Inflammatory Disorders and Cancer: Current Drug Design Strategies and Future Directions. | 2021 |
2 |
| 5 |
33906691 | Rhodanine-3-acetamide derivatives as aldose and aldehyde reductase inhibitors to treat diabetic complications: synthesis, biological evaluation, molecular docking and simulation studies. | 2021 Apr 27 |
2 |
| 6 |
33945128 | Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks. | 2021 |
2 |
| 7 |
34314916 | Development of coumarin-thiosemicarbazone hybrids as aldose reductase inhibitors: Biological assays, molecular docking, simulation studies and ADME evaluation. | 2021 Oct |
2 |
| 8 |
34677370 | Physiological and Pathological Roles of Aldose Reductase. | 2021 Sep 27 |
2 |
| 9 |
34768205 | Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase. | 2021 Dec |
2 |
| 10 |
32086945 | Elevated Fructose and Uric Acid Through Aldose Reductase Contribute to Experimental and Human Alcoholic Liver Disease. | 2020 Nov |
3 |
| 11 |
33069193 | Natural Compounds as Source of Aldose Reductase (AR) Inhibitors for the Treatment of Diabetic Complications: A Mini Review. | 2020 |
2 |
| 12 |
30551808 | Benzoxazinone-thiosemicarbazones as antidiabetic leads via aldose reductase inhibition: Synthesis, biological screening and molecular docking study. | 2019 Jun |
2 |
| 13 |
30818176 | Synthesis of new arylsulfonylspiroimidazolidine-2',4'-diones and study of their effect on stimulation of insulin release from MIN6 cell line, inhibition of human aldose reductase, sorbitol accumulations in various tissues and oxidative stress. | 2019 Apr 15 |
2 |
| 14 |
31811113 | Protective Effect of β-Glucogallin on Damaged Cataract Against Methylglyoxal Induced Oxidative Stress in Cultured Lens Epithelial Cells. | 2019 Dec 7 |
2 |
| 15 |
29693278 | Inhibition of C298S mutant of human aldose reductase for antidiabetic applications: Evidence from in silico elementary mode analysis of biological network model. | 2018 Aug |
1 |
| 16 |
29705708 | Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. | 2018 May 25 |
2 |
| 17 |
29863179 | Redox imbalance stress in diabetes mellitus: Role of the polyol pathway. | 2018 Mar |
1 |
| 18 |
27208686 | Increased sorbitol levels in the hypertrophic ligamentum flavum of diabetic patients with lumbar spinal canal stenosis. | 2017 May |
4 |
| 19 |
27894247 | Aldose Reductase as a Drug Target for Treatment of Diabetic Nephropathy: Promises and Challenges. | 2017 |
2 |
| 20 |
28302016 | Validation of TZD Scaffold as Potential ARIs: Pharmacophore Modeling, Atom-based 3D QSAR and Docking Studies. | 2017 |
2 |
| 21 |
28820747 | Involvement of hyperglycemia in the development of platelet procoagulant response: the role of aldose reductase and platelet swelling. | 2017 Sep |
2 |
| 22 |
30023751 | New Insights into the Catalytic Mechanism of Aldose Reductase: A QM/MM Study. | 2017 Sep 30 |
1 |
| 23 |
26349493 | Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases. | 2016 |
2 |
| 24 |
27190083 | Ranirestat has a stronger inhibitory activity on aldose reductase and suppresses inflammatory reactions in high glucose-exposed endothelial cells. | 2016 Jul |
1 |
| 25 |
27396410 | Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose Reductase Inhibitors for Diabetic Cataract. | 2016 |
1 |
| 26 |
27628063 | Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5. | 2016 Dec |
1 |
| 27 |
24903533 | Design, synthesis and evaluation of rhodanine derivatives as aldose reductase inhibitors. | 2015 Feb |
2 |
| 28 |
25315636 | Kinetic and molecular docking studies of loganin and 7-O-galloyl-D-sedoheptulose from Corni Fructus as therapeutic agents for diabetic complications through inhibition of aldose reductase. | 2015 Jun |
1 |
| 29 |
25998127 | Hyperglycemia Promotes Schwann Cell De-differentiation and De-myelination via Sorbitol Accumulation and Igf1 Protein Down-regulation. | 2015 Jul 10 |
1 |
| 30 |
26132779 | Aldose Reductase Mediates Transforming Growth Factor β2 (TGF-β2)-Induced Migration and Epithelial-To-Mesenchymal Transition of Lens-Derived Epithelial Cells. | 2015 Jul |
1 |
| 31 |
26163626 | Aldose Reductase Inhibitor Fidarestat as a Promising Drug Targeting Autophagy in Colorectal Carcinoma: a Pilot Study. | 2015 |
2 |
| 32 |
24236461 | Alkaloids as aldose reductase inhibitors, with special reference to berberine. | 2014 Mar |
1 |
| 33 |
24607578 | Development of novel pyrazolone derivatives as inhibitors of aldose reductase: an eco-friendly one-pot synthesis, experimental screening and in silico analysis. | 2014 Apr |
1 |
| 34 |
24991118 | Vegetables' juice influences polyol pathway by multiple mechanisms in favour of reducing development of oxidative stress and resultant diabetic complications. | 2014 Apr |
1 |
| 35 |
23850972 | Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians. | 2013 Oct |
1 |
| 36 |
23901876 | Discovery of new selective human aldose reductase inhibitors through virtual screening multiple binding pocket conformations. | 2013 Sep 23 |
1 |
| 37 |
24019949 | A new approach to control the enigmatic activity of aldose reductase. | 2013 |
1 |
| 38 |
22249747 | Pharmacophore modeling, molecular docking, and molecular dynamics simulation approaches for identifying new lead compounds for inhibiting aldose reductase 2. | 2012 Jul |
2 |
| 39 |
22565168 | High glucose levels induce inhibition of Na,K-ATPase via stimulation of aldose reductase, formation of microtubules and formation of an acetylated tubulin/Na,K-ATPase complex. | 2012 Aug |
1 |
| 40 |
22582044 | Aldose reductase, oxidative stress, and diabetic mellitus. | 2012 |
3 |
| 41 |
22844269 | Inhibition of aldose reductase by Gentiana lutea extracts. | 2012 |
1 |
| 42 |
20939801 | Aldose reductase / polyol inhibitors for diabetic retinopathy. | 2011 Mar 1 |
1 |
| 43 |
21319207 | Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors. | 2011 Jun |
1 |
| 44 |
19778627 | Aldose reductase: a novel therapeutic target for inflammatory pathologies. | 2010 Jan |
2 |
| 45 |
20218967 | 3D-QSAR Studies on a Series of 5-Arylidine-2, 4-Thiazolidinediones as Aldose Reductase Inhibitors: A Self-Organizing Molecular Field Analysis Approach. | 2010 Mar 11 |
2 |
| 46 |
20402658 | 3D-QSAR studies on a series of 5-arylidine-2, 4-thiazolidinediones as aldose reductase inhibitors: a self-organizing molecular field analysis approach. | 2010 Jan |
2 |
| 47 |
20466987 | Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model. | 2010 May 14 |
1 |
| 48 |
20520742 | Elevated Serum Sorbitol and not Fructose in Type 2 Diabetic Patients. | 2010 May 4 |
3 |
| 49 |
19224447 | Localization of the polyol pathway in the human kidney. | 2009 Apr |
2 |
| 50 |
19301313 | Structure-based optimization of aldose reductase inhibitors originating from virtual screening. | 2009 May |
2 |