Phenobarbital

UDP glucuronosyltransferase family 1 member A1 ; Homo sapiens







28 Article(s)
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1 33551819 Transporter Gene Regulation in Sandwich Cultured Human Hepatocytes Through the Activation of Constitutive Androstane Receptor (CAR) or Aryl Hydrocarbon Receptor (AhR). 2020 1
2 31142299 A novel UGT1A1 gene mutation causing severe unconjugated hyperbilirubinemia: a case report. 2019 May 29 1
3 26781906 Three-dimensional polyacrylamide gel-based DNA microarray method effectively identifies UDP-glucuronosyltransferase 1A1 gene polymorphisms for the correct diagnosis of Gilbert's syndrome. 2016 Mar 1
4 27099654 Management of pregnancy in Crigler Najjar syndrome type 2. 2016 Apr 18 1
5 25751380 [Clinical features and gene mutation profiles of patients with chronic hepatitis B and Gilbert's syndrome]. 2015 Jan 1
6 24865931 Combined effects of the UGT1A1 and OATP2 gene polymorphisms as major risk factor for unconjugated hyperbilirubinemia in Indian neonates. 2014 Aug 15 1
7 20201778 Development of a UGT1A1 reporter gene assay for induction studies: correlation between reporter gene data and regulation of UGT1A1 in human hepatocytes. 2010 Jan 1
8 20979879 [Clinical and genetic analyses of UGT1A1 gene from a Chinese family with Gilbert's syndrome]. 2010 Jun 22 1
9 19541828 Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver. 2009 Sep 4
10 18172616 Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter. 2008 Jun 2
11 18328680 Coordinated induction of drug transporters and phase I and II metabolism in human liver slices. 2008 Apr 23 1
12 18558634 Coexpression of gene polymorphisms involved in bilirubin production and metabolism. 2008 Jul 1
13 17259171 Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice. 2007 Mar 23 2
14 17599282 Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture. 2007 Jul 2
15 16424820 Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes. 2006 Feb 3
16 15557560 Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1. 2005 Mar 1
17 15771689 Neonatal hyperbilirubinemia and the bilirubin uridine diphosphate-glucuronosyltransferase gene: the common -3263T > G mutation of phenobarbital response enhancer module is not associated with the neonatal hyperbilirubinemia in Japanese. 2005 Apr 1
18 15849716 Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers. 2005 2
19 15864124 Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity. 2005 Jan 2
20 15881424 Isolated hepatocyte transplantation for Crigler-Najjar syndrome type 1. 2005 1
21 14978227 Identification of novel alternative splice variants of human constitutive androstane receptor and characterization of their expression in the liver. 2004 Mar 2
22 15382119 Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. 2004 Oct 1
23 11906189 Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia. 2002 Mar 29 1
24 12464801 Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. 2002 Dec 1
25 11343253 The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR. 2001 May 4
26 8869742 Regulation of the human bilirubin UDP-glucuronosyltransferase gene. 1996 1
27 8968658 Pharmacokinetic interactions between antiepileptic drugs. Clinical considerations. 1996 Dec 1
28 1900006 Induction of alkoxyresorufin O-dealkylases and UDP-glucuronosyl transferase by phenobarbital and 3-methylcholanthrene in primary cultures of porcine ciliary epithelial cells. 1991 Feb 15 4