Cyclosporine

peptidylprolyl isomerase G ; Homo sapiens







45 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35242122 Emerging Roles of Cyclophilin A in Regulating Viral Cloaking. 2022 3
2 33548873 Hepatic in vitro metabolism of peptides; Comparison of human liver S9, hepatocytes and Upcyte hepatocytes with cyclosporine A, leuprorelin, desmopressin and cetrorelix as model compounds. 2021 Mar 20 1
3 25193101 Enzymatic and thermodynamic analysis of calcineurin inhibition by RCAN1. 2015 Jan 2
4 22902549 HCV NS5A and IRF9 compete for CypA binding. 2013 Jan 2
5 20451281 HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors. 2010 Jul 2
6 19499554 The thermodynamic influence of trapped water molecules on a protein-ligand interaction. 2009 1
7 19503092 Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells. 2009 Aug 6 2
8 19659609 Identification of cellular and viral factors related to anti-hepatitis C virus activity of cyclophilin inhibitor. 2009 Oct 5
9 18095667 Solution structures of cyclosporin a and its complex with dysprosium(III) in SDS micelles: NMR and molecular dynamics studies. 2008 Jan 24 3
10 17609268 Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses. 2007 Sep 2
11 17707777 Different roles of Loop 7 in inhibition of calcineurin. 2007 Oct 19 1
12 16299069 1H and 13C-NMR and molecular dynamics studies of cyclosporin a interacting with magnesium(II) or cerium(III) in acetonitrile. Conformational changes and cis-trans conversion of peptide bonds. 2006 Feb 15 1
13 15832403 Exo-mechanism proximity-accelerated alkylations: investigations of linkers, electrophiles and surface mutations in engineered cyclophilin-cyclosporin systems. 2005 May 1
14 16354247 A study of gene expression of cyclophilin in childhood refractory nephrotic syndrome and its clinical significance. 2005 Dec 1
15 15353287 Crystal structures of cyclophilin and its partners. 2004 Sep 1 2
16 11694517 Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis. 2002 Feb 8 4
17 12357034 Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin. 2002 Oct 15 3
18 10966874 Archaeal peptidyl prolyl cis-trans isomerases (PPIases). 2000 Sep 1 3
19 10189702 Characterization of cytosolic cyclophilin from guard cells of Vicia faba L. 1999 Jan 1
20 10486755 Interaction of cyclophilin and cyclosporins monitored by affinity capillary electrophoresis. 1999 Aug 20 6
21 9472618 Inhibition of vaccinia virus replication by cyclosporin A analogues correlates with their affinity for cellular cyclophilins. 1998 Feb 2
22 9709036 Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity. 1998 Sep 2
23 9075347 Characterization of calcineurin from Hymenolepis microstoma and H. diminuta and its interaction with cyclosporin A. 1997 Mar 7
24 8679570 Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+]. 1996 Jun 25 2
25 8939689 Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization. 1996 Sep 1
26 9010851 [Transplantation immunology and immunosuppressive drug]. 1996 Nov 1
27 7529995 Time-dependent inhibition of peptidylprolyl cis-trans-isomerases by FK506 is probably due to cis-trans isomerization of the inhibitor's imide bond. 1995 Jan 1 1
28 7524680 pH titration of the histidine residues of cyclophilin and FK506 binding protein in the absence and presence of immunosuppressant ligands. 1994 Nov 16 3
29 8031755 Human cyclophilin C: primary structure, tissue distribution, and determination of binding specificity for cyclosporins. 1994 Jul 12 2
30 8075536 Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex. 1994 Jul 3
31 8075981 Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A. 1994 Jan 15 2
32 8312269 Solution conformation of a cyclophilin-bound proline isomerase substrate. 1994 Feb 15 4
33 7509138 The mechanism of action of FK-506 and cyclosporin A. 1993 Nov 30 1
34 7686148 Specific interaction of the cyclophilin-cyclosporin complex with the B subunit of calcineurin. 1993 Jul 5 6
35 1628422 Comparison of the properties of the CsA analogs monoacetyl CyC (o-acetyl-threonine2 cyclosporin) and methyl-alanyl CsA (N-methyl-L-alanyl6 cyclosporin); monoacetyl cyclosporin is immunosuppressive without binding to cyclophilin. 1992 Jul 7
36 1705513 The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. 1991 Feb 4
37 1743298 1H, 13C and 15N backbone assignments of cyclophilin when bound to cyclosporin A (CsA) and preliminary structural characterization of the CsA binding site. 1991 Dec 2 6
38 1744118 The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms. 1991 Dec 5 5
39 1871809 The immunochemical distribution of cyclophilin in normal mammalian tissues. 1991 Aug 4
40 1917291 Conformation of MeAla6-cyclosporin A by NMR. Relationship of sidechain orientation of the MeBmt-1, MeLeu-9, and MeLeu-10 residues to immunosuppressive activity. 1991 May 2
41 2004448 Determination of cyclosporine by a competitive binding assay with cyclophilin. 1991 Mar 9
42 2026447 Distribution of the cyclosporine binding protein cyclophilin in human tissues. 1991 Mar 5
43 2054356 NMR studies of [U-13C]cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding. 1991 Jul 2 3
44 2966482 A study of the correlation between cyclophilin binding and in vitro immunosuppressive activity of cyclosporine A and analogues. 1988 Apr 1
45 3043795 Cyclophilin, a primary molecular target for cyclosporine. Structural and functional implications. 1988 Aug 8