Imatinib Mesylate

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







23 Article(s)
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1 33197900 Application of ZnO/CNT@Fe3O4nanocomposite in amplifying the anti-leukemic effects of Imatinib: a novel strategy to adjuvant therapy in chronic myeloid leukemia. 2021 Mar 5 2
2 34843676 Simvastatin potentiates the cell-killing activity of imatinib in imatinib-resistant chronic myeloid leukemia cells mainly through PI3K/AKT pathway attenuation and Myc downregulation. 2021 Dec 15 1
3 32430012 Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells. 2020 May 19 3
4 30738487 [Research Progress of C-Myc in Chronic Myelogenous Leukemia --Review]. 2019 Feb 2
5 29423056 Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia. 2018 Jan 9 5
6 30153828 The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells. 2018 Aug 28 1
7 30687103 A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells. 2018 1
8 27550925 Original Research: Featured Article: Imatinib mesylate (Gleevec) inhibits Notch and c-Myc signaling: Five-day treatment permanently rescues mammary development. 2017 Jan 1
9 27825294 Downregulation of miR-451 in Tunisian chronic myeloid leukemia patients: potential implication in imatinib resistance. 2017 May 2
10 28069548 Long noncoding RNA HULC promotes cell proliferation by regulating PI3K/AKT signaling pathway in chronic myeloid leukemia. 2017 Apr 5 1
11 27281222 Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells. 2016 Jun 16 1
12 25647305 Novel agent nitidine chloride induces erythroid differentiation and apoptosis in CML cells through c-Myc-miRNAs axis. 2015 1
13 25765543 Second generation tyrosine kinase inhibitors prevent disease progression in high-risk (high CIP2A) chronic myeloid leukaemia patients. 2015 Jul 1
14 26248946 Silencing of miR-21 sensitizes CML CD34+ stem/progenitor cells to imatinib-induced apoptosis by blocking PI3K/AKT pathway. 2015 Oct 1
15 22710719 MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.). 2013 Apr 25 8
16 22842456 Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562. 2012 Aug 24 5
17 21460180 MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib. 2011 May 4
18 20807813 A specific need for CRKL in p210BCR-ABL-induced transformation of mouse hematopoietic progenitors. 2010 Sep 15 1
19 19602047 Transcriptional regulation of survivin by c-Myc in BCR/ABL-transformed cells: implications in anti-leukaemic strategy. 2009 Aug 1
20 18086564 Mechanisms for the proliferation of eosinophilic leukemia cells by FIP1L1-PDGFRalpha. 2008 Feb 22 1
21 18429956 Activity of a novel Aurora kinase inhibitor against the T315I mutant form of BCR-ABL: in vitro and in vivo studies. 2008 Jun 1
22 15517875 Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect. 2004 Sep-Oct 1
23 12370803 Jak2 is involved in c-Myc induction by Bcr-Abl. 2002 Oct 17 1