Lactic Acid

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







28 Article(s)
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1 35096062 Exosome-Mediated miR-4792 Transfer Promotes Bladder Cancer Cell Proliferation via Enhanced FOXC1/c-Myc Signaling and Warburg Effect. 2022 2
2 33894159 Uncovering metabolic reservoir cycles in MYC-transformed lymphoma B cells using stable isotope resolved metabolomics. 2021 Nov 1 1
3 34133930 MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages. 2021 Jun 15 1
4 32433492 Lactate preconditioning promotes a HIF-1α-mediated metabolic shift from OXPHOS to glycolysis in normal human diploid fibroblasts. 2020 May 20 1
5 29932015 STAT3/c-Myc Axis-Mediated Metabolism Alternations of Inflammation-Related Glycolysis Involve with Colorectal Carcinogenesis. 2019 Apr 1
6 31555797 Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane. 2019 Dec 31 1
7 31804603 Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc. 2019 Dec 5 1
8 32010625 Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells. 2019 2
9 28822229 Vasculogenesis and angiogenesis initiation under normoxic conditions through Wnt/β-catenin pathway in gliomas. 2018 Jan 26 1
10 29545400 Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate. 2018 Jun 1
11 30054337 Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma. 2018 Sep 15 1
12 28749470 miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer. 2017 Jul 27 1
13 28812580 Lactate dehydrogenase activity drives hair follicle stem cell activation. 2017 Sep 1
14 26636483 Lactate promotes glutamine uptake and metabolism in oxidative cancer cells. 2016 1
15 26021472 The c-Myc-LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer. 2015 Jul 1
16 24285728 Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. 2014 Feb 1 2
17 23296385 ETA: robust software for determination of cell specific rates from extracellular time courses. 2013 Jun 1
18 23639941 MEK1/2 inhibition decreases lactate in BRAF-driven human cancer cells. 2013 Jul 1 1
19 23897900 Molecular Pathways: Targeting MYC-induced metabolic reprogramming and oncogenic stress in cancer. 2013 Nov 1 1
20 22225880 Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. 2012 Jan 4 1
21 21969607 Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells. 2011 Dec 1
22 20018866 Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition. 2010 Mar 5 1
23 20133848 Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. 2010 Feb 2 1
24 17785433 Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. 2007 Nov 1
25 18811052 The interplay between MYC and HIF in the Warburg effect. 2007 2
26 10823814 Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. 2000 Jul 21 1
27 10100870 Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression. 1999 Mar 12 6
28 9192621 c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. 1997 Jun 24 2