Tetradecanoylphorbol Acetate

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







90 Article(s)
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1 27520485 Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1. 2016 Oct 1 1
2 25908095 REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway. 2015 Apr 24 1
3 23562609 MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein α. 2013 Aug 1
4 19526458 Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis. 2009 Nov 1
5 15949478 PKC delta-induced activation of MAPK pathway is required for bFGF-stimulated proliferation of coronary smooth muscle cells. 2005 Jul 1 2
6 14757441 Protein expression of PDZ-binding kinase is up-regulated in hematologic malignancies and strongly down-regulated during terminal differentiation of HL-60 leukemic cells. 2004 Jan-Feb 1
7 15479821 Inhibition of Epstein-Barr virus (EBV) reactivation by short interfering RNAs targeting p38 mitogen-activated protein kinase or c-myc in EBV-positive epithelial cells. 2004 Nov 4
8 12688321 Activation of protein kinase C enhances TNF-alpha-induced differentiation by preventing apoptosis via rapid up-regulation of c-Myc protein expression in HL-60 cells. 2003 Mar 3
9 12910377 Terminal differentiation in vitro of patient-derived post-TMD megakaryoblastic AML cells. 2003 Aug 2
10 12091391 A novel myc target gene, mina53, that is involved in cell proliferation. 2002 Sep 20 1
11 12118374 The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation. 2002 Jul 25 1
12 11598794 Down-modulation of c-myc expression by phorbol ester protects CEM T leukaemia cells from starvation-induced apoptosis: role of ornithine decarboxylase and polyamines. 2001 Oct 1
13 11710937 Effects of 12-O-tetradecanoyl-phorbol-13-acetate [corrected] and sodium lauryl sulfate on the production and expression of cytokines and proto-oncogenes in photoaged and intrinsically aged human keratinocytes. 2001 Nov 1
14 10849366 Co-induction of Mad1 and c-Myc in activated normal B lymphocytes. 2000 Jun 2
15 10918054 Activation of protein kinase C induces nuclear translocation of RFX1 and down-regulates c-myc via an intron 1 X box in undifferentiated leukemia HL-60 cells. 2000 Oct 13 3
16 10931849 Regulation of c-myc mRNA decay in vitro by a phorbol ester-inducible, ribosome-associated component in differentiating megakaryoblasts. 2000 Oct 27 2
17 10027304 Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc. 1999 Feb 1
18 10319992 Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells. 1999 Apr 3
19 10339499 Posttranslational regulation of Myc function in response to phorbol ester/interferon-gamma-induced differentiation of v-Myc-transformed U-937 monoblasts. 1999 Jun 1 8
20 10397677 Protein kinase C mediates basic fibroblast growth factor-induced proliferation through mitogen-activated protein kinase in coronary smooth muscle cells. 1999 Jul 2
21 10511314 Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation. 1999 Sep 2
22 9514905 The protein kinase C activator, phorbol ester, elicits disparate functional responses in androgen-sensitive and androgen-independent human prostatic cancer cells. 1998 Mar 6 1
23 9615391 Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937). 1998 May 2
24 9000576 Defects in p21WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells. 1997 Jan 15 3
25 9057647 Constitutive activation of U937 promonocytic cell clones selected for their resistance to parvovirus H-1 infection. 1997 Mar 1 2
26 9202001 Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. 1997 Jul 4 1
27 9301678 Differential effects of phorbol ester on signaling and gene expression in human leukemia cells. 1997 Jul 2
28 9341140 Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells. 1997 Oct 24 2
29 9378547 Aggressive tumor growth of human TUR leukemia cells is associated with high levels of c-myc expression and down-regulation of p20-max. 1997 Sep 17 1
30 10322942 Inhibition of harringtonine-induced apoptosis by tetradecanoylphorbol acetate in human leukemia HL-60 cells. 1997 Sep 1
31 8778231 Expression of the c-myc gene in human adrenals: regulation by adrenocorticotropin in primary cultures. 1996 Mar 3
32 8870649 Early response gene signalling in bryostatin-stimulated primary B chronic lymphocytic leukaemia cells in vitro. 1996 Oct 1 2
33 7500645 Differential expression of c-myc, max and mxi1 in human myeloid leukemia cells during retrodifferentiation and cell death. 1995 Oct 2
34 7554401 Defective expression of early activation genes in cartilage-hair hypoplasia (CHH) with severe combined immunodeficiency (SCID). 1995 Oct 1
35 7794791 A direct role of transcription factor E2F in c-myc gene expression during granulocytic and macrophage-like differentiation of HL60 cells. 1995 Mar 1
36 21043585 AP-1/C-jun and C-myc Regulation During Megakaryocytic Differentiation of a Human Bi-potential Growth-factor-dependent Cell Line. 1995 5
37 7841543 Tumor-promoting phorbol ester-induced cell death and gene expression in a human prostate adenocarcinoma cell line. 1994 1
38 7847852 Increased resistance to apoptosis associated with HL-60 myeloid differentiation status. 1994 Sep-Oct 1
39 7849624 Regulation of cell growth and the c-myc proto-oncogene expression by phorbol ester 12-0-tetradecanoyl phorbol-13-acetate (TPA) in the androgen-independent human prostatic JCA-1 cells. 1994 Aug 3
40 7864662 Changes in oncogene mRNA expression during human keratinocyte differentiation. 1994 3
41 8183547 Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts. 1994 Jun 1
42 9397949 Identification of the estrogen sensitive marker in human endometrial carcinoma RL95-2 cells. 1994 May 2
43 7694866 Characterization of interleukin-7-induced changes in tyrosine phosphorylation and c-myc gene expression in normal human T cells. 1993 Dec 4
44 8097865 Regulation of transglutaminase type I expression in squamous differentiating rabbit tracheal epithelial cells and human epidermal keratinocytes: effects of retinoic acid and phorbol esters. 1993 Mar 1
45 8100719 Functional abnormalities of CD8+ T cells define a unique subset of patients with common variable immunodeficiency. 1993 Jul 1 1
46 8231250 Down-regulation of c-myc gene is not obligatory for growth inhibition and differentiation of human myeloid leukemia cells. 1993 Nov 1
47 8352523 Modulation of c-myc, c-myb, c-fos, c-sis and c-fms proto-oncogene expression and of CSF-1 transcripts and protein by phorbol diester in human malignant histiocytosis DEL cell line with 5q 35 break point. 1993 Jul-Aug 1
48 8518229 Altered cytoplasmic/nuclear distribution of the c-myc protein in differentiating ML-1 human myeloid leukemia cells. 1993 May 2
49 1450490 HL-60 cells isolated for resistance to vincristine are defective in 12-O-tetradecanoylphorbol-13-acetate induced differentiation and the formation of a functional AP-1 complex. 1992 1
50 1472905 Modification of proto-oncogene expression by phorbol esters in human dermal microvascular endothelial cells. 1992 Nov 1