Tretinoin

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







85 Article(s)
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1 35468223 Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all-trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia. 2022 Apr 25 4
2 34236140 All-trans retinoic acid induces leukemia resistance to NK cell cytotoxicity by down-regulating B7-H6 expression via c-Myc signaling. 2021 Jan 4
3 32536235 Arsenic trioxide and all-trans retinoic acid suppress the expression of FLT3-ITD. 2020 Nov 1
4 32927768 Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition. 2020 Sep 10 4
5 31264378 The c-Myc-regulated miR-17-92 cluster mediates ATRA-induced APL cell differentiation. 2019 Dec 1
6 29699387 The Bromodomain Inhibitor JQ1 Enhances the Responses to All-trans Retinoic Acid in HL-60 and MV4-11 Leukemia Cells. 2018 May 30 1
7 30123134 Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer. 2018 2
8 27182202 Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation. 2016 1
9 27486764 C-Myc functions as a competing endogenous RNA in acute promyelocytic leukemia. 2016 Aug 30 2
10 26248086 Analysis of dysplasia in patients with Barrett's esophagus based on expression pattern of 90 genes. 2015 Nov 1
11 26545364 Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia. 2015 Nov 6 2
12 24516348 NLS-RARα promotes proliferation and inhibits differentiation in HL-60 cells. 2014 2
13 24646031 Role of cell cycle regulatory molecules in retinoic acid- and vitamin D3-induced differentiation of acute myeloid leukaemia cells. 2014 Jun 1
14 25072246 A PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiation. 2014 1
15 25127121 Inhibition of c-Myc overcomes cytotoxic drug resistance in acute myeloid leukemia cells by promoting differentiation. 2014 2
16 23528537 Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a. 2013 Jun 1
17 23562609 MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein α. 2013 Aug 1
18 23588859 c-myc but not Hif-1α-dependent downregulation of VEGF influences the proliferation and differentiation of HL-60 cells induced by ATRA. 2013 Jun 2
19 22341854 TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid. 2012 Oct 2
20 22407764 The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer. 2012 Jul 2
21 23063977 All-trans retinoic acid combined with 5-Aza-2'-deoxycitidine induces C/EBPα expression and growth inhibition in MLL-AF9-positive leukemic cells. 2012 Nov 16 2
22 22020439 E-box-independent regulation of transcription and differentiation by MYC. 2011 Oct 23 1
23 19550295 Effect of cytotoxic agents and retinoic acid on Myc-N protein expression in neuroblastoma. 2010 Jan 2
24 20538039 Proteomic approach reveals novel targets for retinoic acid-mediated therapy of thyroid carcinoma. 2010 Aug 30 2
25 20723292 [Enhancement of all-trans retinoic acid induced HL-60 leukemia cell differentiation by human umbilical cord mesenchymal stem cells]. 2010 Aug 2
26 19060179 Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell lines. 2009 Mar 3
27 19115248 Effect of tamoxifen and retinoic acid on bradykinin induced proliferation in MCF-7 cells. 2009 Feb 15 2
28 19324018 All-trans retinoic acid induces Thrombospondin-1 expression in acute promyelocytic leukemia cells though down-regulation of its transcription repressor, c-MYC oncoprotein. 2009 May 15 6
29 19507250 Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells. 2009 Oct 1 1
30 17706770 Role of Myc in differentiation and apoptosis in HL60 cells after exposure to arsenic trioxide or all-trans retinoic acid. 2008 Feb 2
31 18026954 Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells. 2008 Mar 1
32 18642056 Enhancement in alpha-tocopherol succinate-induced apoptosis by all-trans-retinoic acid in primary leukemic cells: role of antioxidant defense, Bax and c-myc. 2008 Dec 1
33 17389641 Orphan nuclear receptor TR2, a mediator of preadipocyte proliferation, is differentially regulated by RA through exchange of coactivator PCAF with corepressor RIP140 on a platform molecule GRIP1. 2007 3
34 17453147 All-trans-retinoic acid induces cell growth arrest in a human medulloblastoma cell line. 2007 Sep 1
35 15770638 Analysis of telomerase activity and RNA expression in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid. 2006 Apr 1
36 16800923 [Effect of aminopeptidase inhibitor on differentiation induction activity of all-trans retinoic acid in human acute promyelocytic leukemia NB4 cells and its mechanism]. 2006 Jun 4
37 16054129 Retinoic acid-induced downmodulation of telomerase activity in human cancer cells. 2005 Oct 1
38 15589822 c-Myc-mediated expression of nucleophosmin/B23 decreases during retinoic acid-induced differentiation of human leukemia HL-60 cells. 2004 Dec 17 2
39 12637327 Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells. 2003 Jul 1 2
40 12955881 Retinoic acid modulates the cell-cycle in fetal rat hepatocytes and HepG2 cells by regulating cyclin-cdk activities. 2003 Jun 1
41 11877298 Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1). 2002 Mar 15 4
42 12513735 [Study on telomerase activity and expression of hTERT, c-myc and bcl-2 during terminal differentiation of HL-60 cells induced by retinoic acid]. 2002 Oct 1
43 10642512 Induction of Myc-intron-binding polypeptides MIBP1 and RFX1 during retinoic acid-mediated differentiation of haemopoietic cells. 2000 Feb 1 3
44 10689181 Nuclear topography of the c-myc gene in human leukemic cells. 2000 Feb 22 2
45 10760826 Retinoic acid induces persistent, RARalpha-mediated anti-proliferative responses in Epstein-Barr virus-immortalized b lymphoblasts carrying an activated C-MYC oncogene but not in Burkitt's lymphoma cell lines. 2000 May 1 1
46 10896783 Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells. 2000 Aug 1 1
47 10984118 A combination treatment of c-myc antisense DNA with all-trans-retinoic acid inhibits cell proliferation by downregulating c-myc expression in small cell lung cancer. 2000 Aug 5
48 11776079 c-myc gene inactivation during induction of nasopharyngeal carcinoma cells with retinoic acid. 2000 Sep 3
49 10074929 Retinoic acid-mediated growth inhibition of small cell lung cancer cells is associated with reduced myc and increased p27Kip1 expression. 1999 Mar 15 1
50 12548778 [Regulation of cell cycle by retinoic acid in gastric cancer cells]. 1999 Jun 1