Simvastatin

tumor necrosis factor ; Mus musculus







29 Article(s)
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1 35618653 A ROS-Responsive Simvastatin Nano-Prodrug and its Fibronectin-Targeted Co-Delivery System for Atherosclerosis Treatment. 2022 Jun 8 1
2 33183460 Preparation of Simvastatin Loaded Nanostructured Lipid Carriers and Its Therapeutic Effect on Patients with Severe Acute Lung Injury. 2021 Feb 1 1
3 34830364 Statins and Bempedoic Acid: Different Actions of Cholesterol Inhibitors on Macrophage Activation. 2021 Nov 19 2
4 32016638 Simvastatin Improves Behavioral Disorders and Hippocampal Inflammatory Reaction by NMDA-Mediated Anti-inflammatory Function in MPTP-Treated Mice. 2020 Oct 2
5 32387414 Simvastatin attenuated sickness behavior and fever in a murine model of endotoxemia. 2020 Aug 1 1
6 30699879 Simvastatin prevents and ameliorates depressive behaviors via neuroinflammatory regulation in mice. 2019 Feb 15 1
7 29421861 Simvastatin protects against acetaminophen-induced liver injury in mice. 2018 Feb 1
8 29604489 Attenuation of TNF-induced neutrophil adhesion by simvastatin is associated with the inhibition of Rho-GTPase activity, p50 activity and morphological changes. 2018 May 1
9 31949780 Simvastatin inhibits inflammatory response in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages through the microRNA-22/Cyr61 axis. 2018 1
10 26701313 Simvastatin and a Plant Galactolipid Protect Animals from Septic Shock by Regulating Oxylipin Mediator Dynamics through the MAPK-cPLA2 Signaling Pathway. 2016 May 1
11 26824358 Correction: Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. 2016 1
12 24950285 Simvastatin reduces burn injury-induced splenic apoptosis via downregulation of the TNF-α/NF-κB pathway. 2015 May 3
13 25848815 Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation. 2015 Feb 14 1
14 26625143 Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. 2015 1
15 24912811 Simvastatin inhibits inflammation in ischemia-reperfusion injury. 2014 Oct 1
16 23275311 Simvastatin protects hepatocytes from apoptosis by suppressing the TNF-α/caspase-3 signaling pathway in mice with burn injury. 2013 Jun 6
17 23290865 Statins directly suppress cytokine production in murine intraepithelial lymphocytes. 2013 Feb 1
18 24040034 Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages. 2013 1
19 22102723 Deciphering the pathways of death of Histoplasma capsulatum-infected macrophages: implications for the immunopathogenesis of early infection. 2012 Jan 1 1
20 22939729 Can statins reduce the inflammatory response associated with preterm birth in an animal model? 2012 Sep 3
21 19631345 Simvastatin attenuates hepatic sensitization to lipopolysaccharide after partial hepatectomy. 2010 Aug 2
22 19730988 Simvastatin attenuates TNF-alpha-induced growth inhibition and apoptosis in murine osteoblastic MC3T3-E1 cells. 2010 Feb 1
23 18310456 Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway. 2008 Mar 10
24 18504409 HMG-CoA reductase inhibitor simvastatin inhibits proinflammatory cytokine production from murine mast cells. 2008 3
25 18981156 Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. 2008 Nov 15 1
26 19080365 Simvastatin attenuates bleomycin-induced pulmonary fibrosis in mice. 2008 Sep 20 2
27 17178392 Simvastatin inhibits NF-kappaB signaling in intestinal epithelial cells and ameliorates acute murine colitis. 2007 Feb 2
28 16321392 Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages. 2006 Sep 1
29 15777746 Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice. 2005 Mar 10 1