dinaciclib

cyclin dependent kinase 9 ; Homo sapiens







14 Article(s)
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1 34972202 Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study. 2022 Feb 22 1
2 33686114 Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells. 2021 Mar 8 1
3 32375399 Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib. 2020 May 4 1
4 32558295 Vulnerability of drug-resistant EML4-ALK rearranged lung cancer to transcriptional inhibition. 2020 Jul 7 1
5 28361959 Dinaciclib potently suppresses MCL-1 and selectively induces the cell death in human iPS cells without affecting the viability of cardiac tissue. 2017 Mar 31 2
6 26766294 Overview of CDK9 as a target in cancer research. 2016 1
7 27378523 Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity. 2016 Jul 5 4
8 27486754 Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer. 2016 Aug 30 2
9 25395429 Dinaciclib, a novel CDK inhibitor, demonstrates encouraging single-agent activity in patients with relapsed multiple myeloma. 2015 Jan 15 1
10 25578475 CDK9 inhibition by dinaciclib potently suppresses Mcl-1 to induce durable apoptotic responses in aggressive MYC-driven B-cell lymphoma in vivo. 2015 Jun 1
11 25882699 Synergistic induction of apoptosis in high-risk DLBCL by BCL2 inhibition with ABT-199 combined with pharmacologic loss of MCL1. 2015 Aug 1
12 25962959 Cyclin-dependent kinase inhibitor dinaciclib potently synergizes with cisplatin in preclinical models of ovarian cancer. 2015 Jun 20 1
13 25217392 Clinical study of the novel cyclin-dependent kinase inhibitor dinaciclib in combination with rituximab in relapsed/refractory chronic lymphocytic leukemia patients. 2014 Nov 1
14 23053255 Effect of aprepitant on the pharmacokinetics of the cyclin-dependent kinase inhibitor dinaciclib in patients with advanced malignancies. 2012 Dec 1