Glucuronides

glucuronidase, beta ; Rattus norvegicus







58 Article(s)
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1 29078076 Involvement of bilitranslocase and beta-glucuronidase in the vascular protection by hydroxytyrosol and its glucuronide metabolites in oxidative stress conditions. 2018 Jan 1
2 22473491 Oral coadministration of β-glucuronidase to increase exposure of extensively glucuronidated drugs that undergo enterohepatic recirculation. 2012 Jul 2
3 19217234 Plasma pharmacokinetics, tissue distribution and excretion study of 6-gingerol in rat by liquid chromatography-electrospray ionization time-of-flight mass spectrometry. 2009 May 1 1
4 16850523 Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis. 2007 Mar-Apr 1
5 17473444 Metabolism of FPP-3, an anti-inflammatory propenone compound, in rat by liquid chromatography-electrospray ionization tandem mass spectrometry. 2007 May 1
6 17660508 Beta-glucuronidase in human intestinal microbiota is necessary for the colonic genotoxicity of the food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in rats. 2007 Nov 1
7 16912565 Effect of ginger on bacterial enzymes in 1,2-dimethylhydrazine induced experimental colon carcinogenesis. 2006 Oct 1
8 15026282 Effect of coconut cake on the bacterial enzyme activity in 1,2-dimethyl hydrazine induced colon cancer. 2004 Apr 1
9 15177071 Quantitative analysis of cresol and its metabolites in biological materials and distribution in rats after oral administration. 2004 Mar 1
10 12969155 Comparative kinetics of the uremic toxin p-cresol versus creatinine in rats with and without renal failure. 2003 Oct 1
11 14595593 Fenugreek affects the activity of beta-glucuronidase and mucinase in the colon. 2003 Nov 1
12 11353756 Toxicokinetics and metabolism of 1,2-diethylbenzene in male Sprague Dawley rats--part 2: evidence for in vitro and in vivo stereoselectivity of 1,2-diethylbenzene metabolism. 2001 Jun 1
13 11764004 Rearrangement of diflunisal acyl glucuronide into its beta-glucuronidase-resistant isomers facilitates transport through the small intestine to the colon of the rat. 2001 Nov 21 1
14 10766370 Determination of the kinetics of rat UDP-glucuronosyltransferases (UGTs) in liver and intestine using HPLC. 2000 Apr 3
15 11011787 A novel efficient method to identify beta-glucuronidase activity in rat small intestine. 2000 Sep-Oct 1
16 10550890 Stereoselectivity of the phase-II-metabolism of the H1 antihistaminic drug dimethindene investigated by capillary electrophoresis. 1999 1
17 10570029 Toxicokinetics of 1,2-diethylbenzene in male Sprague-Dawley rats-part 1: excretion and metabolism of [(14)C]1,2-diethylbenzene. 1999 Dec 1
18 9720607 Influence of spices on the bacterial (enzyme) activity in experimental colon cancer. 1998 Aug 1
19 9766878 Determination of naringenin and its glucuronide conjugate in rat plasma and brain tissue by high-performance liquid chromatography. 1998 Sep 4 1
20 9028040 The role of microsomal beta-glucuronidase in ascorbic acid biosynthesis stimulated by xenobiotics in rats. 1997 Jan 1
21 9054596 Induction of a rat liver benzo[a]pyrene-trans-7,8-dihydrodiol glucuronidating activity by oltipraz and beta-naphthoflavone. 1997 Jan 1
22 9180355 Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat. 1997 1
23 9359487 Cure of malignant ascites and generation of protective immunity by monoclonal antibody-targeted activation of a glucuronide prodrug in rats. 1997 Nov 4 1
24 9393754 Intravenous administration of irinotecan elevates the blood beta-glucuronidase activity in rats. 1997 Dec 1 1
25 7493918 Protective effects of kampo medicines and baicalin against intestinal toxicity of a new anticancer camptothecin derivative, irinotecan hydrochloride (CPT-11), in rats. 1995 Oct 1
26 7741783 Distribution and excretion of [14C]-labelled [2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5- yl]- [2'-14C]-acetic acid in rats. 1995 Mar 1
27 8027935 Enzymatic hydrolysis of zenarestat 1-O-acylglucuronide. 1994 Mar 1
28 8106594 Determination of 18 beta-glycyrrhetinic acid in biological fluids from humans and rats by solid-phase extraction and high-performance liquid chromatography. 1993 Oct 22 1
29 8135040 Metabolism of a tetrahydroaminoacridine derivative (SM-10888) in rat: structural analysis of an N-glucuronide of SM-10888 and an O-glucuronide of hydroxylated SM-10888 by FAB-MS/MS. 1993 Dec 1
30 8216368 Studies on the reactivity of acyl glucuronides--V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and beta-glucuronidase. 1993 Oct 5 1
31 8267644 Glucuronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity. 1993 Dec 3 1
32 8327565 [Biotransformation and excretion of Z-2-amino-5-chlorobenzophenoneamidinohydrazone]. 1993 May 2
33 1643640 Specific activation of glucuronide prodrugs by antibody-targeted enzyme conjugates for cancer therapy. 1992 Aug 15 1
34 1870628 Mutagenicity of urine from rats after 1-nitropyrene and 2-nitrofluorene administration using new sensitive Salmonella typhimurium strains YG1012 and YG1024. 1991 Aug 1
35 2237261 HPLC separation and quantification of bilirubin and its glucuronide conjugates in faeces and intestinal contents of germ-free rats. 1990 Sep 2
36 2704588 The effect of saccharolactone on rat intestinal absorption of bilirubin in the presence of human breast milk. 1989 Mar 1
37 3370749 Major routes of metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in the rat. 1988 Jun 1
38 3115856 Net glucuronidation in different rat strains: importance of microsomal beta-glucuronidase. 1987 Oct 1
39 3451027 In vitro intestinal microflora-mediated metabolism of biliary metabolites from 1-nitropyrene-treated rats. 1987 1
40 3594434 Development of an experimental model for studying bladder carcinogen metabolism using the isolated rat urinary bladder. 1987 Jul 15 1
41 2870903 Impaired biliary elimination of beta-glucuronidase-resistant "glucuronides" of valproic acid after intravenous administration in the rat. Evidence for oxidative metabolism of the resistant isomers. 1986 Mar-Apr 1
42 3920383 Disposition of beta-glucuronidase-resistant "glucuronides" of valproic acid after intrabiliary administration in the rat: intact absorption, fecal excretion and intestinal hydrolysis. 1985 Apr 2
43 3978604 Stimulation of 3-benzo[a]pyrenyl glucuronide hydrolysis by calcium activation of microsomal beta-glucuronidase. 1985 Mar 1
44 6202433 Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumorigenesis by 2,5-di-O-acetyl-D-glucaro-1,4:6,3-dilactone, an in vivo beta-glucuronidase inhibitor. 1984 Jun 1
45 6488167 Characterization of mutagenic glucuronide formation from benzo(a)pyrene in the nonrecirculating perfused rat liver. 1984 Nov 1
46 6296339 Effects of dietary fiber on fecal mucinase and beta-glucuronidase activity in rats. 1983 Jan 1
47 6408946 A novel assay of glucuronidation of C- and N-hydroxylated metabolites of the carcinogen N-2-fluorenylacetamide. 1983 Apr 15 1
48 6416108 A rapid and sensitive method for the assay of UDP-glucuronosyltransferase activity toward bile acids. 1983 Sep 2
49 6126346 Urinary metabolites of 2,6-diisopropylnaphthalene in rats. 1982 Jul-Aug 1
50 6806354 Combined effect of nitrosodimethylamine and aniline on the enzyme systems of subcelluar structures. 1982 1