Colforsin

Rap guanine nucleotide exchange factor 3 ; Homo sapiens







25 Article(s)
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Title
Pub. Year
#Total Relationships
1 31864907 cAMP/EPAC Signaling Enables ETV2 to Induce Endothelial Cells with High Angiogenesis Potential. 2020 Feb 5 1
2 30717378 Combining TIR and FRET in Molecular Test Systems. 2019 Feb 2 1
3 31255721 Elevated cyclic-AMP represses expression of exchange protein activated by cAMP (EPAC1) by inhibiting YAP-TEAD activity and HDAC-mediated histone deacetylation. 2019 Oct 3
4 29377304 Regulation of human trophoblast cell syncytialization by transcription factors STAT5B and NR4A3. 2018 Jun 2
5 28512254 Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation. 2017 Jul 4 2
6 28912066 The cAMP effectors PKA and Epac activate endothelial NO synthase through PI3K/Akt pathway in human endothelial cells. 2017 Dec 1 3
7 27500354 FRET Imaging in Three-dimensional Hydrogels. 2016 Aug 1 1
8 25220136 Hydrogen peroxide stimulation of CFTR reveals an Epac-mediated, soluble AC-dependent cAMP amplification pathway common to GPCR signalling. 2015 Jan 1
9 25913012 Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells. 2015 Jul 1
10 24469067 PKA and Epac activation mediates cAMP-induced vasorelaxation by increasing endothelial NO production. 2014 Mar 3
11 24533119 Cannabinoid type 1 receptors transiently silence glutamatergic nerve terminals of cultured cerebellar granule cells. 2014 2
12 23473803 Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4). 2013 May 1 1
13 24036110 β-Adrenergic receptors activate exchange protein directly activated by cAMP (Epac), translocate Munc13-1, and enhance the Rab3A-RIM1α interaction to potentiate glutamate release at cerebrocortical nerve terminals. 2013 Oct 25 1
14 22227470 Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways. 2012 Feb 27 1
15 20032304 Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells. 2010 Feb 15 1
16 20038525 Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion. 2010 Jan 3
17 20663796 Possible role of the exchange protein directly activated by cyclic AMP (Epac) in the cyclic AMP-dependent functional differentiation and syncytialization of human placental BeWo cells. 2010 Sep 1
18 19176384 Cyclic AMP signaling as a mediator of vasculogenic mimicry in aggressive human melanoma cells in vitro. 2009 Feb 1 2
19 19385062 Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling. 2009 Jun 3
20 19472214 Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown. 2009 Sep 1
21 18495429 The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages. 2008 Aug 1
22 17565009 Cyclic AMP-dependent, protein kinase A-independent activation of extracellular signal-regulated kinase 1/2 following adenosine receptor stimulation in human umbilical vein endothelial cells: role of exchange protein activated by cAMP 1 (Epac1). 2007 Sep 2
23 16172130 Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. 2005 Nov 18 5
24 14615375 Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis. 2004 Apr 1 1
25 15525573 Progesterone secretion by luteinizing human granulosa cells: a possible cAMP-dependent but PKA-independent mechanism involved in its regulation. 2004 Oct 2