| 1 |
34979574 | Repercussion of cAMP and EPAC in Memory and Signaling. | 2022 Feb |
1 |
| 2 |
33298248 | Epac: new emerging cAMP-binding protein. | 2021 Mar |
1 |
| 3 |
33872697 | Glucagon transiently stimulates mTORC1 by activation of an EPAC/Rap1 signaling axis. | 2021 Aug |
1 |
| 4 |
34685730 | Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis. | 2021 Oct 14 |
1 |
| 5 |
32340447 | Synthesis and Biochemical Evaluation of Noncyclic Nucleotide Exchange Proteins Directly Activated by cAMP 1 (EPAC1) Regulators. | 2020 May 28 |
2 |
| 6 |
33000885 | Nitration of protein phosphatase 2A increases via Epac1/PLCĪµ/CaMKII/HDAC5/iNOS cascade in human endometrial stromal cell decidualization. | 2020 Nov |
1 |
| 7 |
31695683 | An Overview of VPAC Receptors in Rheumatoid Arthritis: Biological Role and Clinical Significance. | 2019 |
1 |
| 8 |
31817822 | A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells. | 2019 Dec 6 |
1 |
| 9 |
29111327 | Overexpression of exchange protein directly activated by cAMP-1 (EPAC1) attenuates bladder cancer cell migration. | 2018 Jan 1 |
1 |
| 10 |
27649969 | Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias. | 2017 Jul 20 |
1 |
| 11 |
27900608 | Interaction of Epac with Non-canonical Cyclic Nucleotides. | 2017 |
1 |
| 12 |
26061564 | Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion. | 2015 Jul |
2 |
| 13 |
26119090 | Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics. | 2015 Oct 10 |
2 |
| 14 |
26151319 | Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists. | 2015 Aug 13 |
1 |
| 15 |
24605759 | Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. | 2014 May 16 |
1 |
| 16 |
23143065 | Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression. | 2013 Jan |
1 |
| 17 |
23364803 | Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiology. | 2013 Apr 1 |
2 |
| 18 |
22607683 | 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. | 2012 Jun 15 |
1 |
| 19 |
23139415 | Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac. | 2012 Dec 28 |
2 |
| 20 |
21670213 | The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity. | 2011 Jun 13 |
1 |
| 21 |
19855995 | Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology. | 2010 Mar |
2 |
| 22 |
19912228 | The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function. | 2010 Jan 1 |
2 |
| 23 |
20009023 | PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans. | 2010 Mar |
1 |
| 24 |
20055708 | Epac: defining a new mechanism for cAMP action. | 2010 |
1 |
| 25 |
19307703 | Functional characterization of the cAMP-binding proteins Epac in cardiac myocytes. | 2009 Jan-Feb |
1 |
| 26 |
19546222 | Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis. | 2009 Sep 11 |
1 |
| 27 |
17716863 | Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. | 2008 Jan |
3 |
| 28 |
18176800 | Epac: effectors and biological functions. | 2008 Jun |
2 |
| 29 |
18391018 | Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes. | 2008 Jun |
1 |
| 30 |
18604457 | Epac and PKA: a tale of two intracellular cAMP receptors. | 2008 Jul |
1 |
| 31 |
18660803 | Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B. | 2008 Sep 4 |
1 |
| 32 |
17284589 | Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons. | 2007 Feb 13 |
1 |
| 33 |
17491018 | Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. | 2007 Jul 6 |
1 |
| 34 |
17565009 | Cyclic AMP-dependent, protein kinase A-independent activation of extracellular signal-regulated kinase 1/2 following adenosine receptor stimulation in human umbilical vein endothelial cells: role of exchange protein activated by cAMP 1 (Epac1). | 2007 Sep |
1 |
| 35 |
17725712 | Voltage-gated ion channel Kv4.3 is associated with Rap guanine nucleotide exchange factors and regulates angiotensin receptor type 1 signaling to small G-protein Rap. | 2007 Sep |
1 |
| 36 |
16316996 | The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane. | 2006 Feb 3 |
1 |
| 37 |
16507992 | Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation. | 2006 Mar |
3 |
| 38 |
16973695 | Cell physiology of cAMP sensor Epac. | 2006 Nov 15 |
1 |
| 39 |
15634783 | cAMP acts on exchange protein activated by cAMP/cAMP-regulated guanine nucleotide exchange protein to regulate transmitter release at the crayfish neuromuscular junction. | 2005 Jan 5 |
1 |
| 40 |
15655710 | New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells. | 2004 Nov-Dec |
1 |
| 41 |
12496249 | Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells. | 2003 Mar 7 |
1 |
| 42 |
12578910 | Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor. | 2003 Feb 17 |
1 |
| 43 |
10935551 | Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells. | 2000 Aug |
1 |
| 44 |
10486569 | Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1. | 1999 Aug 20 |
2 |