lysophosphatidic acid

epidermal growth factor receptor ; Homo sapiens







58 Article(s)
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1 33794877 CREB-dependent LPA-induced signaling initiates a pro-fibrotic feedback loop between small airway basal cells and fibroblasts. 2021 Apr 1 2
2 34658851 Lysophosphatidic Acid-Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase. 2021 2
3 32851734 Lysophosphatidic acid induces tumor necrosis factor-alpha to regulate a pro-inflammatory cytokine network in ovarian cancer. 2020 Oct 3
4 26386720 Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells. 2016 Feb 9
5 25855080 Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2. 2015 Jul 1 2
6 24928086 Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells. 2014 Jun 13 2
7 25309328 LPA-primed astrocytes induce axonal outgrowth of cortical progenitors by activating PKA signaling pathways and modulating extracellular matrix proteins. 2014 1
8 23127547 EGFR mediates LPA-induced proteolytic enzyme expression and ovarian cancer invasion: inhibition by resveratrol. 2013 Feb 2
9 23618389 The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells. 2013 Apr 24 3
10 23688423 TNF-α and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR. 2013 May 20 4
11 21782227 The NF-κB pathway mediates lysophosphatidic acid (LPA)-induced VEGF signaling and cell invasion in epithelial ovarian cancer (EOC). 2011 Oct 1
12 21832242 Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells. 2011 Nov 2
13 21914461 EGF and angiotensin II modulate lysophosphatidic acid LPA(1) receptor function and phosphorylation state. 2011 Dec 1
14 19609315 Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin. 2010 Jan 2
15 19864325 Epidermal growth factor increases lysophosphatidic acid production in human ovarian cancer cells: roles for phospholipase D2 and receptor transactivation. 2010 Jan 1
16 20074357 Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid. 2010 Jan 14 10
17 18658095 ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding. 2009 Jan 3
18 19112101 Role of acylglycerol kinase in LPA-induced IL-8 secretion and transactivation of epidermal growth factor-receptor in human bronchial epithelial cells. 2009 Mar 2
19 19201814 Modulation of epidermal growth factor receptor binding to human airway smooth muscle cells by glucocorticoids and beta2-adrenergic receptor agonists. 2009 Apr 2
20 18167312 Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells. 2008 Feb 29 1
21 18294142 Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPbeta in human bronchial epithelial cells. 2008 May 15 11
22 18309089 Lysophosphatidic acid induces rapid and sustained decreases in epidermal growth factor receptor binding via different signaling pathways in BEAS-2B airway epithelial cells. 2008 Jun 6
23 18627789 Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA(1/3), COX-2, and NF-kappaB activation- and EGFR transactivation-dependent mechanisms. 2008 Oct 2
24 18701480 Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. 2008 Aug 15 2
25 18782770 Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells. 2008 Nov 14 1
26 19116446 Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells. 2008 Dec 31 3
27 17251460 Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor. 2007 Feb 5
28 17640953 Lysophosphatidic acid decreases epidermal growth factor receptor binding in airway epithelial cells. 2007 Oct 5
29 17689924 Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin. 2007 Nov 4
30 17937769 Lysophosphatidic acid inhibits ghrelin secretion in the human gastric adenocarcinoma AGS cell line: role of mitogenic activated protein kinase signaling pathway. 2007 Nov 2
31 15920762 Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs. 2006 Jan 1
32 16289596 Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor. 2006 May 7
33 16687414 Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinases. 2006 Jul 14 7
34 15657067 Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells. 2005 Apr 2
35 15939762 A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells. 2005 Jun 6 1
36 16000575 Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer. 2005 Jul 1 4
37 16237757 Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells. 2005 Sep 28 6
38 15313912 Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. 2004 Aug 15 3
39 15337756 Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival. 2004 Nov 12 1
40 15364923 Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor. 2004 Nov 12 8
41 12627954 Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors. 2003 Mar 18 4
42 12788050 Inhibition of Ca2+/calmodulin-dependent protein kinase or epidermal growth factor receptor tyrosine kinase abolishes lysophosphatidic acid-mediated DNA-synthesis in human myometrial smooth muscle cells. 2003 2
43 12880866 Lysophosphatidic acid induces alpha1B-adrenergic receptor phosphorylation through G beta gamma, phosphoinositide 3-kinase, protein kinase C and epidermal growth factor receptor transactivation. 2003 Jul 21 1
44 14580235 Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor. 2003 Dec 15 1
45 11741820 Lysophosphatidic acid upregulates the epidermal growth factor receptor in human airway smooth muscle cells. 2002 Jan 6
46 12069816 Trans-regulation of epidermal growth factor receptor by lysophosphatidic acid and G protein-coupled receptors. 2002 May 23 2
47 12069837 Mitogenic action of LPA in prostate. 2002 May 23 2
48 12414665 Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation. 2002 Nov 1 2
49 12447997 Lysophosphatidic acid-regulated mitogenic ERK signaling in androgen-insensitive prostate cancer PC-3 cells. 2002 Dec 20 6
50 11165237 An endogenous redox molecule, thioredoxin, regulates transactivation of epidermal growth factor receptor and activation of NF-kappaB by lysophosphatidic acid. 2001 Feb 2 1