| 1 |
35242277 | Sphingosine 1-Phosphate-Upregulated COX-2/PGE2 System Contributes to Human Cardiac Fibroblast Apoptosis: Involvement of MMP-9-Dependent Transactivation of EGFR Cascade. | 2022 |
3 |
| 2 |
33609510 | Prostaglandin E2 promotes pathological retinal neovascularisation via EP4R-EGFR-Gab1-AKT signaling pathway. | 2021 Apr |
2 |
| 3 |
32546278 | 3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway. | 2020 Jun 16 |
2 |
| 4 |
32982722 | The Role of Eicosanoids in Gynecological Malignancies. | 2020 |
1 |
| 5 |
30367494 | PROSTAGLANDIN E2 stimulates cancer-related phenotypes in prostate cancer PC3 cells through cyclooxygenase-2. | 2019 May |
2 |
| 6 |
31207300 | mPGES-1 as a new target to overcome acquired resistance to gefitinib in non-small cell lung cancer cell lines. | 2019 Aug |
1 |
| 7 |
29154474 | Intracrine prostaglandin E2 pro-tumoral actions in prostate epithelial cells originate from non-canonical pathways. | 2018 Apr |
1 |
| 8 |
29180467 | YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells. | 2018 Jan 1 |
1 |
| 9 |
29447132 | Role of GPCR (mu-opioid)-receptor tyrosine kinase (epidermal growth factor) crosstalk in opioid-induced hyperalgesic priming (type II). | 2018 May |
2 |
| 10 |
29514844 | COX-2/PGE2 Axis Regulates HIF2α Activity to Promote Hepatocellular Carcinoma Hypoxic Response and Reduce the Sensitivity of Sorafenib Treatment. | 2018 Jul 1 |
1 |
| 11 |
29599917 | PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells. | 2018 Mar 13 |
11 |
| 12 |
29936588 | Eicosanoids and HB-EGF/EGFR in cancer. | 2018 Sep |
1 |
| 13 |
27377703 | Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells. | 2017 Feb |
5 |
| 14 |
27506158 | PGE2 /EP4 Signaling Controls the Transfer of the Mammary Stem Cell State by Lipid Rafts in Extracellular Vesicles. | 2017 Feb |
1 |
| 15 |
28094049 | EP4 receptor promotes invadopodia and invasion in human breast cancer. | 2017 Mar |
2 |
| 16 |
28213942 | PGE2 /EP4 receptor attenuated mucosal injury via β-arrestin1/Src/EGFR-mediated proliferation in portal hypertensive gastropathy. | 2017 May |
3 |
| 17 |
28415726 | PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells. | 2017 May 9 |
8 |
| 18 |
29272001 | Investigation on the regulatory effect of PGE2 on ESCC cells through the trans-activation of EGFR by EP2 and the relevant mechanism. | 2017 Dec |
10 |
| 19 |
27010855 | GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling. | 2016 Mar 24 |
1 |
| 20 |
27216189 | YAP Mediates Tumorigenesis in Neurofibromatosis Type 2 by Promoting Cell Survival and Proliferation through a COX-2-EGFR Signaling Axis. | 2016 Jun 15 |
1 |
| 21 |
25749386 | Radiation-induced PGE2 sustains human glioma cells growth and survival through EGF signaling. | 2015 Mar 30 |
2 |
| 22 |
25828575 | Intracellular EP2 prostanoid receptor promotes cancer-related phenotypes in PC3 cells. | 2015 Sep |
1 |
| 23 |
26033830 | Randomized phase 2 trial of erlotinib in combination with high-dose celecoxib or placebo in patients with advanced non-small cell lung cancer. | 2015 Sep 15 |
2 |
| 24 |
26058972 | Prostaglandin E2 promotes human cholangiocarcinoma cell proliferation, migration and invasion through the upregulation of β-catenin expression via EP3-4 receptor. | 2015 Aug |
1 |
| 25 |
26113609 | mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity. | 2015 Aug |
3 |
| 26 |
24378923 | Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression. | 2014 Mar |
3 |
| 27 |
24626807 | Prostaglandin E₂ receptor EP2 mediates Snail expression in hepatocellular carcinoma cells. | 2014 May |
1 |
| 28 |
24760275 | Prostaglandin E2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells. | 2014 Jul |
1 |
| 29 |
24953041 | Prostaglandin E2 induces retinoic acid receptor-β up-regulation through MSK1. | 2014 Sep |
6 |
| 30 |
25103627 | CCR5 expression is elevated in cervical cancer cells and is up-regulated by seminal plasma. | 2014 Nov |
2 |
| 31 |
25240937 | Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor. | 2014 Sep 21 |
3 |
| 32 |
23394575 | Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE2 dependent pathway. | 2013 Feb 9 |
1 |
| 33 |
23525457 | Prostaglandin E₂ receptor EP1-mediated phosphorylation of focal adhesion kinase enhances cell adhesion and migration in hepatocellular carcinoma cells. | 2013 May |
2 |
| 34 |
23644172 | Epidermal growth factor receptor transactivation by intracellular prostaglandin E2-activated prostaglandin E2 receptors. Role in retinoic acid receptor-β up-regulation. | 2013 Sep |
10 |
| 35 |
23973650 | Induction of cyclooxygenase-2 expression by prostaglandin E2 stimulation of the prostanoid EP4 receptor via coupling to Gαi and transactivation of the epidermal growth factor receptor in HCA-7 human colon cancer cells. | 2013 Oct 15 |
1 |
| 36 |
24092824 | EGF-like growth factors induce COX-2-derived PGE2 production through ERK1/2 in human granulosa cells. | 2013 Dec |
3 |
| 37 |
22791816 | Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts. | 2012 Oct |
2 |
| 38 |
22815767 | Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis. | 2012 |
1 |
| 39 |
20705717 | Chorionic gonadotrophin regulates CXCR4 expression in human endometrium via E-series prostanoid receptor 2 signalling to PI3K-ERK1/2: implications for fetal-maternal crosstalk for embryo implantation. | 2011 Jan |
1 |
| 40 |
20850495 | Involvement of the epidermal growth factor receptor in Pb²+-induced activation of cPLA₂/COX-2 genes and PGE₂ production in vascular smooth muscle cells. | 2011 Jan 11 |
1 |
| 41 |
21294165 | Signaling pathways of ATP-induced PGE2 release in spinal cord astrocytes are EGFR transactivation-dependent. | 2011 Apr |
1 |
| 42 |
21925169 | Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells. | 2011 Nov 1 |
2 |
| 43 |
19127349 | Leptin-induced cytosolic phospholipase A2 activation in gastric mucosal protection against ethanol cytotoxicity involves epidermal growth factor receptor transactivation. | 2009 Feb |
1 |
| 44 |
19201881 | Lipopolysaccharide initiates a positive feedback of epidermal growth factor receptor signaling by prostaglandin E2 in human biliary carcinoma cells. | 2009 Feb 15 |
1 |
| 45 |
19717552 | Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells. | 2009 Nov |
1 |
| 46 |
18294142 | Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPbeta in human bronchial epithelial cells. | 2008 May 15 |
2 |
| 47 |
16905765 | Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway. | 2007 Jan |
1 |
| 48 |
17384145 | EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways. | 2007 Aug |
2 |
| 49 |
17477350 | Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling. | 2007 Dec |
1 |
| 50 |
17550984 | Signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non small-cell lung cancer. | 2007 Sep |
2 |