Tyrphostins

epidermal growth factor receptor ; Homo sapiens







92 Article(s)
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51 14563126 Tumor specific activation of PKR as a non-toxic modality of cancer treatment. 2003 Aug 2
52 14674888 Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes. 2003 Dec 1
53 12209987 Antagonistic and agonistic effects of quinazoline tyrosine kinase inhibitors on mutant EGF receptor function. 2002 Sep 10 1
54 12244120 Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling. 2002 Nov 29 1
55 12402303 Submicromolar doses of alkyl-lysophospholipids induce rapid internalization, but not activation, of epidermal growth factor receptor and concomitant MAPK/ERK activation in A431 cells. 2002 Dec 1 1
56 12414665 Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation. 2002 Nov 1 1
57 12435806 Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor. 2002 Dec 2
58 11309250 Phenolic antioxidants trolox and caffeic acid modulate the oxidized LDL-induced EGF-receptor activation. 2001 Apr 1
59 11313882 The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells. 2001 Mar 15 1
60 11352836 Arginine vasopressin stimulates mesangial cell proliferation by activating the epidermal growth factor receptor. 2001 Jun 2
61 11763154 Biological activity of tyrosine kinase inhibitors: novel agents for psoriasis therapy. 2001 Nov 1
62 10722725 Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells. 2000 Mar 24 1
63 10734059 Tumor necrosis factor-alpha and interleukin-1beta inhibit apolipoprotein B secretion in CaCo-2 cells via the epidermal growth factor receptor signaling pathway. 2000 Mar 31 1
64 10777553 Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src). 2000 Apr 28 1
65 10816385 Retinoic acid affects the EGF-R signaling pathway during differentiation induction of human endometrial adenocarcinoma cells. 2000 Jun 2
66 10877829 Involvement of the epidermal growth factor receptor in epithelial repair in asthma. 2000 Jul 1
67 10916078 Angiotensin II-induced growth of vascular smooth muscle cells requires an Src-dependent activation of the epidermal growth factor receptor. 2000 Aug 2
68 11016663 Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells. 2000 Sep 15 2
69 10084649 Tyrosine kinase inhibitors as antiproliferative agents against an estrogen-dependent breast cancer cell line in vitro. 1999 Feb 4
70 10508495 ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells. 1999 Nov 12 1
71 9648731 Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor. 1998 Jun 29 1
72 9765228 Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion. 1998 Oct 16 2
73 9811719 Adeno-associated virus type 2-mediated gene transfer: role of epidermal growth factor receptor protein tyrosine kinase in transgene expression. 1998 Dec 4
74 9822606 Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. 1998 Nov 16 1
75 9833772 Inhibition of human bladder cancer cell motility by genistein is dependent on epidermal growth factor receptor but not p21ras gene expression. 1998 Dec 9 1
76 9044042 EGF-R dependent regulation of keratinocyte survival. 1997 Jan 1
77 9065732 Epidermal growth factor receptor signaling cascade as target for tyrphostin (RG 50864) in epithelial cells. Paradoxical effects on mitogen-activated protein kinase kinase and mitogen-activated protein kinase activities. 1997 Feb 7 10
78 9177208 An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors. 1997 Jun 10 2
79 9233779 Induction of tyrosine phosphorylation and association of beta-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence. 1997 Jul 3 2
80 9237626 Tyrphostin AG 494 blocks Cdk2 activation. 1997 Jun 30 1
81 8752145 Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors. 1996 Sep 1 1
82 8960549 Tyrphostins. 6. Dimeric benzylidenemalononitrile tyrophostins: potent inhibitors of EGF receptor tyrosine kinase in vitro. 1996 Dec 6 4
83 21544401 Growth inhibition of gastric cancer cell lines by the tyrphostin RG13022 and its effects on intracellular signalling. 1996 Mar 1
84 8538164 Antiproliferative effects of tyrosine kinase inhibitors (tyrphostins) on human bladder and renal carcinoma cells. 1995 Dec 2
85 7525598 Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. 1994 Nov 2
86 7916898 Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties. 1994 Aug 1
87 8057149 Effect of tyrphostin on cell growth and tyrosine kinase activity of epidermal growth factor receptor in human gliomas. 1994 Sep 1
88 8083760 Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain. 1994 Sep 1
89 8183246 Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program. 1994 Apr 3
90 8297123 Antiproliferative effect of tyrosine kinase inhibitors in epidermal growth factor-stimulated growth of human gastric cancer cells. 1993 Nov-Dec 1
91 1676428 Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. 1991 Jun 1
92 2555218 Tyrphostins inhibit the epidermal growth factor receptor-mediated breakdown of phosphoinositides. 1989 Nov 6 1