Niacinamide

sirtuin 1 ; Homo sapiens







149 Article(s)
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51 29118980 SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development. 2017 1
52 26055227 Paliperidone Protects SH-SY5Y Cells Against MK-801-Induced Neuronal Damage Through Inhibition of Ca(2+) Influx and Regulation of SIRT1/miR-134 Signal Pathway. 2016 May 1
53 26483208 Protective effect of trans-δ-viniferin against high glucose-induced oxidative stress in human umbilical vein endothelial cells through the SIRT1 pathway. 2016 1
54 26660162 The SIRT1 inhibitor, nicotinamide, inhibits hepatitis B virus replication in vitro and in vivo. 2016 Mar 2
55 26723256 SIRT1 regulates accumulation of oxidized LDL in HUVEC via the autophagy-lysosomal pathway. 2016 Jan 2
56 27023330 Role of the Substrate Specificity-Defining Residues of Human SIRT5 in Modulating the Structural Stability and Inhibitory Features of the Enzyme. 2016 1
57 27050994 Effects of Sirtuin 1 on the proliferation and osteoblastic differentiation of periodontal ligament stem cells and stem cells from apical papilla. 2016 Mar 24 1
58 27414406 Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project. 2016 1
59 27608947 NAMPT inhibition synergizes with NQO1-targeting agents in inducing apoptotic cell death in non-small cell lung cancer cells. 2016 Aug 2
60 27708228 SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells. 2016 Nov 15 1
61 25472572 Icariin protects against intestinal ischemia-reperfusion injury. 2015 Mar 1
62 25751058 Acetylation site specificities of lysine deacetylase inhibitors in human cells. 2015 Apr 1
63 25815111 SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer. 2015 Mar 26 1
64 26194321 Donepezil attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells through SIRT1 activation. 2015 Sep 2
65 26330291 A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling. 2015 Dec 1
66 26352206 Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation. 2015 Nov 1
67 27512785 Epigenetics in ADPKD: Understanding Mechanisms and Discovering Treatment 2015 Nov 2
68 24022598 The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells. 2014 Feb 1
69 24446069 Exendin-4 attenuates endoplasmic reticulum stress through a SIRT1-dependent mechanism. 2014 Sep 1
70 24557422 Sirtuin 1-mediated inhibition of p66shc expression alleviates liver ischemia/reperfusion injury. 2014 May 1
71 24729176 Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells. 2014 Aug 2
72 24845634 Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1. 2014 May 20 1
73 24880902 Structure-activity relationship and interaction studies of new SIRT1 inhibitors with the scaffold of 3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole. 2014 Jul 15 1
74 25004063 Novel role of resveratrol: suppression of high-mobility group protein box 1 nucleocytoplasmic translocation by the upregulation of sirtuin 1 in sepsis-induced liver injury. 2014 Nov 2
75 25004411 Studying SIRT6 regulation using H3K56 based substrate and small molecules. 2014 Oct 15 1
76 25057854 Quercetin, luteolin, and epigallocatechin gallate promote glucose disposal in adipocytes with regulation of AMP-activated kinase and/or sirtuin 1 activity. 2014 Aug 3
77 25349818 Molecular Links between Caloric Restriction and Sir2/SIRT1 Activation. 2014 Oct 1
78 22537175 Expression patterns and potential roles of SIRT1 in human medulloblastoma cells in vivo and in vitro. 2013 Feb 1
79 23022493 Resveratrol preconditioning increases methionine sulfoxide reductases A expression and enhances resistance of human neuroblastoma cells to neurotoxins. 2013 Jun 3
80 23092114 Novel directions for diabetes mellitus drug discovery. 2013 Jan 1
81 23135526 Expression of SIRT1 in choroidal neovascular membranes. 2013 Apr 1
82 23313797 Neuroprotective effects of resveratrol on embryonic dorsal root ganglion neurons with neurotoxicity induced by ethanol. 2013 May 1
83 23363613 SIRT1 regulates the human alveolar epithelial A549 cell apoptosis induced by Pseudomonas aeruginosa lipopolysaccharide. 2013 1
84 23479127 SIRT1 inhibits TNF-α-induced apoptosis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1. 2013 Jun 1
85 23561972 Nicotinamide prohibits proliferation and enhances chemosensitivity of pancreatic cancer cells through deregulating SIRT1 and Ras/Akt pathways. 2013 Mar-Apr 2
86 23588928 Hydrogen sulfide prevents H₂O₂-induced senescence in human umbilical vein endothelial cells through SIRT1 activation. 2013 Jun 2
87 23603572 PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway. 2013 Jun 10 1
88 23652462 SIRT1 prevents atherosclerosis via liver‑X‑receptor and NF‑κB signaling in a U937 cell model. 2013 Jul 1
89 23922917 SIRT1 is a direct coactivator of thyroid hormone receptor β1 with gene-specific actions. 2013 2
90 23977047 Nurr1 represses tyrosine hydroxylase expression via SIRT1 in human neural stem cells. 2013 1
91 24040102 Regulation of FOXOs and p53 by SIRT1 modulators under oxidative stress. 2013 1
92 24127549 Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer. 2013 Oct 1
93 24137378 Nicotinamide-mediated inhibition of SIRT1 deacetylase is associated with the viability of cancer cells exposed to antitumor agents and apoptosis. 2013 Aug 1
94 22198152 Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment. 2012 Apr 1
95 22204321 NAD+ metabolism and NAD(+)-dependent enzymes: promising therapeutic targets for neurological diseases. 2012 Feb 1
96 22302044 SirT1 confers hypoxia-induced radioresistance via the modulation of c-Myc stabilization on hepatoma cells. 2012 3
97 22385246 Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells. 2012 Apr 4
98 22465780 Nicotinamide treatment reduces the levels of histone H3K4 trimethylation in the promoter of the mper1 circadian clock gene and blocks the ability of dexamethasone to induce the acute response. 2012 Aug 1
99 22493485 Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation. 2012 Jun 1 2
100 22539994 Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation. 2012 5