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35251333 | Sirtuin 1 participates in intervertebral disc degeneration via the nicotinamide phosphoribosyl transferase/nicotinamide adenine dinucleotide/sirtuin 1 pathway responsible for regulating autophagy of nucleus pulposus cells. | 2022 Apr |
2 |
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35301252 | Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity. | 2022 Mar |
1 |
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35566069 | A Novel Mechanism for SIRT1 Activators That Does Not Rely on the Chemical Moiety Immediately C-Terminal to the Acetyl-Lysine of the Substrate. | 2022 Apr 22 |
1 |
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35633910 | Sirtuin1 attenuates acute liver failure by reducing reactive oxygen species via hypoxia inducible factor 1α. | 2022 May 7 |
1 |
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32894639 | Modulation of antioxidant enzymes, SIRT1 and NF-κB by resveratrol and nicotinamide in alcohol-aflatoxin B1-induced hepatocellular carcinoma. | 2021 Jan |
1 |
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33610183 | Silymarin modulates catabolic cytokine expression through Sirt1 and SOX9 in human articular chondrocytes. | 2021 Feb 20 |
1 |
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33670751 | Substrate-Dependent Sensitivity of SIRT1 to Nicotinamide Inhibition. | 2021 Feb 18 |
1 |
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33710861 | Olmesartan Prevents Oligomerized Amyloid β (Aβ)-Induced Cellular Senescence in Neuronal Cells. | 2021 Apr 7 |
1 |
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33738067 | Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors. | 2021 Mar 11 |
1 |
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33802063 | Nicotinamide Treatment Facilitates Mitochondrial Fission through Drp1 Activation Mediated by SIRT1-Induced Changes in Cellular Levels of cAMP and Ca2. | 2021 Mar 10 |
3 |
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34184746 | USP31 acetylation at Lys1264 is essential for its activity and cervical cancer cell growth. | 2021 Jul 28 |
2 |
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31407410 | Nicotinamide increases the sensitivity of chronic myeloid leukemia cells to doxorubicin via the inhibition of SIRT1. | 2020 Jan |
4 |
| 13 |
31753397 | Synovium stem cell-derived matrix enhances anti-inflammatory properties of rabbit articular chondrocytes via the SIRT1 pathway. | 2020 Jan |
2 |
| 14 |
31769563 | Nicotinamide-induced silencing of SIRT1 by miR-22-3p increases periodontal ligament stem cell proliferation and differentiation. | 2020 Mar |
1 |
| 15 |
32296111 | s-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand-foot skin reaction that can be reversed by nicotinamide. | 2020 Sep |
1 |
| 16 |
32340156 | Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation. | 2020 Apr 23 |
2 |
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32469848 | Nicotinamide Inhibits Glycolysis of HL-60 Cells by Modulating Sirtuin 1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Coactivator 1α (PGC-1α)/Hypoxia-Inducible Factor-2α (HIF2α) Signaling Pathway. | 2020 May 29 |
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32531731 | Evidence for NAD+-dependent histone dynamics and tunneling associated conformational transitions in circadian deacetylase SIRT1. | 2020 Sep |
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| 19 |
32572902 | Sirt1 suppresses MCP-1 production during the intervertebral disc degeneration by inactivating AP-1 subunits c-Fos/c-Jun. | 2020 Jun |
3 |
| 20 |
32733649 | Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway. | 2020 Jul 14 |
2 |
| 21 |
33319867 | NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro. | 2020 Dec 15 |
1 |
| 22 |
33613450 | 17β-Estradiol Induces Mitophagy Upregulation to Protect Chondrocytes via the SIRT1-Mediated AMPK/mTOR Signaling Pathway. | 2020 |
2 |
| 23 |
30548678 | Suppression of microRNA-141 suppressed p53 to protect against neural apoptosis in epilepsy by SIRT1 expression. | 2019 Jun |
3 |
| 24 |
30648523 | Nicotinamide Overcomes Doxorubicin Resistance of Breast Cancer Cells through Deregulating SIRT1/Akt Pathway. | 2019 |
5 |
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30789361 | Evodiamine inhibits migration and invasion by Sirt1-mediated post-translational modulations in colorectal cancer. | 2019 Jul |
1 |
| 26 |
31146723 | Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway. | 2019 May 30 |
1 |
| 27 |
31491460 | Induction of autophagy under nitrosative stress: A complex regulatory interplay between SIRT1 and AMPK in MCF7 cells. | 2019 Dec |
1 |
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31553614 | Unraveling the Unbinding Pathways of Products Formed in Catalytic Reactions Involved in SIRT1-3: A Random Acceleration Molecular Dynamics Simulation Study. | 2019 Oct 28 |
1 |
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31614144 | High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor. | 2019 Dec 15 |
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31638409 | Resveratrol inhibits high-glucose-induced inflammatory "metabolic memory" in human retinal vascular endothelial cells through SIRT1-dependent signaling. | 2019 Dec |
2 |
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31993545 | SIRT1 Knockdown Enhances the Differentiation of Human Embryonic Stem Cells into Pancreatic β Cells. | 2019 Dec |
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28107614 | SIRT1-dependent anti-senescence effects of cell-deposited matrix on human umbilical cord mesenchymal stem cells. | 2018 Feb |
3 |
| 33 |
28750181 | SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61 expression. | 2018 May |
3 |
| 34 |
29251317 | Ethanol extract of Patrinia scabiosaefolia induces the death of human renal cell carcinoma 786-O cells via SIRT-1 and mTOR signaling-mediated metabolic disruptions. | 2018 Feb |
1 |
| 35 |
29380418 | Spontaneous up-regulation of SIRT1 during osteogenesis contributes to stem cells' resistance to oxidative stress. | 2018 Jun |
2 |
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29805651 | Nicotinamide N-methyltransferase enhances the progression of prostate cancer by stabilizing sirtuin 1. | 2018 Jun |
1 |
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29844677 | The Influence of Nicotinamide on Health and Disease in the Central Nervous System. | 2018 |
2 |
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30105071 | Involvement of Flavonoids from the Leaves of Carya cathayensis Sarg. in Sirtuin 1 Expression in HUVEC Senescence. | 2018 |
1 |
| 39 |
30116472 | Upregulation of SIRT1 by Kartogenin Enhances Antioxidant Functions and Promotes Osteogenesis in Human Mesenchymal Stem Cells. | 2018 |
1 |
| 40 |
30203236 | Novel 1,4-dihydropyridine induces apoptosis in human cancer cells through overexpression of Sirtuin1. | 2018 Oct |
1 |
| 41 |
30464525 | Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK. | 2018 |
1 |
| 42 |
28000862 | SIRT1‑mediated regulation of oxidative stress induced by Pseudomonas aeruginosa lipopolysaccharides in human alveolar epithelial cells. | 2017 Feb |
1 |
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28139552 | Inhibition of Hydrogen Peroxide-Induced Human Umbilical Vein Endothelial Cells Aging by Allicin Depends on Sirtuin1 Activation. | 2017 Jan 31 |
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28351214 | Extremely low-frequency electromagnetic field promotes astrocytic differentiation of human bone marrow mesenchymal stem cells by modulating SIRT1 expression. | 2017 Jul |
1 |
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28417163 | Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells. | 2017 Sep |
1 |
| 46 |
28473059 | Nicotinamide protects hepatocytes against palmitate-induced lipotoxicity via SIRT1-dependent autophagy induction. | 2017 Apr |
3 |
| 47 |
28608449 | Resveratrol suppresses lipoprotein-associated phospholipase A2 expression by reducing oxidative stress in macrophages and animal models. | 2017 Oct |
2 |
| 48 |
28627707 | Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1. | 2017 Aug |
2 |
| 49 |
28693188 | Consecutive stimulation of HBsAg promotes the viability of the human B lymphoblastoid cell line IM-9 through regulating the SIRT1-NF-κB pathway. | 2017 Jul |
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28736426 | Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and Mitophagy. | 2017 Jul 31 |
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