Tegafur

thymidylate synthetase ; Homo sapiens







23 Article(s)
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1 32838518 Multiaction Platinum(IV) Prodrug Containing Thymidylate Synthase Inhibitor and Metabolic Modifier against Triple-Negative Breast Cancer. 2020 Sep 8 1
2 30944635 5-Fluorouracil-based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase. 2019 May 2
3 28835573 Higher Tissue Levels of Thymidylate Synthase Determined by ELISA Are Associated with Poor Prognosis of Patients with Lung Cancer. 2017 Aug 1
4 25922722 Variability in the anti-tumor effect of tegafur-uracil depending on histologic types of lung cancer. 2015 Mar 4
5 20647221 Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study. 2011 Feb 2
6 22870097 Effect of leucovorin on the antitumor efficacy of the 5-FU prodrug, tegafur-uracil, in human colorectal cancer xenografts with various expression levels of thymidylate synthase. 2010 Nov 1
7 17143493 Cyclophosphamide augments the anti-tumor efficacy of uracil and tegafur by inhibiting dihydropyrimidine dehydrogenase. 2007 Jan 3
8 17695427 Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (tegafur+uracil) in patients with non-small cell lung cancer. 2007 Jul-Aug 1
9 15785747 Clinical application of biological markers for treatments of resectable non-small-cell lung cancers. 2005 Apr 11 1
10 15218314 Low thymidylate synthase expression in the primary tumor predicts favorable clinical outcome in resected gastric cancer patients treated with adjuvant tegafur. 2004 3
11 14636615 Predictive value of immunohistochemical thymidylate synthase expression for histological response to Tegafur/Uracil (UFT) in oral squamous cell carcinoma. 2003 Dec 4
12 11201382 [Theoretical construction of chemotherapeutic tactics for advanced or recurrent gastrointestinal carcinoma]. 2001 Jan 1
13 12450432 Thymidylate synthase pharmacogenetics in colorectal cancer. 2001 Nov 4
14 10769701 Do the expression of CD44, apoptosis and thymidylate synthase inhibition rate correlate with the efficacy of chemotherapy in colorectal cancer? 2000 Jan-Feb 1
15 9239165 [Study of preoperative combination therapy with UFT + CDDP in patients with gastric and colorectal cancer--concomitant effects based on the thymidylate synthase inhibitory rat]. 1997 Jul 1
16 8765432 Thymidylate synthase inhibition by an oral regimen consisting of tegafur-uracil (UFT) and low-dose leucovorin for patients with gastric cancer. 1996 2
17 7487125 [UFT/CDDP preoperative chemotherapy for progressive gastric cancer--histological antitumor effects and thymidylate synthase inhibition rate]. 1995 Nov 1
18 8464418 [Changes of the number of FdUMP binding sites of thymidylate synthase and folate pools in human colorectal carcinomas following the administration of tegafur and uracil: preliminary report]. 1993 Feb 1
19 8468974 Dependence of the thymidylate synthase inhibition rate on the interval after the last administration of tegafur in sigmoid colon cancer patients. 1993 Feb 1
20 1519926 [Neo-adjuvant chemotherapy with tegafur suppository for rectal cancer--evaluation of the antitumor effects, tissue levels of 5-FU and inhibition of thymidylate synthase. Tochigi Colorectal Cancer Study Group]. 1992 Sep 1
21 1992915 [Drug concentration in cancerous large bowel tissue and thymidylate synthase inhibition rate after administration of tegafur and UFT]. 1991 Feb 1
22 2495166 5-Fluorouracil and UFT-sensitive gastric carcinoma has a high level of thymidylate synthase. 1989 May 1 6
23 6426401 [Studies on the mechanism of antitumor activity of 5-FU and its derivatives--relationship between the inhibition of tumor growth and the inhibition of thymidylate synthetase in vivo]. 1984 May 1