1,2,3,4-tetrahydroisoquinoline

phenylethanolamine N-methyltransferase ; Homo sapiens







11 Article(s)
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1 18024134 Synthesis of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines and comparison with their isosteric 1,2,3,4-tetrahydroisoquinolines as inhibitors of phenylethanolamine N-methyltransferase. 2008 Jan 1 2
2 17126018 Exploring the active site of phenylethanolamine N-methyltransferase with 1,2,3,4-tetrahydrobenz[h]isoquinoline inhibitors. 2007 Feb 1 3
3 11504632 Effects of a 3-alkyl-, 4-hydroxy- and/or 8-aromatic-substituent on the phenylethanolamine N-methyltransferase inhibitor potency and alpha2-adrenoceptor affinity of 2,3,4,5-tetrahydro-1H-2-benzazepines. 2001 Aug 1
4 10354406 3,7-Disubstituted-1,2,3,4-tetrahydroisoquinolines display remarkable potency and selectivity as inhibitors of phenylethanolamine N-methyltransferase versus the alpha2-adrenoceptor. 1999 Jun 3 1
5 10400340 1,3-Dimethyl-7-substituted-1,2,3,4-tetrahydroisoquinolines as probes for the binding orientation of tetrahydroisoquinoline at the active site of phenylethanolamine N-methyltransferase. 1999 May 2
6 10464018 Synthesis and evaluation of 3-trifluoromethyl-7-substituted-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor. 1999 Aug 26 1
7 8784452 Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-methyltransferase. 1996 Aug 30 4
8 3339613 Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines. 1988 Feb 1
9 3351861 Synthesis and evaluation of 3-substituted analogues of 1,2,3,4-tetrahydroisoquinoline as inhibitors of phenylethanolamine N-methyltransferase. 1988 Apr 8
10 3681890 Inhibition of phenylethanolamine N-methyltransferase (PNMT) by aromatic hydroxy-substituted 1,2,3,4,-tetrahydroisoquinolines: further studies on the hydrophilic pocket of the aromatic ring binding region of the active site. 1987 Dec 2
11 6674125 Quantitative structure-activity relationship studies of 1,2,3,4-tetrahydroisoquinoline derivatives as inhibitors of phenylethanolamine N-methyltransferase. 1983 Dec 1