Uric Acid

interleukin 1 beta ; Mus musculus







32 Article(s)
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1 34376811 Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways. 2022 May 2
2 31511642 Suppression of monosodium urate crystal-induced inflammation by inhibiting TGF-β-activated kinase 1-dependent signaling: role of the ubiquitin proteasome system. 2021 Jan 1
3 34577821 Ameliorative Effects of Cardamonin on Monosodium Urate-Induced Gouty Arthritis through Inhibiting NLRP3 Inflammasome Mediation. 2021 Aug 28 1
4 31298290 Monosodium urate crystal interleukin-1β release is dependent on Toll-like receptor 4 and transient receptor potential V1 activation. 2020 Jan 1 1
5 31883118 Eucalyptol alleviates inflammation and pain responses in a mouse model of gout arthritis. 2020 May 1
6 31918161 IκBζ controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene. 2020 Mar 1
7 30806957 MSU Crystals Enhance TDB-Mediated Inflammatory Macrophage IL-1β Secretion. 2019 Jun 2
8 31616405 Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal. 2019 1
9 31803174 Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation. 2019 1
10 28376889 Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression. 2017 Apr 4 3
11 28986252 Uric acid demonstrates neuroprotective effect on Parkinson's disease mice through Nrf2-ARE signaling pathway. 2017 Dec 2 1
12 26868525 Macrophage migration inhibitory factor drives neutrophil accumulation by facilitating IL-1β production in a murine model of acute gout. 2016 Jun 1
13 27234527 Epigallocatechin gallate inhibits urate crystals-induced peritoneal inflammation in C57BL/6 mice. 2016 Oct 2
14 27271513 Enhanced p62 Is Responsible for Mitochondrial Pathway-Dependent Apoptosis and Interleukin-1β Production at the Early Phase by Monosodium Urate Crystals in Murine Macrophage. 2016 Oct 2
15 27412397 Erratum to: Enhanced p62 is Responsible for Mitochondrial Pathway-Dependent Apoptosis and Interleukin-1β Production at the Early Phase by Monosodium Urate Crystals in Murine Macrophage. 2016 Oct 1
16 27542954 Enhanced alpha-kinase 1 accelerates multiple early nephropathies in streptozotocin-induced hyperglycemic mice. 2016 Nov 1
17 25681332 The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. 2015 Mar 15 1
18 25914377 A Role for Gut Microbiota and the Metabolite-Sensing Receptor GPR43 in a Murine Model of Gout. 2015 Jun 4
19 26100496 Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice. 2015 Nov 2
20 24943488 Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice. 2014 Oct 1
21 22933241 Orthopedic wear debris mediated inflammatory osteolysis is mediated in part by NALP3 inflammasome activation. 2013 Jan 2
22 23576175 Attenuation of gouty arthritis by emodinol in monosodium urate crystal-treated mice. 2013 May 1
23 23980097 The Nlrp3 inflammasome regulates acute graft-versus-host disease. 2013 Sep 23 1
24 22147847 Inflammasome-IL-1-Th17 response in allergic lung inflammation. 2012 Feb 2
25 22904305 Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse models. 2012 Sep 15 1
26 22002608 Non-canonical inflammasome activation targets caspase-11. 2011 Oct 16 1
27 20662061 Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. 2010 Nov 1
28 19218193 Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. 2009 May 15 4
29 19528034 Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. 2009 Oct 3
30 20007584 IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. 2009 Dec 15 1
31 15784009 Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner. 2005 Jul 15 2
32 16142712 Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. 2005 Sep 1