Topotecan

ATM serine/threonine kinase ; Homo sapiens







9 Article(s)
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Pub. Year
#Total Relationships
1 30622252 ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks. 2019 Jan 8 2
2 28477120 ATM Activation and H2AX Phosphorylation Induced by Genotoxic Agents Assessed by Flow- and Laser Scanning Cytometry. 2017 1
3 25701194 ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells. 2015 2
4 23928469 ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks. 2013 Sep 3
5 20662736 Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2. 2010 Aug 1
6 18802408 Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation. 2008 Oct 2
7 16426422 ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis. 2006 Feb 3
8 16760673 Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine. 2006 Aug 1
9 16184611 Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis. 2005 Nov 1