fludarabine

ATM serine/threonine kinase ; Homo sapiens







12 Article(s)
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1 34886743 Fludarabine nucleoside induces major changes in the p53 interactome in human B-lymphoid cancer cell lines. 2022 1
2 27678008 Major prognostic value of complex karyotype in addition to TP53 and IGHV mutational status in first-line chronic lymphocytic leukemia. 2017 Dec 1
3 24057147 Valproic acid enhances fludarabine-induced apoptosis mediated by ROS and involving decreased AKT and ATM activation in B-cell-lymphoid neoplastic cells. 2014 Jan 3
4 24144307 The histone deacetylase inhibitor SAHA sensitizes acute myeloid leukemia cells to a combination of nucleoside analogs and the DNA-alkylating agent busulfan. 2014 Jul 2
5 23585524 ATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin. 2013 Jul 1
6 22149137 The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease. 2012 Jul 1
7 22369572 Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study. 2012 Sep 1
8 23091097 Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial. 2012 Dec 20 1
9 20933509 The synergistic cytotoxicity of clofarabine, fludarabine and busulfan in AML cells involves ATM pathway activation and chromatin remodeling. 2011 Jan 15 2
10 21270755 DNA-PK, ATM and MDR proteins inhibitors in overcoming fludarabine resistance in CLL cells. 2010 Dec 2
11 19018867 Presence of heterozygous ATM deletion may not be critical in the primary response of chronic lymphocytic leukemia cells to fludarabine. 2009 Feb 1
12 16543464 Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia. 2006 Aug 1 2